Probing the Mechanism of Maltose Transport in Escherichia Coli PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Probing the Mechanism of Maltose Transport in Escherichia Coli PDF full book. Access full book title Probing the Mechanism of Maltose Transport in Escherichia Coli by Gonzalo Merino. Download full books in PDF and EPUB format.
Author: Gonzalo Merino
Publisher:
ISBN:
Category :
Languages : en
Pages : 358
Get Book Here
Book Description
Author: Gonzalo Merino
Publisher:
ISBN:
Category :
Languages : en
Pages : 358
Get Book Here
Book Description
Author: David Andrew Dean
Publisher:
ISBN:
Category :
Languages : en
Pages : 516
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 806
Get Book Here
Book Description
Author: Anthony M. George
Publisher: Springer
ISBN: 3319234765
Category : Science
Languages : en
Pages : 384
Get Book Here
Book Description
This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer’s disease, this ABC transporter still eludes a clinical solution to its multidrug resistance property. ABC transporters are integral membrane active proteins and they belong to one of the largest protein families across all species. Their myriad roles encompass the import or export of a diverse range of allocrites, including ion, nutrients, peptides, polysaccharides, lipids, and xenobiotics. They are of major medical importance with many members elaborating multidrug resistance in bacteria, fungi, yeast, parasites, and humans. Other ABC transporters are involved in a number of inherited diseases, including cystic fibrosis, macular degeneration, gout, and several other metabolic disorders
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 854
Get Book Here
Book Description
Author: Xian-Zhi Li
Publisher: Springer
ISBN: 3319396587
Category : Medical
Languages : en
Pages : 850
Get Book Here
Book Description
This book, written by leading international experts, provides a comprehensive, current examination of transport-mediated antimicrobial resistance. As a particularly powerful mechanism of multidrug resistance, an in-depth examination of efflux pumps is conducted with bacteria of major public health concern including Enterobacteriaceae, Acinetobacter, Neisseria, Pseudomonas, staphylococci, and mycobacteria. The content spans structural biochemistry and transport mechanisms of the major transporter families and considers individual drug efflux systems across various Gram-positive and Gram-negative species. Genomic analysis of efflux pump distribution and their contribution to clinically-relevant resistance are a major focus of the text. Moreover, interplay between drug efflux pumps and other key resistance mechanisms such as intrinsic drug impermeability, inactivation, and target alterations are discussed, as well as their molecular expression-based regulation and physiological functions beyond resistance, involving biofilms, stress response, and pathogenicity. Finally, strategies are addressed to target this drug resistance mechanism with novel antimicrobials or drug inhibitor adjuvants.
Author: Markus Geisler
Publisher: Springer
ISBN: 3319065114
Category : Science
Languages : en
Pages : 333
Get Book Here
Book Description
This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species. ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids. The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470514159
Category : Science
Languages : en
Pages : 282
Get Book Here
Book Description
How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallography, protein engineering and molecular modeling offer provocative insights into current views on the protein folding problem and various aspects for future progress.
Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 2626
Get Book Here
Book Description
Author: I Barry Holland
Publisher: Elsevier
ISBN: 0080481876
Category : Medical
Languages : en
Pages : 672
Get Book Here
Book Description
ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. - Phylogeny and Evoloution of ABC Transporters - Fundamental Aspects of the Mechanism of Action of ABC Transporters - Prokaryote ABC Transporters - Non-Mammalian Transporters - Multidrug Transporters - ABC Transporters, Physiological Roles and Human Disease - Full color throughout
