Protein Electrophoresis in Clinical Diagnosis

Protein Electrophoresis in Clinical Diagnosis PDF Author: David Keren
Publisher: CRC Press
ISBN: 1444113992
Category : Medical
Languages : en
Pages : 415

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Book Description
Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques,

Protein Electrophoresis in Clinical Diagnosis

Protein Electrophoresis in Clinical Diagnosis PDF Author: David Keren
Publisher: CRC Press
ISBN: 0340812133
Category : Medical
Languages : en
Pages : 415

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Book Description
Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques, immunofixation techniques, approaches to pattern interpretation, and pattern interpretation in both cerebralspinal fluid and urine. Conditions associated with Monoclunal Gammopathies are considered, as are the appropriate strategies for their detection. David Keren is well-known as the leader in this field, his work on guidelines becoming the benchmark for all those involved in protein detection in serum and urine. Dr Keren's book will be essential in every laboratory, and read by pathologists, chemical chemists, medical technicians and clinicians (particularly hematologists and oncologists).

Protein Electrophoresis in Clinical Diagnosis

Protein Electrophoresis in Clinical Diagnosis PDF Author: David F. Keren
Publisher: American Society of Clinical Pathologists Press
ISBN: 9780891895916
Category : Medical
Languages : en
Pages : 256

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Book Description
With the publication of Protein Electrophoresis in Clinical Diagnosis, Dr. Keren brings us up to date on the considerable advances that have been made in the field. Dr. Keren presents the most clinically useful major advances in our knowledge of -- and ability to detect -- protein abnormalities by electrophoresis and immunoassay. This book goes the "extra mile" beyond reporting on advances by: * reviewing issues that are encountered with the use of capillary electrophorssis * providing examples of how gel-based methods are being used to detect M-proteins * illustrating characterization of M-proteins by immunofixation and immunosubtraction * sharing strategies for efficient use of new techniques * presenting a wealth of cases that demonstrate challenging and classic examples of the various methods discussed in the book 272 Pages; 64 Tables; 309 Figures; 47 Interpretive case studies

Clinical Applications of Capillary Electrophoresis

Clinical Applications of Capillary Electrophoresis PDF Author: Stephen M. Palfrey
Publisher: Springer Science & Business Media
ISBN: 1592596894
Category : Medical
Languages : en
Pages : 215

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Book Description
In Clinical Applications of Capillary Electrophoresis, Stephen Palfrey brings together for first time a collection of detailed capillary electrophoresis protocols designed exclusively for clinical applications. Written by the leading scientists who have often perfected these methods in their own laboratories, the protocols furnish new and more powerful assays for many routine serum and blood tests now regularly performed in clinical laboratories, including urine protein analysis, hemoglobin separation, and the detection of CSF proteins, lipoproteins, myoglobin, cryoglobulins, HbA1c, and cathepsin. The protocols offered for DNA studies include double-stranded DNA analysis, the prenatal diagnosis of Down's syndrome, Rh D/d genotyping, the identification of mutated p53 oncogene, and the detection of microsatellite instability in cancers. Many of the methods can be automated to replace the more costly and labor-intensive tests that are currently used in most clinical laboratories. Clinical Applications of Capillary Electrophoresis demonstrates clearly the simplicity, versatility, and power of CE over conventional methods. It offers to beginning clinical investigators, as well as established laboratories new to the technique, a representative range of highly practical CE methods-assays that are not only certain to become ever more productive, but are already eminently useful today.

Multiple Myeloma and Related Serum Protein Disorders

Multiple Myeloma and Related Serum Protein Disorders PDF Author: Neil S. Harris, MD
Publisher: Demos Medical Publishing
ISBN: 1933864753
Category : Medical
Languages : en
Pages : 163

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Book Description
A practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens.

Laboratory Screening and Diagnostic Evaluation

Laboratory Screening and Diagnostic Evaluation PDF Author: Kelly Small Casler, DNP, APRN, FNP-BC, CHSE
Publisher: Springer Publishing Company
ISBN: 0826140939
Category : Medical
Languages : en
Pages : 1111

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Book Description
"[the authors] did a masterful job of creating and editing this gold standard book that should be used by all clinicians and incorporated into all nursing and health sciences curriculums." -Bernadette Mazurek Melnyk, PhD, APRN-CNP, FNAP, FAANP, FAAN Vice President for Health Promotion University Chief Wellness Officer Dean and Helene Fuld Health Trust Professor of Evidence-Based Practice, College of Nursing Professor of Pediatrics & Psychiatry, College of Medicine Executive Director, the Helene Fuld Health Trust National Institute for EBP The Ohio State University This is the only book to explicitly guide clinicians through an evidence-based approach to ordering and interpreting laboratory tests. With over 160 commonly ordered tests, this book is designed to foster more accurate clinical decision-making to attain the highest level of patient care. This book summarizes more than 3000 pieces of evidence and incorporates clinical expertise and decision-making on the ordering and interpretation of tests. To promote ease of use, a convenient table maps labs and their corresponding chapter numbers to the relevant body system to promote ease of use. Each laboratory test is presented in a consistent format with information on physiology, indications (screening, diagnosis, and monitoring), algorithms, test interpretation and follow-up testing, patient education, and related diagnoses. Additional valuable features include clinical pearls that highlight common pitfalls and gaps in reasoning, and a cost-benefit analysis. This book also includes CPT and ICD-10 codes, charts and tables for clarification, and references for further study. Key Features: Delivers a strong, evidence-based approach to ordering and interpreting over 160 laboratory tests Promotes accurate clinical decision-making toward achieving the Triple Aim Includes abundant clinical pearls highlighting common pitfalls and gaps in reasoning Provides cost-benefit analysis and discussion of laboratory testing within a high-value healthcare culture Includes 175 supplemental case examples and 200 self-assessment questions to facilitate instruction and learning Includes more than 3000 pieces of evidence from interprofessional resources

Serum Free Light Chain Analysis

Serum Free Light Chain Analysis PDF Author: A. R. Bradwell
Publisher:
ISBN: 9780704425293
Category : Medical
Languages : en
Pages : 310

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Book Description


Multiple Myeloma

Multiple Myeloma PDF Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1461485207
Category : Medical
Languages : en
Pages : 311

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Book Description
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Electrophoresis & Immunofixation

Electrophoresis & Immunofixation PDF Author: Najat Rashid
Publisher: Jaypee Brothers,Medical Publishers Pvt. Limited
ISBN: 9789350904299
Category : Medical
Languages : en
Pages : 302

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Book Description
Immunofixation electrophoresis is the process of separating proteins in the blood (serum) or urine using an electric current to move them across a thin layer of gel. It is used to identify the presence or absence of abnormal proteins and to detect, diagnose and monitor the course and treatment of conditions associated with these proteins, including multiple myeloma and other related diseases. (Lab Test Online UK). This manual guides practitioners through the technique and interpretation of immunofixation electrophoresis. Beginning with an introduction, the book provides a step by step description of the techniques, instruments, electrophoresis patterns and their interpretation, stains used, and diseases that may be diagnosed with this process. More than 200 full colour images and illustrations enhance learning. Key points Step by step guide to immunofixation electrophoresis Describes different methods and their interpretation Covers diseases that may be diagnosed using electrophoresis, including multiple myeloma Includes more than 200 full colour images and illustrations

Thoracic Image Analysis

Thoracic Image Analysis PDF Author: Jens Petersen
Publisher: Springer
ISBN: 9783030624682
Category : Computers
Languages : en
Pages : 166

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Book Description
This book constitutes the proceedings of the Second International Workshop on Thoracic Image Analysis, TIA 2020, held in Lima, Peru, in October 2020. Due to COVID-19 pandemic the conference was held virtually. COVID-19 infection has brought a lot of attention to lung imaging and the role of CT imaging in the diagnostic workflow of COVID-19 suspects is an important topic. The 14 full papers presented deal with all aspects of image analysis of thoracic data, including: image acquisition and reconstruction, segmentation, registration, quantification, visualization, validation, population-based modeling, biophysical modeling (computational anatomy), deep learning, image analysis in small animals, outcome-based research and novel infectious disease applications.