Skeletal Aging and Osteoporosis

Skeletal Aging and Osteoporosis PDF Author: Matthew J. Silva
Publisher: Springer Science & Business Media
ISBN: 3642180531
Category : Technology & Engineering
Languages : en
Pages : 261

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Book Description
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

Skeletal Aging and Osteoporosis

Skeletal Aging and Osteoporosis PDF Author: Matthew J. Silva
Publisher: Springer Science & Business Media
ISBN: 3642180531
Category : Technology & Engineering
Languages : en
Pages : 261

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Book Description
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

The Aging Skeleton

The Aging Skeleton PDF Author: Clifford J. Rosen
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 674

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Book Description
The Aging Skeleton provides students and clinicians with a comprehensive review of all aspects of the human skeleton as it ages. It offers information on basic mechanisms and pathways as well as pathobiology.

Human Cell Transformation

Human Cell Transformation PDF Author: Johng S. Rhim
Publisher: Springer Nature
ISBN: 3030222543
Category : Science
Languages : en
Pages : 246

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Book Description
This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.

Bone Health and Osteoporosis

Bone Health and Osteoporosis PDF Author: United States Public Health Service
Publisher:
ISBN: 9781410219275
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.

Biochemistry and Cell Biology of Ageing: Part II Clinical Science

Biochemistry and Cell Biology of Ageing: Part II Clinical Science PDF Author: J. Robin Harris
Publisher: Springer
ISBN: 9811336814
Category : Medical
Languages : en
Pages : 502

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Book Description
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.

Osteoporosis

Osteoporosis PDF Author: Byron Lawrence Riggs
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 552

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Book Description


Osteosarcopenia: Bone, Muscle and Fat Interactions

Osteosarcopenia: Bone, Muscle and Fat Interactions PDF Author: Gustavo Duque
Publisher: Springer Nature
ISBN: 3030258904
Category : Science
Languages : en
Pages : 382

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Book Description
This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Osteoporosis in Men

Osteoporosis in Men PDF Author: Eric S. Orwoll
Publisher: Academic Press
ISBN: 0080923461
Category : Medical
Languages : en
Pages : 764

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Book Description
Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. - Brings together more eminent investigators and clinicians to interpret developments in this growing field - Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy - There is no book on the market that covers osteoporosis in men as comprehensively as this book

Bone Loss and Osteoporosis

Bone Loss and Osteoporosis PDF Author: Sabrina C. Agarwal
Publisher: Springer Science & Business Media
ISBN: 1441988912
Category : Social Science
Languages : en
Pages : 431

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Book Description
With the growing incidence of fragility fractures in Europe and North America over the last three decades, bone loss and osteoporosis have become active areas of research in skeletal biology. Bone loss is associated with aging in both sexes and is accelerated in women with the onset of menopause. However, bone loss is related to a suite of complex and often synergistically related factors including genetics, pathology, nutrition, mechani cal usage, and lifestyle. It is not surprising that its incidence and severity vary among populations. There has been increasing interest to investigate bone loss and osteoporosis from an anthropological perspective that utilizes a biocultural approach. Biocultural approaches recognize the inter-relationship between biological, cultural, and environmental variables. Anthropological studies also highlight the value of evolutionary and population approaches to the study of bone loss. These approaches are particularly suited to elucidate the multifactorial etiology of bone loss. The idea for this volume came out of a symposium organized by the editors at the 70th annual meeting of The American Association of Physical Anthropologists in Kansas City, Missouri. Many of the symposium participants, along with several additional leading scientists involved in bone and osteoporosis research, are brought together in this volume. Each chapter focuses on a different aspect of bone loss and fragility with a fresh and stimulating perspective.

The Second Fifty Years

The Second Fifty Years PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309046815
Category : Medical
Languages : en
Pages : 345

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Book Description
Taking its title from the second 50 years of the human life span of about 100 years, this book presents wide-ranging and practical recommendations for health care providers, policymakers, and other sectors of society. These recommendations range from setting new national policies to changing the way elderly patients are interviewed in the doctor's office and from what exercises older persons should do to how city planners should design our urban environment. The bulk of this volume presents the latest research on 13 major health threats to the elderly, covering prevalence, impact on the older person's life, cost, and intervention. In addition, the authors provide a detailed analysis of why older people often do not receive the benefit of prevention programs.