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Author: Attila Gacser
Publisher: Frontiers Media SA
ISBN: 2889450627
Category :
Languages : en
Pages : 150
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Book Description
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
Author: Attila Gacser
Publisher: Frontiers Media SA
ISBN: 2889450627
Category :
Languages : en
Pages : 150
Get Book Here
Book Description
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
Author: Oliver Kurzai
Publisher: Springer
ISBN: 9783642394317
Category : Medical
Languages : en
Pages : 0
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Book Description
Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease.
Author: Sabine Fillinger
Publisher: Springer
ISBN: 3319233718
Category : Science
Languages : en
Pages : 488
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Book Description
The fungal genus Botrytis is the focus of intensive scientific research worldwide. The complex interactions between this pathogen and the plants it infects and the economic importance of the diseases caused by Botrytis (principally grey mould) on more than 1400 species of cultivated plants pre- and post-harvest, render this pathogen of particular interest to farmers, advisers, students and researchers in many fields worldwide. This 20-chapter book is a comprehensive treatise covering the rapidly developing science of Botrytis and reflecting the major developments in studies of this fungus. It will serve as a source of general information for specialists in agriculture and horticulture, and also for students and scientists interested in the biology of this fascinating, multifaceted phytopathogenic fungal species.
Author: Héctor M. Mora-Montes
Publisher: Springer
ISBN: 3319641131
Category : Science
Languages : en
Pages : 431
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Book Description
Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system. The mortality and morbidity rates associated to mycosis are progressively rising simply because some of these diseases are still neglected by health-care workers and due to the changing sensitivity to antifungal drugs displayed by these organisms. In this book, both researchers and clinicians working in the medical mycology field explore the most recent literature about specific mycosis; placing in one concise chapter thoroughly revisions of the current knowledge on virulence factors, recognition by immune cells, immunoevasion, epidemiology, new diagnosis trends and therapeutics. This book is recommended to researchers, physicians and students interested in medical mycology.
Author: Salomé LeibundGut-Landmann
Publisher: Frontiers Media SA
ISBN: 288966645X
Category : Science
Languages : en
Pages : 154
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Book Description
Author: Gioconda San-Blas
Publisher:
ISBN: 9781913652135
Category :
Languages : en
Pages :
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Book Description
In this book a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. Essential reading for everyone with an interest in pathogenic.
Author: Archana Singh
Publisher: Springer
ISBN: 9811073716
Category : Science
Languages : en
Pages : 367
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Book Description
The book offers an integrated overview of plant–pathogen interactions. It discusses all the steps in the pathway, from the microbe–host-cell interface and the plant’s recognition of the microbe to the plant’s defense response and biochemical alterations to achieve tolerance / resistance. It also sheds light on the classes of pathogens (bacteria, fungus and viruses); effector molecules, such as PAMPs; receptor molecules like PRRs and NBS-LRR proteins; signaling components like MAPKs; regulatory molecules, such as phytohormones and miRNA; transcription factors, such as WRKY; defense-related proteins such as PR-proteins; and defensive metabolites like secondary metabolites. In addition, it examines the role of post-genomics, high-throughput technology (transcriptomics and proteomics) in studying pathogen outbreaks causing crop losses in a number of plants. Providing a comprehensive picture of plant-pathogen interaction, the updated information included in this book is valuable for all those involved in crop improvement.
Author: Fernando E. Vega
Publisher: Oxford University Press
ISBN: 0195166523
Category : Science
Languages : en
Pages : 352
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Book Description
There is an increasing interest in using fungi as bio control agents for insect pests in agricultural systems, and also a growing interest in the basic biology of insect-fungal associations from the perspective of parasitism, symbiosis and infection. This title covers topics in this field, incorporating new molecular techniques wherever possible.
Author: Richard Robert Bélanger
Publisher: American Phytopathological Society
ISBN:
Category : Science
Languages : en
Pages : 314
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Book Description
"Chapters within "The Fungi" bring up to date the nomenclature and classification of species, accurately reflecting the phylogeny of the fungi. An entire chapter is dedicated to the taxonomy of the powdery mildew fungi providing a new and reliable international source for all mycologists and plant pathologists. Convenient reference to both 'old' and 'new' names throughout the book will facilitate understanding and accelerate transition towards general use of the new taxonomy and nomenclature."--pub. desc.
Author: Robert Wyngaert
Publisher: Amanda Lynn Petrin
ISBN: 1989950345
Category : Biography & Autobiography
Languages : en
Pages : 211
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Book Description
Robert Wyngaert is the fourth of five children, born and raised as a Belgian immigrant on the South Shore of Montreal. At nine years old, he is kicked out of school and forced to make his way in the world through working odd jobs and eventually building up a career. The day before his 1958 wedding, the stable, well-paying job he has worked his way up to lays him off, leaving him back at square one. Unbelievable but True is Robert’s story, from his humble beginnings to his constant drive for financial security and to find meaning in his life. From working three jobs at once to support his wife and three children, to building apartment buildings, a restaurant, and a campground, this book shares his achievements, and his struggles, on his way to happiness and success.
