Science Is Not A Quiet Life: Unravelling The Atomic Mechanism Of Haemoglobin PDF Download
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Author: Max F Perutz
Publisher: World Scientific
ISBN: 9814498513
Category : Science
Languages : en
Pages : 659
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Book Description
Linus Pauling called haemoglobin the most interesting and important of molecules. This important volume shows how X-ray crystallography was used to determine its bewilderingly complex atomic structure and to unravel the stereochemical mechanisms of its respiratory functions. It introduces isomorphous replacement with heavy atoms which led to the first protein structures, haemoglobin and its simpler relative myoglobin. Later papers deal with the stereochemistry of the cooperative effects of haemoglobin, with the relationships between the structures and impaired functions of abnormal haemoglobin, with species adaptation of haemoglobin, and with its action as a drug receptor and as an oxygen sensor. The final papers deal with amino acid repeats which act as polar zippers and their role in certain inherited neurodegenerative diseases.
Author: Max F Perutz
Publisher: World Scientific
ISBN: 9814498513
Category : Science
Languages : en
Pages : 659
Get Book Here
Book Description
Linus Pauling called haemoglobin the most interesting and important of molecules. This important volume shows how X-ray crystallography was used to determine its bewilderingly complex atomic structure and to unravel the stereochemical mechanisms of its respiratory functions. It introduces isomorphous replacement with heavy atoms which led to the first protein structures, haemoglobin and its simpler relative myoglobin. Later papers deal with the stereochemistry of the cooperative effects of haemoglobin, with the relationships between the structures and impaired functions of abnormal haemoglobin, with species adaptation of haemoglobin, and with its action as a drug receptor and as an oxygen sensor. The final papers deal with amino acid repeats which act as polar zippers and their role in certain inherited neurodegenerative diseases.
Author: Max F. Perutz
Publisher: World Scientific
ISBN: 9789810227746
Category : Science
Languages : en
Pages : 664
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Book Description
"Max Perutz does for haemoglobin in this book what Primo Levi did for the Periodic Table ... The book is far from dry, however, Perutz beginning each chapter with fascinating historical & anecdotal background."
Author: Max F. Perutz
Publisher: Oxford University Press, USA
ISBN: 9780198590279
Category : Biography & Autobiography
Languages : en
Pages : 388
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Book Description
This collection of essays from Nobel Laureate Max Perutz explores a wide range of scientific and personal topics with insight and lucidity. It includes lively anecdotes about key figures in 20th-century science.
Author: Beryl Bainbridge
Publisher: Open Road Media
ISBN: 1504039912
Category : Fiction
Languages : en
Pages : 130
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Book Description
The tragicomic tale of a dysfunctional middle-class family in postwar England from the award-winning author of Injury Time. Though the Second World War has ended, times are anything but peaceful for seventeen-year-old Alan. His father, an entrepreneur who was once able to provide the family with a comfortable life, is now struggling to put food on the table. Meanwhile, Alan’s mother dresses as if money is plentiful and spends all her time avoiding her husband, indulging in the escapism of romance novels, and engaging in real-world love affairs. And as if a household struck by poverty and marital trouble isn’t enough, Alan’s bohemian sister, Madge, has been sneaking off into the sand dunes for lusty rendezvous with a German POW. All Alan wants is for his sister to stop cavorting around and driving their father mad—and for a pretty choir girl named Janet to notice him. But the more he wishes for a normal life, the more chaotic it becomes. Everyone in his family is hiding something, not only from one another but also from themselves. And they’re all desperately clinging to something that is inevitably falling apart. Award-winning British author Beryl Bainbridge has a keen eye for the dark humor that lurks in misery and a knack for illuminating the emotional rubble of postwar England. A Quiet Life is an entertaining family drama that is at once a quick read and a lasting portrait of twentieth-century life.
Author: Lynn Cullen
Publisher: Penguin
ISBN: 0698402553
Category : Juvenile Fiction
Languages : en
Pages : 36
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Book Description
Based on the true story behind Gilbert Stuart's famous portraits of Washington, this funny historical read will leave rascals, ruffians, and troublemakers of all ages laughing. Charlotte, James, and baby John have promised to be on their very best behavior for when George Washington comes to have his portrait painted by their father, Gilbert Stuart. But, it seems like every time George Washington comes to visit, Charlotte has to write another apology letter, even when they try to follow George Washington’s Rules of Good Behavior. If these whippersnappers want any dessert, they are going to have to learn some manners—and fast! What results is a hilarious chain of events, a giant mess…and a painting that will be remembered for centuries to come.
Author: Francis Collins
Publisher: Simon and Schuster
ISBN: 1847396151
Category : Science
Languages : en
Pages : 227
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Book Description
Dr Francis S. Collins, head of the Human Genome Project, is one of the world's leading scientists, working at the cutting edge of the study of DNA, the code of life. Yet he is also a man of unshakable faith in God. How does he reconcile the seemingly unreconcilable? In THE LANGUAGE OF GOD he explains his own journey from atheism to faith, and then takes the reader on a stunning tour of modern science to show that physics, chemistry and biology -- indeed, reason itself -- are not incompatible with belief. His book is essential reading for anyone who wonders about the deepest questions of all: why are we here? How did we get here? And what does life mean?
Author:
Publisher: American Philosophical Society
ISBN: 9781422372883
Category :
Languages : en
Pages : 116
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Book Description
Author: Ethan Joella
Publisher: Simon and Schuster
ISBN: 198219099X
Category : Fiction
Languages : en
Pages : 320
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Book Description
From the author of A Little Hope—a Read with Jenna Bonus Pick—comes another “heartwarming, character-driven” (Booklist) life-affirming novel about three individuals whose lives intersect in unforeseen ways. Set in a close-knit suburb in the grip of winter, A Quiet Life follows three people grappling with loss and finding a tender wisdom in their grief. Chuck Ayers used to look forward to nothing so much as his annual trip to Hilton Head with his wife, Cat—that yearly taste of relaxation they’d become accustomed to after a lifetime of working and raising two children. Now, just months after Cat’s death, Chuck finds that he can’t let go of her belongings—her favorite towel, the sketchbooks in her desk drawer—as he struggles to pack for a trip he can’t imagine taking without her. Ella Burke delivers morning newspapers and works at a bridal shop to fill her days while she anxiously awaits news—any piece of information—about her missing daughter. Ella adjusts to life in a new apartment and answers every call on her phone, hoping her daughter will reach out. After the sudden death of her father, Kirsten Bonato set aside her veterinary school aspirations, finding comfort in the steady routine of working at an animal shelter. But as time passes, old dreams and new romantic interests begin to surface—and Kirsten finds herself at another crossroads. In this beautiful and profoundly moving novel, three parallel narratives converge in poignant and unexpected ways, as each character bravely presses onward, trying to recover something they have lost. Emotionally riveting and infused with hope, “the soothing tone and warm worldview of this grown-up bedtime story will be good for what ails you” (Kirkus Reviews).
Author: Ethan Joella
Publisher: Simon and Schuster
ISBN: 1982171219
Category : Fiction
Languages : en
Pages : 320
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Book Description
A Read with Jenna Bonus Selection An “immersive…illuminating” (Booklist) and life-affirming novel following the residents of an idyllic Connecticut town over the course of a year, A Little Hope explores the intertwining lives of a dozen neighbors as they confront everyday desires and fears: a lost love, a stalled career, an illness, and a betrayal. Freddie and Greg Tyler seem to have it all: a comfortable home, a beautiful young daughter, a bond that feels unbreakable. But when Greg is diagnosed with a rare and aggressive form of cancer, the sense of certainty they once knew evaporates. Throughout their town, friends and neighbors face the most difficult of life’s challenges and are figuring out how to survive thanks to love, grace, and hope. “A quietly powerful portrait of small-town life…told with wisdom and tenderness” (Mary Beth Keane, author of Ask Again, Yes) A Little Hope is a deeply resonant debut that immerses the reader in a community and celebrates the importance of small moments of connection.
Author: Michael Strevens
Publisher: Liveright Publishing
ISBN: 1631491385
Category : Science
Languages : en
Pages : 368
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Book Description
“The Knowledge Machine is the most stunningly illuminating book of the last several decades regarding the all-important scientific enterprise.” —Rebecca Newberger Goldstein, author of Plato at the Googleplex A paradigm-shifting work, The Knowledge Machine revolutionizes our understanding of the origins and structure of science. • Why is science so powerful? • Why did it take so long—two thousand years after the invention of philosophy and mathematics—for the human race to start using science to learn the secrets of the universe? In a groundbreaking work that blends science, philosophy, and history, leading philosopher of science Michael Strevens answers these challenging questions, showing how science came about only once thinkers stumbled upon the astonishing idea that scientific breakthroughs could be accomplished by breaking the rules of logical argument. Like such classic works as Karl Popper’s The Logic of Scientific Discovery and Thomas Kuhn’s The Structure of Scientific Revolutions, The Knowledge Machine grapples with the meaning and origins of science, using a plethora of vivid historical examples to demonstrate that scientists willfully ignore religion, theoretical beauty, and even philosophy to embrace a constricted code of argument whose very narrowness channels unprecedented energy into empirical observation and experimentation. Strevens calls this scientific code the iron rule of explanation, and reveals the way in which the rule, precisely because it is unreasonably close-minded, overcomes individual prejudices to lead humanity inexorably toward the secrets of nature. “With a mixture of philosophical and historical argument, and written in an engrossing style” (Alan Ryan), The Knowledge Machine provides captivating portraits of some of the greatest luminaries in science’s history, including Isaac Newton, the chief architect of modern science and its foundational theories of motion and gravitation; William Whewell, perhaps the greatest philosopher-scientist of the early nineteenth century; and Murray Gell-Mann, discoverer of the quark. Today, Strevens argues, in the face of threats from a changing climate and global pandemics, the idiosyncratic but highly effective scientific knowledge machine must be protected from politicians, commercial interests, and even scientists themselves who seek to open it up, to make it less narrow and more rational—and thus to undermine its devotedly empirical search for truth. Rich with illuminating and often delightfully quirky illustrations, The Knowledge Machine, written in a winningly accessible style that belies the import of its revisionist and groundbreaking concepts, radically reframes much of what we thought we knew about the origins of the modern world.
