Author: Raymond F. Burk
Publisher: Springer
ISBN: 9781461225935
Category : Science
Languages : en
Pages : 221
Get Book Here
Book Description
Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health. Starting with investigations over 60 years ago into its role as a toxic agent in livestock disease, selenium studies have progressed rapidly with the application of tools from immunology and molecular biology. Selenium is now known to be important in human and animal nutrition, has been discovered as a structural component of so-called selenoproteins, and may play a number of physiological roles, ranging from cancer protection to hormone metabolism. Selenium in Biology and Human Health presents research syntheses on a range of topics involving selenium, written by specialists from around the world. It will be of interest to cell biologists and physiologists, nutritional scientists, and animal health researchers.
Author: Gary S. Banuelos
Publisher: CRC Press
ISBN: 0203771419
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
Selenium is arguably the naturally occurring trace element of greatest concern worldwide. In excessive amounts it can lead to toxicosis and teratogenesis in animals, while the impact of selenium deficiency can be even more significant. Contributors from 22 countries explored the connections and inter-relationships between selenium in the environmen
Author: Raymond F. Burk
Publisher: Springer Science & Business Media
ISBN: 1461225922
Category : Science
Languages : en
Pages : 214
Get Book Here
Book Description
Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health. Starting with investigations over 60 years ago into its role as a toxic agent in livestock disease, selenium studies have progressed rapidly with the application of tools from immunology and molecular biology. Selenium is now known to be important in human and animal nutrition, has been discovered as a structural component of so-called selenoproteins, and may play a number of physiological roles, ranging from cancer protection to hormone metabolism. Selenium in Biology and Human Health presents research syntheses on a range of topics involving selenium, written by specialists from around the world. It will be of interest to cell biologists and physiologists, nutritional scientists, and animal health researchers.
Author: Dolph L. Hatfield
Publisher: Springer Science & Business Media
ISBN: 1461516099
Category : Science
Languages : en
Pages : 329
Get Book Here
Book Description
As discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent. Further evidence points to a role of this element in reducing viral expression, in preventing heart disease, and other cardiovascular and muscle disorders, and in delaying the progression of AIDS in HIV infected patients. Selenium may also have a role in mammalian development, in male fertility, in immune function and in slowing the aging process. The mechanism by which selenium exerts its beneficial effects on health may be through selenium-containing proteins. Selenium is incorporated into protein as the amino acid selenocysteine. Selenocysteine utilizes a specific tRNA, a specific elongation factor, a specific set of signals, and the codeword, UGA, for its cotranslational insertion into protein. It is indeed the 21st naturally occurring amino acid to be incorporated into protein and marks the first and only expansion of the genetic code since the code was deciphered in the mid 1960s.
Author: Dolph L. Hatfield
Publisher: Springer Science & Business Media
ISBN: 1461410258
Category : Science
Languages : en
Pages : 596
Get Book Here
Book Description
Many health benefits have been attributed to selenium that include preventing various forms of cancer (e.g., colon cancer, prostate cancer, lung cancer and liver cancer), heart disease and other cardiovascular and muscle disorders, inhibiting viral expression, delaying the progression of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)-positive patients, slowing the aging process, and having roles in mammalian development, including male reproduction and immune function. The purpose of the book is the same as the first two volumes which is to bring an up to date status of current research in the rapidly developing selenium field centered around the health benefits attributed to this element and how this element makes its way into protein.
Author: Raymond F. Burk
Publisher: Springer
ISBN: 9780387940809
Category : Science
Languages : en
Pages : 221
Get Book Here
Book Description
Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health. Starting with investigations over 60 years ago into its role as a toxic agent in livestock disease, selenium studies have progressed rapidly with the application of tools from immunology and molecular biology. Selenium is now known to be important in human and animal nutrition, has been discovered as a structural component of so-called selenoproteins, and may play a number of physiological roles, ranging from cancer protection to hormone metabolism. Selenium in Biology and Human Health presents research syntheses on a range of topics involving selenium, written by specialists from around the world. It will be of interest to cell biologists and physiologists, nutritional scientists, and animal health researchers.
Author: Dolph L. Hatfield
Publisher: Springer
ISBN: 9780387338262
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This book examines the molecular biology of selenium and how this element makes its way into protein. The role of this element in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders is explored in the text. The Second Edition outlines discoveries since the book was first introduced in 2001. Chapter updates have been written by investigators who have made important contributions to the field.
Author: Catherine Méplan
Publisher: MDPI
ISBN: 3039361465
Category : Science
Languages : en
Pages : 170
Get Book Here
Book Description
“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches.
Author: Elizabeth A.H. Pilon-Smits
Publisher: Springer
ISBN: 3319562495
Category : Science
Languages : en
Pages : 326
Get Book Here
Book Description
This book covers many facets of plant selenium (Se) accumulation: molecular genetics, biochemistry, physiology, and ecological and evolutionary aspects. Broader impacts and applications of plant Se accumulation also receive attention. Plant Se accumulation is very relevant for environmental and human health. Selenium is both essential at low levels and toxic at high levels, and both Se deficiency and toxicity are problems worldwide. Selenium can positively affect crop productivity and nutritional value. Plants may also be used to clean up excess environmental Se. Selenium in plants has profound ecological impact, and likely contributes to Se movement in ecosystems and global Se cycling.
Author: Gary Bañuelos
Publisher: CRC Press
ISBN: 0429752148
Category : Technology & Engineering
Languages : en
Pages : 228
Get Book Here
Book Description
The biological importance of selenium has been firmly established by scientists for its intricate roles in various biochemical and physiological mechanisms related to animal and human health. To evaluate different facets of selenium in today’s complex environment and to provide a worldwide platform for multi-disciplinary selenium researchers, the 6th International Conference on Selenium in the Environment and Human Health was held from 27 to 30 October 2019 in Yangling/Xi’an, China. This proceedings volume brings together 103 extended abstracts prepared by contributors from academia, industry, and governmental agencies in 18 countries, including some most recent research findings among different selenium research disciplines from cell molecular and plant biology, geochemistry, biofortification, to environmental and health management. Selenium researchers worldwide provide extraordinary new knowledge on selenium in the peer-reviewed texts contained within this book.
