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Author: American Institute for Cancer Research
Publisher: Springer Science & Business Media
ISBN: 1461525101
Category : Medical
Languages : en
Pages : 190
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Book Description
The fourth annual American Institute for Cancer Research (AICR) conference on diet, nutrition and cancer was held at the L'Enfant Plaza Hotel in Washington, D. C. , September 2~3, 1993. In keeping with present concerns and in line with current trends, the theme was "Diet and Breast Cancer. " This proceedings volume is comprised of chapters from the platform presentations of the two day conference and abstracts from the poster session held at the end of the first day. Experimentally, there is sufficient evidence to support a relationship between dietary fat and the risk of breast cancer. A meta-analysis was provided by data from 114 experiments with over 10,000 animals, divided into groups fed ad libitum on diets with different levels or sources of fat, or different levels of energy restriction. This exercise suggested that linoleic acid was a major determinant of mammary tumor development but that other fatty acids also enhanced mammary tumor development in animals. However, as mentioned by several speakers, results from epidemiological studies often are conflicting, thus leading to confusion among both health professionals and the public. Surveys of specific populations which have migrated from countries with low breast cancer rates to those with higher rates are often some of the most compelling studies with respect to a high fat diet-breast cancer association. Nonetheless, various cohort and prospective studies, some quite large, did not appear to show a relationship between consumption of fat (any type) and breast cancer.
Author: American Institute for Cancer Research
Publisher: Springer Science & Business Media
ISBN: 1461525101
Category : Medical
Languages : en
Pages : 190
Get Book Here
Book Description
The fourth annual American Institute for Cancer Research (AICR) conference on diet, nutrition and cancer was held at the L'Enfant Plaza Hotel in Washington, D. C. , September 2~3, 1993. In keeping with present concerns and in line with current trends, the theme was "Diet and Breast Cancer. " This proceedings volume is comprised of chapters from the platform presentations of the two day conference and abstracts from the poster session held at the end of the first day. Experimentally, there is sufficient evidence to support a relationship between dietary fat and the risk of breast cancer. A meta-analysis was provided by data from 114 experiments with over 10,000 animals, divided into groups fed ad libitum on diets with different levels or sources of fat, or different levels of energy restriction. This exercise suggested that linoleic acid was a major determinant of mammary tumor development but that other fatty acids also enhanced mammary tumor development in animals. However, as mentioned by several speakers, results from epidemiological studies often are conflicting, thus leading to confusion among both health professionals and the public. Surveys of specific populations which have migrated from countries with low breast cancer rates to those with higher rates are often some of the most compelling studies with respect to a high fat diet-breast cancer association. Nonetheless, various cohort and prospective studies, some quite large, did not appear to show a relationship between consumption of fat (any type) and breast cancer.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Aamir Ahmad
Publisher: Springer Nature
ISBN: 3030203018
Category : Medical
Languages : en
Pages : 427
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Book Description
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Author: Dr. Nanda Rajaneesh
Publisher: Notion Press
ISBN: 1685234534
Category : Medical
Languages : en
Pages : 141
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Book Description
“Why me?” is a question that is frequently asked by breast cancer patients. While the easiest answer is bad luck; it is well known that the disease is multifactorial, with all these factors being interrelated. Although some of these factors are well-established, a vast majority of them remain unexplored. This ignited a desire to delve into the existing published literature and utilise personal clinical experience to identify all possible risk factors in breast cancer; among which easily manageable problems such as vitamin D, B12 deficiency, excessive weight gain and sedentary practices, consumption of hormones-enriched milk products and processed foods as well as a weak immune system have proven to cause a massive hormonal imbalance which has a huge impact on breast cancer development. This book highlights the correlation of such factors and the risk of acquiring breast cancer and focuses on utilising this knowledge to not only prevent new breast cancers in the general population but also prevent recurrences among existing breast cancer patients.
Author: Lida A. Mina
Publisher: Springer
ISBN: 3319194372
Category : Medical
Languages : en
Pages : 108
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Book Description
Uniquely designed for oncologists and general practitioners, this book offers clinicians comprehensive guidelines when dealing with women at high risk for breast cancer. Written by experts in the field on the cutting edge of this research, the following questions will be answered for the reader by the end of the book: · Who is at elevated risk for breast cancer? · Who should be genetically screened? · When and how often should we obtain imaging? · What type of imaging is adequate? · What medications are available for prevention? · When is surgical intervention appropriate? · What lifestyle changes should be implemented to prevent this disaster? With one in eight women likely to contract breast cancer in her lifetime, the significance of identifying and managing the high-risk patient is evident. Breakthroughs in the identification of genes associated with breast carcinoma, particularly BRCA1 and 2, as well as other risk factors, influence not only how patients are screened, but also how they are treated. Breast Cancer Prevention and Treatment provides a guided approach to prevention of breast cancer in women at elevated risk for this malignancy.
Author: Ahmedin Jemal
Publisher:
ISBN: 9781604432282
Category : Cancer
Languages : en
Pages : 0
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Book Description
This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.
Author: Deborah A. Dawson
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 68
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Book Description
Author: Marlene B. Goldman
Publisher: Academic Press
ISBN: 0123849799
Category : Social Science
Languages : en
Pages : 1616
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Book Description
Women and Health is a comprehensive reference that addresses health issues affecting women of all ages — from adolescence through maturity. It goes far beyond other books on this topic, which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. In this second edition of Women and Health, chapters thoughtfully explore the current state of women’s health and health care, including the influences of sex and gender on the occurrence of a wide variety of diseases and conditions. All chapters have been extensively updated and emphasize the epidemiology of the condition — the etiology, occurrence, primary and secondary prevention (screening), risk factors, surveillance, changing trends over time, and critical analysis of the diagnostic and treatment options and controversies. Treatment sections in each chapter have been expanded to create a stronger dialogue between epidemiologists and women's health practitioners. Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of women’s health issues, as opposed to searching through thousands of journal articles Provides a common language for epidemiologists, public health practitioners, and women’s health specialists to discuss the behavioral, cultural, and biological determinants of women’s health Researchers and medical specialists will learn how the gender-specific risks and features of one organ system’s diseases affect the health of other organ systems For example: Hormone replacement therapy used to treat imbalance within the endocrine system is also being used to prevent and treat cardiovascular disease; Drugs developed for type 2 diabetes are now being used in chemoprevention Orients the non-gerontologist about the importance of considering the entire life cycle of women within research designs and treatment plans Professors teaching courses in women’s health will use slides and additional materials to structure lectures/courses; students will use slides as a unique resource to study for exams
Author: Robert Eugene Gramling
Publisher:
ISBN:
Category :
Languages : en
Pages : 230
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Book Description
Abstract: Breast cancer represents a major public health burden in the United States and known risk factors only explain half of the risk for developing the disease. This dissertation comprises three studies designed to improve understanding of factors that influence breast cancer risk among postmenopausal women. Study One examines the relation between systemic inflammation, as measured by white blood cell count, and the risk of invasive breast cancer. During a mean follow-up period of 5.6 years, we observed a null relation among the 16,608 participants in the Women's Health Initiative Clinical Trial of hormone replacement therapy (HRWBC Quartile 4 v Quartiles 1-3 = 1.06, 95% CI = 0.83, 1.35). Study Two examines the degree to which familial predisposition interacts with hormone replacement therapy on the occurrence of invasive breast cancer. Among the same trial participants as Study One, we observed a negligible departure from the additive effects of each factor taken separately (Interaction Contrast = 0.002; 95% CI = -0.014, 0.018). Study Three investigates whether women's adherence to a set of breast cancer preventive behaviors decreases the rate of breast cancers that are attributable to a later-onset family history (i.e. having a 1st degree relative diagnosed with breast cancer after the age of 45 years). Among 85,644 women enrolled in the Women's Health Initiative Observational Study, we found no evidence to support such an interaction (Interaction Contrast = 0.00014; 95% CI = -0.00359, 0.00388).
Author: Edward R. Sauter
Publisher: Springer Science & Business Media
ISBN: 0387875832
Category : Medical
Languages : en
Pages : 251
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Book Description
While many comprehensive texts have been written on the treatment of breast cancer, the most common cancer among women, there are relatively few which cover in depth the prevention and early detection of the disease. The goal of this work is to present what experts in the ?eld feel is the current knowledge and future direction of breast cancer prevention and early detection. We begin Part I of the book with a review of risk factors, both genetic and environmental. We next review progress in the use of chemoprevention. Notably, chemoprevention risk reduction studies have led to FDA approval of two medications which measurably reduce disease incidence among women at increased risk, although with some risk of treatment related side effects. Newer agents in the pipeline, which may also reduce risk among normal risk women, are also discussed. Surgical risk reducing strategies complete the section on prevention, including both the bene?ts and downsides to this more aggressive approach. Even with aggressive prevention strategies, some women will develop breast cancer. For these women, early detection is critical to minimize disease spread and maximize long term survival. Part II of this book reviews current and upcoming approaches to early detection. Imaging strategies, including mammography, breast ultrasound, MRI, and PET imaging are reviewed. The potential for molecular tumor targeting to detect disease prior to the formation of a mass visible by anatomic imaging is presented.
