Recent advancements in modeling and simulations of ion channels

Recent advancements in modeling and simulations of ion channels PDF Author: Simone Furini
Publisher: Frontiers Media SA
ISBN: 2832509541
Category : Science
Languages : en
Pages : 142

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Recent advancements in modeling and simulations of ion channels

Recent advancements in modeling and simulations of ion channels PDF Author: Simone Furini
Publisher: Frontiers Media SA
ISBN: 2832509541
Category : Science
Languages : en
Pages : 142

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Book Description


Recent advancements in modeling and simulations of ion channels

Recent advancements in modeling and simulations of ion channels PDF Author: Deborah Verran
Publisher: Frontiers Media SA
ISBN: 283250700X
Category : Science
Languages : en
Pages : 85

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Trafficking of Cardiac Ion Channels

Trafficking of Cardiac Ion Channels PDF Author: Marcel Verges
Publisher: MDPI
ISBN: 3039434721
Category : Science
Languages : en
Pages : 156

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Book Description
Protein sorting and trafficking are regulated by well-conserved mechanisms. These allow a distinctive set of resident proteins to be present in the correct subcellular organelle, which is required for proper cell functioning. Voltage-gated ion channels, as responsible for cardiomyocyte action potential, must be properly localized. They participate in cell excitability and electrical coupling, ensuring uninterrupted and rhythmic heart beating. Ion channel complexes comprise one or more pore-forming α subunits, associated β subunits, and additional proteins. Channel localization and function are regulated by the β subunits and associated proteins, such as cytoskeletal elements, cell-adhesion molecules, and adaptors. These influence protein targeting, anchoring, and retention in specific surface domains along the cardiomyocyte sarcolemma, such as intercalated discs, T-tubules, or the lateral membrane. Alterations in ion channel trafficking are the cause of channelopathies associated with inherited arrhythmias leading to sudden death. An outstanding question is how these molecular alterations lead to disease. In this volume, scientists share their vision to understand how cardiac ion channel trafficking is regulated and how it may become altered, leading to channelopathies that often turn into deadly arrhythmias. Data generated can be translated to a clinical context, hopefully turning into approaches to help prevention and treatment, which is of utmost importance, both medically and socially.

Liposomes, Lipid Bilayers and Model Membranes

Liposomes, Lipid Bilayers and Model Membranes PDF Author: Georg Pabst
Publisher: CRC Press
ISBN: 146650711X
Category : Medical
Languages : en
Pages : 470

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Book Description
As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evo

Ion Channels—Advances in Research and Application: 2012 Edition

Ion Channels—Advances in Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1464993408
Category : Science
Languages : en
Pages : 459

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Book Description
Ion Channels—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ion Channels. The editors have built Ion Channels—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ion Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ion Channels—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Recent Advances in Cardiotoxicity Testing

Recent Advances in Cardiotoxicity Testing PDF Author: Tamer M. A. Mohamed
Publisher: Frontiers Media SA
ISBN: 2889719545
Category : Science
Languages : en
Pages : 142

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Book Description


Advances in Planar Lipid Bilayers and Liposomes

Advances in Planar Lipid Bilayers and Liposomes PDF Author: A. Ottova-Leitmannova
Publisher: Gulf Professional Publishing
ISBN: 9780123694539
Category : Mathematics
Languages : en
Pages : 348

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Book Description
The lipid bilayer is central to life, as all living organisms possess a lipid bilayer structure, thereby underlying the lipid bilayer principle of biomembranes. The lipid bilayer principle and its applications are the main theme of this new book series. This new series on bilayer lipid membranes (BLMs and liposomes) include invited chapters on a broad range of topics, from theoretical investigations, specific studies, experimental methods, to practical applications. Written for newcomers, experienced scientists, and those who are not familiar with these specific research areas, the Series covers all aspects of lipid bilayer investigations, both fundamental and applied. * Covers a broad range of topics ranging from theoretical research, specific studies, experimental methods, to practical applications * Authoritative timely reviews by experts in this field * Indispensable source of information for new scientists

Molecular Modeling and Simulation: An Interdisciplinary Guide

Molecular Modeling and Simulation: An Interdisciplinary Guide PDF Author: Tamar Schlick
Publisher: Springer Science & Business Media
ISBN: 1441963510
Category : Mathematics
Languages : en
Pages : 757

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Book Description
Very broad overview of the field intended for an interdisciplinary audience; Lively discussion of current challenges written in a colloquial style; Author is a rising star in this discipline; Suitably accessible for beginners and suitably rigorous for experts; Features extensive four-color illustrations; Appendices featuring homework assignments and reading lists complement the material in the main text

Membrane Glycoproteins—Advances in Research and Application: 2012 Edition

Membrane Glycoproteins—Advances in Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1464996571
Category : Science
Languages : en
Pages : 248

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Book Description
Membrane Glycoproteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Membrane Glycoproteins. The editors have built Membrane Glycoproteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Membrane Glycoproteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Membrane Glycoproteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Membrane Transport Proteins: Advances in Research and Application: 2011 Edition

Membrane Transport Proteins: Advances in Research and Application: 2011 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 146492631X
Category : Science
Languages : en
Pages : 168

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Book Description
Membrane Transport Proteins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Membrane Transport Proteins. The editors have built Membrane Transport Proteins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Membrane Transport Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Membrane Transport Proteins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.