Secondary-Metabolite Biosynthesis and Metabolism PDF Download
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Author: American Chemical Society
Publisher: Springer Science & Business Media
ISBN: 9780306443091
Category : Medical
Languages : en
Pages : 410
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Book Description
Proceedings of an American Chemical Society symposium on Biosynthesis and Metabolism of Secondary Metabolite Natural Products, held April 1991, in Atlanta, Georgia. Bridging the gap between the fields of mechanistic bio-organic chemistry and biotechnology, contributions are in four main areas: antib
Author: American Chemical Society
Publisher: Springer Science & Business Media
ISBN: 9780306443091
Category : Medical
Languages : en
Pages : 410
Get Book Here
Book Description
Proceedings of an American Chemical Society symposium on Biosynthesis and Metabolism of Secondary Metabolite Natural Products, held April 1991, in Atlanta, Georgia. Bridging the gap between the fields of mechanistic bio-organic chemistry and biotechnology, contributions are in four main areas: antib
Author: R. B. Herbert
Publisher: Springer Science & Business Media
ISBN: 9400958331
Category : Science
Languages : en
Pages : 187
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Book Description
This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This account is primarily intended to be an introduction to the biosynthesis of secondary metabolites. I have also endeavoured, however, to make the book as comprehensive as possIble. This has meant that some of the material has had to be presented in abbrevi ated form. The abbreviated material is largely confined to particular sections of the book. The paragraphs marked with a dagger (t) can be omitted by the reader wishing to acquire a general introduction to the subject. A blend of the most significant and the most recent references is cited to provide the reader with ready access to the primary litera ture. This is clearly most necessary for the material presented in abbreviated form. Relevant reviews are also cited.
Author: R. Verpoorte
Publisher: Springer Science & Business Media
ISBN: 9401594236
Category : Science
Languages : en
Pages : 288
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Book Description
Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.
Author: G. Lancini
Publisher: Springer Science & Business Media
ISBN: 147579522X
Category : Science
Languages : en
Pages : 240
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Book Description
In response to the field's need for an introductory text, the authors have distilled the vast and scattered literature relating to the biotechnology of microbial secondary metabolites. General biology, biosynthesis, the search for novel metabolites, and techniques for strain improvement are all discussed to provide undergraduate and graduate students with a concise, readable overview of the field.
Author: Ramasamy Vijayakumar
Publisher: BoD – Books on Demand
ISBN: 1789236428
Category : Science
Languages : en
Pages : 149
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Book Description
This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.
Author: Nancy P. Keller
Publisher: Humana Press
ISBN: 9781627031219
Category : Science
Languages : en
Pages : 288
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Book Description
Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and molecular manipulation techniques has galvanized a revitalization of this field. Fungal Secondary Metabolism: Methods and Protocols is aimed at providing the key methodologies currently in use and necessary for accessing and exploiting the natural product information provided by the genomes of this large and varied kingdom. Written by active researchers in the field, the chapters deal with all the steps necessary, from optimization of fungal culture conditions for metabolite production, through rapid genome sequencing and bioinformatics, and genetic manipulations for functional analysis, to detection and testing of metabolites. In addition, chapters on basic science address approaches to the genetic regulation, protein biochemistry, and cellular localization of the biosynthetic pathways. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and hands-on, Fungal Secondary Metabolism: Methods and Protocols encourages new investigators to enter the field and expands upon the expertise and range of skills of those already researching fungal natural products.
Author: Mohamed Mahgoub Azooz
Publisher: John Wiley & Sons
ISBN: 1119081025
Category : Science
Languages : en
Pages : 361
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Book Description
The increase in global population, urbanization and industrialization is resulting in the conversion of cultivated land into wasteland. Providing food from these limited resources to an ever-increasing population is one of the biggest challenges that present agriculturalists and plant scientists are facing. Environmental stresses make this situation even graver. Plants on which mankind is directly or indirectly dependent exhibit various mechanisms for their survival. Adaptability of the plants to changing environment is a matter of concern for plant biologists trying to reach the goal of food security. Despite the induction of several tolerance mechanisms, sensitive plants often fail to withstand these environmental extremes. Using new technological approaches has become essential and imperative. Plant-Environment Interaction: Responses and Approaches to Mitigate Stress throws light on the changing environment and the sustainability of plants under these conditions. It contains the most up-to-date research and comprehensive detailed discussions in plant physiology, climate change, agronomy and forestry, sometimes from a molecular point of view, to convey in-depth understanding of the effects of environmental stress in plants, their responses to the environment, how to mitigate the negative effects and improve yield under stress. This edited volume is written by expert plant biologists from around the world, providing invaluable knowledge to graduate and undergraduate students in plant biochemistry, food chemistry, plant physiology, molecular biology, plant biotechnology, and environmental sciences. This book updates scientists and researchers with the very latest information and sustainable methods used for stress tolerance, which will also be of considerable interest to plant based companies and institutions concerned with the campaign of food security.
Author: Pieter S. Steyn
Publisher:
ISBN:
Category : Nature
Languages : en
Pages : 456
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Book Description
The Biosynthesis of Mycotoxins ...
Author: Simon Baumberg
Publisher: Springer Science & Business Media
ISBN: 1468459228
Category : Science
Languages : en
Pages : 318
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Book Description
The Streptomycetes are industrially widely used microorganisms due to their ability to produce numerous different chemical compounds. These show very varied effects upon other living systems, and result from profound and subtle biochemical and morphological differentiation during the streptomycete life cycle. It is therefore not surprising that research on the genetics of antibiotic biosynthesis and differentiation in this group is currently progressing rapidly in many countries. Intimately connected with the production of antibiotics is resistance to them; analysis of this is giving further information about the origin and evolution of this class of genes and their hypothesized spread among other microorganisms. Another interesting feature of the Streptomyces group is their mycelial growth. Also, their ecologically important utilization of high molecular weight compounds requires enzymes to be transported outside the cell to hydrolyze non-diffusible substrates. Finally, we have as yet limited understanding of the various mechanisms of genome rearrangement observed in some of these species; deletions and/or amplifications of enormous amounts of DNA can occur without seriously affecting the viability of the organism under laboratory conditions. The present volume, which includes contributions addressing the above subjects and others, originates from a meeting on "Genetics and Product Formation in Streptomyces" sponsored by the Federation of European Microbiological Societies in Erfurt on May 1-6 1990. Compared to previous ones of this kind held in 1979, 1983 and 1987 in Weimar, one can point to impressive progress in the study and applications of Streptomyces genetics.
Author: Alan Crozier
Publisher: John Wiley & Sons
ISBN: 0470994134
Category : Technology & Engineering
Languages : en
Pages : 384
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Book Description
Plant secondary metabolites have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies. The subject is multi-disciplinary with chemists, biochemists and plant scientists all contributing to our current understanding. In recent years there has been an upsurge in interest from other disciplines, related to the realisation that secondary metabolites are dietary components that may have a considerable impact on human health, and to the development of gene technology that permits modulation of the contents of desirable and undesirable components. Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet addresses this wider interest by covering the main groups of natural products from a chemical and biosynthetic perspective with illustrations of how genetic engineering can be applied to manipulate levels of secondary metabolites of economic value as well as those of potential importance in diet and health. These descriptive chapters are augmented by chapters showing where these products are found in the diet, how they are metabolised and reviewing the evidence for their beneficial bioactivity.
