Propriospinal Neurons: Essential Elements in Locomotion, Autonomic Function and Plasticity after Spinal Cord Injury and Disease PDF Download
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Author: Katinka Stecina
Publisher: Frontiers Media SA
ISBN: 2889669165
Category : Science
Languages : en
Pages : 177
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Book Description
Author: Katinka Stecina
Publisher: Frontiers Media SA
ISBN: 2889669165
Category : Science
Languages : en
Pages : 177
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Book Description
Author: Shuxin Li
Publisher: Frontiers Media SA
ISBN: 288974633X
Category : Science
Languages : en
Pages : 399
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Book Description
Author: Susan J. Harkema
Publisher:
ISBN: 0195342089
Category : Medical
Languages : en
Pages : 200
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Book Description
Physical rehabilitation for walking recovery after spinal cord injury is undergoing a paradigm shift. Therapy historically has focused on compensation for sensorimotor deficits after SCI using wheelchairs and bracing to achieve mobility. With locomotor training, the aim is to promote recovery via activation of the neuromuscular system below the level of the lesion. What basic scientists have shown us as the potential of the nervous system for plasticity, to learn, even after injury is being translated into a rehabilitation strategy by taking advantage of the intrinsic biology of the central nervous system. While spinal cord injury from basic and clinical perspectives was the gateway for developing locomotor training, its application has been extended to other populations with neurologic dysfunction resulting in loss of walking or walking disability.
Author: Charles Watson
Publisher: Academic Press
ISBN: 0080921388
Category : Medical
Languages : en
Pages : 408
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Book Description
Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN). - The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements - The major topics addressed are: development of the spinal cord; the gross anatomy of the spinal cord and its meninges; spinal nerves, nerve roots, and dorsal root ganglia; the vertebral column, vertebral joints, and vertebral muscles; blood supply of the spinal cord; cytoarchitecture and chemoarchitecture of the spinal gray matter; musculotopic anatomy of motoneuron groups; tracts connecting the brain and spinal cord; spinospinal pathways; sympathetic and parasympathetic elements in the spinal cord; neuronal groups and pathways that control micturition; the anatomy of spinal cord injury in experimental animals - The atlas of the rat and mouse spinal cord has the following features: Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse; Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level. ; Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN) - All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply
Author: Giuseppe Perale
Publisher: Woodhead Publishing
ISBN: 0081028083
Category : Technology & Engineering
Languages : en
Pages : 348
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Book Description
Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. - Covers current and future repair strategies for spinal cord injury repair - Focuses on key research trends, clinics, biology and engineering - Provides fundamentals on regenerative engineering and tissue engineering
Author: Eric Stalberg
Publisher: Springer Science & Business Media
ISBN: 3709164648
Category : Medical
Languages : en
Pages : 520
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Book Description
During the last decades, research on spinal cord has attracted a great deal of attention because of problems such as sensory-motor and autonomic dysfunctions associated with traumatic and other injuries. Recording of spinal cord evoked potentials is one of the most promising approaches to understand the spinal cord function. However, the details of the evoked potentials and their significance in various pathological conditions are not yet fully characterized. This book summarizes new findings in the field of electrophysiology and relates this knowledge to pathology and regeneration research. It is the first one which deals in great detail with various ways to monitor spinal cord function in experimental and clinical situations. It provides an up-to-date knowledge regarding spinal cord bioelectrical activity and its modification with pharmacological agents and covers new aspects of regeneration studies, particularly the role of myelin associated inhibitory molecules. A section is devoted to clinical studies dealing with electrical activity, pathology, and current therapeutic measures. This volume will be useful both to basic and clinical neuroscientists engaged in the field of neurology, neurophysiology, neurochemistry, neurosurgery, neuropathology, and related disciplines in order to understand basic functions of the spinal cord and to stimulate further research in this rapidly advancing field.
Author: Milan R. Dimitrijevic
Publisher: OUP USA
ISBN: 0199746508
Category : Medical
Languages : en
Pages : 337
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Book Description
Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach. Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.
Author: Hongyun Huang
Publisher: Nova Science Publishers
ISBN: 9781634636001
Category : Nervous system
Languages : en
Pages : 0
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Book Description
Neurorestoratology is one of the most important disciplines in modern medicine and is also the most important discipline in neuroscience. Its core aim is to restore, promote and maintain the integrity of impaired or lost neuronal functions and/or structures by using novel cell-based comprehensive neurorestorative strategies. This book is the first and a unique one that systematically expounds the main aspects of neurorestoratology, which includes three sections with 22 chapters in two volumes. It systematically elaborates CNS neurorestorable theory and neurorestorative mechanisms. It firstly comprehends the Neurorestorative Process as a whole and Neurorestorative law. It fully describes all neurorestorative strategies and their continuing clinical progresses and achievements, especially the cell-based comprehensive neurorestorative strategies.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1104
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Book Description
Author: Randy W. Beck
Publisher: Elsevier Health Sciences
ISBN: 0702051047
Category : Medical
Languages : en
Pages : 414
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Book Description
Functional Neurology utilizes our understanding of how the nervous system works in the treatment of a variety of clinical conditions. Fuctional Neurology for Practitioners of Manual Medicine takes the reader from the embryonic beginnings of the nervous system, through the biochemistry of receptor activation and on to the functional systems of the nervous system. Both the student and the clinician will find this text a valuable source of information and clinical guidance in the application of detailed neurological principles to their practice. Concepts, relationships and scientific mechanisms of the nervous system function are covered, and this aids the practitioner in developing their clinical approach to a wide variety of patient presentations. This text explores the neurological impact of the application of functional neurological principles, using a detailed clinical approach supported by clinical case studies. The text is fully referenced, which allows the reader to immediately apply the concepts to practice situations. New for this edition are new chapters on pain (including headache) and theoretical evidence, plus extensive electronic resources supporting the text. - Utilizes our understanding of how the nervous system works in the treatment of a variety of clinical conditions - Demystifies the clinical results seen in the practice of Functional Neurology and scientifically validates its clinical success - Addresses function rather than pathology, allowing the reader to gain a firm understanding of the neurological processes seen in health and disease - Contains clinical cases which are designed to be read and answered before starting the chapter to allow the reader to gauge their current state of knowledge - 'Quick Facts' introduce new concepts or allow rapid review of information already presented in the text in a brief and succinct manner - Contains a detailed overview of the concepts relating to our understanding of the development of emotion to demonstrate the link between physical health and the mind - Contains abundant references to support controversial concepts - Contains new chapters on theoretical evidence and the management of pain (including headache) - Contains a wide range of additional case studies, 'clinical conundrums' and key questions and answers for each topic - Bonus DVD contains fully searchable text, a downloadable image bank, brain dissection and video clips of the manipulative techniques and examination procedures found within the volume plus 200 multiple choice questions
