Biological Basis of Sex Differences in Psychopharmacology PDF Download
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Author: Jo C. Neill
Publisher: Springer Science & Business Media
ISBN: 3642200060
Category : Medical
Languages : en
Pages : 262
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Book Description
Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.
Author: Jo C. Neill
Publisher: Springer Science & Business Media
ISBN: 3642200060
Category : Medical
Languages : en
Pages : 262
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Book Description
Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.
Author: Wim E. Crusio
Publisher: Cambridge University Press
ISBN: 1107355575
Category : Science
Languages : en
Pages : 361
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Book Description
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author: Susan Nolen-Hoeksema
Publisher: Stanford University Press
ISBN: 9780804716406
Category : Self-Help
Languages : en
Pages : 280
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Book Description
Women are twice as likely as men to experience protracted sadness, apathy, low self-esteem, and other symptoms of depression. How can we account for this sex difference? Several explanations have been proposed, some dating back many years. This book critically examines the evidence for each explanation in an attempt to discover what we do and do not know about sex differences in depression. It is a landmark review of the historical, theoretical and empirical approaches to sex differences in depression. Nolen-Hoeksema presents a fresh historical review, makes theoretical criticisms and offers clear and challenging avenues for future research and practical applications.
Author: David J. Kupfer
Publisher: American Psychiatric Pub
ISBN:
Category : Medical
Languages : en
Pages : 340
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Book Description
Produced as a partnership between the American Psychiatric Association and the National Institute of Mental Health, the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse, this thought-provoking collection of white papers: Examines nomenclature issues. Reviews genetic, brain imaging, postmortem, and animal model research and includes strategic insights for a new research agenda Outlines recent progress in developmental neuroscience, genetics, psychology, psychopathology, and epidemiology, focusing on the turbulent first two decades of life. Suggests a research agenda for personality disorders that uses a dimensional rather than the current categorical approach to diagnosis. Proposes a research agenda to evaluate the clinical utility and validity of adding relational disorders to DSM-IV. Reevaluates the relationship between mental disorders and disability, proposing that diagnosis and disability be uncoupled. Examines the importance of culture in psychopathology and the main cultural variables at play in the diagnostic process.
Author: Todd D. Gould
Publisher:
ISBN: 9781617793134
Category : Affective disorders
Languages : en
Pages :
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Book Description
Author: Jay Belsky
Publisher: Routledge
ISBN: 1317838130
Category : Psychology
Languages : en
Pages : 459
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Book Description
First published in 1987. This study records findings of a study group set up to explore a variety of issues related to attachment, including the predictive utility of Strange Situation assessments, the conditions under which insecurity is related to subsequent difficulties, the origins of individual differences in attachment security, and intervention strategies that might prove useful in ameliorating the developmental risks that appeared to be associated with insecure attachment relationships
Author: Dennis S. Charney
Publisher: Oxford University Press
ISBN: 019068142X
Category : Medical
Languages : en
Pages : 1025
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Book Description
In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030916785X
Category : Science
Languages : en
Pages : 223
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Book Description
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Author:
Publisher: Elsevier
ISBN: 0080861865
Category : Medical
Languages : en
Pages : 531
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Book Description
Sex Differences in the Brain
Author: Daniel Romer
Publisher: Oxford University Press
ISBN: 0198041802
Category : Psychology
Languages : en
Pages : 525
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Book Description
Recent advances in our understanding of the human brain suggest that adolescence is a unique period of development during which both environmental and genetic influences can leave a lasting impression. To advance the goal of integrating brain and prevention science, two areas of research which do not usually communicate with one another, the Annenberg Public Policy Center's Adolescent Risk Communication Institute held a conference with the purpose of producing an integrated volume on this interdisciplinary area. Presenters/chapter contributors were asked to address two questions: What neurodevelopmental processes in children and adolescents could be altered so that mental disorders might be prevented? And what interventions or life experiences might be able to introduce such changes? The book has a 5-part structure: biological and social universals in development; characteristics of brain and behavior in development; effects of early maltreatment and stress on brain development; effects of stress and other environmental influences during adolescence on brain development; and reversible orders of brain development. The twenty chapters include contributions from some of the most well-known researchers in the area.
