REGULATORY MECHANISMS FOR PROTEIN SYNTHESIS IN MAMMALIAN CELLS- PROCEEDINGS OF THE 3RD KETTERING SYMPOSIUM- REGULATION OF PROTEIN SYNTHESIS. PDF Download
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Author:
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Category :
Languages : en
Pages :
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Author:
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ISBN:
Category :
Languages : en
Pages :
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Author: Anthony Gordan San Pietro
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 506
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Author: Marvin L. Lamborg
Publisher:
ISBN:
Category :
Languages : en
Pages : 477
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Author: Daniel Atkinson
Publisher: Elsevier
ISBN: 0323162207
Category : Nature
Languages : en
Pages : 487
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Book Description
Modulation of Protein Function, Volume XIII, presents the proceedings of the ICN-UCLA Symposium on Molecular and Cellular Biology held in Keystone, Colorado, from February 25-March 2, 1979. The symposium aimed to bring together workers from several fields, all of which deal with the modulation of protein function. The discussion of representative metabolic control systems, ranging from single enzyme responses to complex regulatory cascades, and the control of photosynthesis and of protein synthesis and enzyme inactivation, dealt with the general topic at perhaps its most fundamental cellular level. Modulations and conformational changes in proteins that underlie higher-level interactions, such as those involved in cyclic nucleotide function, sensing and chemotactic response to foreign materials, and the complement system, were also described. Two talks dealt with potential clinical relevance of phenomena of the types described by other participants. The book is organized into nine parts with papers covering the following topics: modulation of enzymes of intermediary metabolism (Part I); modulation and inactivation (Part II); photosynthesis and storage polysaccharides (Part III); cascade systems (Part IV); protein phosphorylation (Part V); methylation in chemotaxis (Part VI); cyclic GMP and cyclic CMP (Part VII); protein synthesis (Part VIII); and clinical implications (IX).
Author: Anthony San Pietro
Publisher:
ISBN:
Category :
Languages : en
Pages : 477
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Author:
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Category : Biological control systems
Languages : en
Pages : 477
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Book Description
Author: Robert E. Rhoads
Publisher: Springer Science & Business Media
ISBN: 364256688X
Category : Science
Languages : en
Pages : 208
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Book Description
The articles in the present volume are by major contributors to our under standing of signaling pathways affecting protein synthesis. They focus pri marily on two extracellular anabolic signals, although others are included as well. Insulin is one of the best-studied extracellular regulators of protein syn thesis. Several of the known pathways for regulation of protein synthesis were elucidated using insulin-dependent systems. Regulation of protein synthesis by amino acids, by contrast, is an emerging field that has recently received a great deal of attention. The dual role of amino acids as substrates for protein syn thesis and regulators of the overall process has only recently been recognized. Since amino acids serve as precursors for proteins, one might expect that with holding an essential amino acid would inhibit the elongation phase. Surpris ingly, research has shown that it is the initiation phase of protein synthesis that is restricted during amino acid starvation. Understanding the mechanisms by which the biosynthesis of proteins is reg ulated is important for several reasons. Protein synthesis consumes a major portion of the cellular ATP that is generated. Therefore, small changes in protein synthesis can have great consequences for cellular energy metabolism. Translation is also a major site for control of gene expression, since messenger RNAs differ widely in translational efficiency, and changes to the protein syn thesis machinery can differentially affect recruitment of individual mRNAs.
Author: Sung-Cheng Huang
Publisher:
ISBN:
Category : Proteins
Languages : en
Pages : 142
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Author: Stanley D. Wainwright
Publisher: New York : Columbia University Press
ISBN:
Category : Cell differentiation
Languages : en
Pages : 566
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Author: S. D. Wainwright
Publisher:
ISBN: 9780835790628
Category :
Languages : en
Pages : 560
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