Salmonella Mutagenicity Tests: II PDF Download
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Author:
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ISBN:
Category :
Languages : en
Pages : 119
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Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 119
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Author:
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Category :
Languages : en
Pages :
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Author: Ludwig Hothorn
Publisher: Springer Science & Business Media
ISBN: 364248736X
Category : Medical
Languages : en
Pages : 158
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Book Description
This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The papers deal with the biostatistical evaluation of the commonly used toxicological assays, i.e. mutagenicity, long-term carcinogenicity, embryotoxicity and chronic toxicity assays. The biological background is considered in detail, and most of the related statistical approaches described. In five overview papers, the present state of the art of the related topics is given, while in several contributed papers new approaches are discussed. The most important features are: - A new view on the per-litter analysis problem in em- bryotoxicity assays. - A highly sophisticated treatment of the so-called muta-tox problem in mutagenicity assays. - A detailed discussion of the multiplicity problem based on the closed testing procedure. This volume provides readers with an overview of modern biostatistical methods for several toxicological assays and is in part intended for direct, practical use.
Author:
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Category :
Languages : en
Pages :
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Author: B.J. Kilbey
Publisher: Elsevier
ISBN: 0444600981
Category : Medical
Languages : en
Pages : 876
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The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
Author: David J. Kirkland
Publisher: Cambridge University Press
ISBN: 9780521048149
Category : Medical
Languages : en
Pages : 316
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Book Description
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds.
Author: Errol Zeiger
Publisher:
ISBN:
Category : Mutagenicity testing
Languages : en
Pages : 109
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Author:
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ISBN:
Category :
Languages : en
Pages :
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Author: Errol Zeiger
Publisher:
ISBN:
Category : Chemical mutagenesis
Languages : en
Pages : 158
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Author: Kristien Mortelmans
Publisher:
ISBN:
Category : Mutagenicity testing
Languages : en
Pages :
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