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Author: 3Island Press
Publisher:
ISBN: 9781461321408
Category :
Languages : en
Pages : 436
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Book Description
Author: 3Island Press
Publisher:
ISBN: 9781461321408
Category :
Languages : en
Pages : 436
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Book Description
Author: Luigi F. Agnati
Publisher: Springer Science & Business Media
ISBN: 1461321395
Category : Medical
Languages : en
Pages : 416
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Book Description
Author: Luigi F. Agnati
Publisher:
ISBN: 9780333396377
Category : Neural transmission
Languages : en
Pages : 418
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Book Description
Author: Luigi Francesco Agnati
Publisher:
ISBN:
Category : Neuroanatomy
Languages : en
Pages : 0
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Book Description
Author: Julian M L Budd
Publisher: Frontiers Media SA
ISBN: 2889197964
Category : Computational neuroscience
Languages : en
Pages : 246
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Book Description
The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.
Author: Richard Wootton
Publisher: CUP Archive
ISBN: 9780521434829
Category : Medical
Languages : en
Pages : 466
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Book Description
This volume provides a timely and useful introduction to the theory and practical application of image analysis in histology. This powerful research technique can be used to detect not only stored products in a cell (immunocytochemistry) but the synthetic machinery and the genes that control it (in situ hybridisation), as well as the specific binding sites that act as receptors for a molecule following its release (in vitro autoradiography). The book provides a good introduction for beginners before looking in greater detail at more advanced material in selected areas. The volume highlights the importance of technique in gathering quantitative information. The book is divided into four sections: introductory material, image acquisition, image processing, and applications. The applications areas include quantitative immunochemistry, quantification of nerves and neurotransmitters and automated grain counting in in situ hybridisation histochemistry.
Author: Detlev Ganten
Publisher: Springer Science & Business Media
ISBN: 3642727387
Category : Medical
Languages : en
Pages : 335
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Book Description
With contributions by numerous experts
Author: P.J. Roberts
Publisher: Springer
ISBN: 1349084794
Category : Medical
Languages : en
Pages : 513
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Book Description
Author: Stephen M Evans
Publisher: Oxford University Press
ISBN: 0191500097
Category : Medical
Languages : en
Pages :
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Book Description
Stereology is a valuable tool for neuroscientists, allowing them to obtain 3-Dimensional information from 2-Dimensional measurements made on appropriately sampled sections (usually obtained from histological sections or MRI/CT/PET scans). This 3-D information is invaluable in correlating structural/functional relationships in the pursuit of far greater understanding of the function of the central nervous system. However, in carrying out such measurements, often based on limited data sets, there is a risk of experimenter bias. An important feature of modern design based stereology is to be aware of potential sources of bias and eliminate them during the data collection. With many of the major neuroscience journals now insisting that quantitative data be presented, there is a greater need than ever for neuroscientists to understand the theory and practice behind quantitative methods, such as those offered by stereology. Quantitative Methods in Neuroscience is a cookbook of stereological methods written especially for neuroscientists. It provides clear and accessible advice about when and when not to use stereology. Throughout the book, the emphasis is on practical guidance, rather than discussions and formulae. Written by leading scientists in the field of stereology, with a Foreword by D.C. Sterio, the book will be a valuable introduction to these methods for neuroscientists, and all those involved in development of new drug programmes.
Author: Kjell Fuxe
Publisher: Springer
ISBN: 1349089494
Category : Science
Languages : en
Pages : 577
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Book Description
