Probabilistic Models of the Brain

Probabilistic Models of the Brain PDF Author: Rajesh P.N. Rao
Publisher: MIT Press
ISBN: 9780262264327
Category : Medical
Languages : en
Pages : 348

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Book Description
A survey of probabilistic approaches to modeling and understanding brain function. Neurophysiological, neuroanatomical, and brain imaging studies have helped to shed light on how the brain transforms raw sensory information into a form that is useful for goal-directed behavior. A fundamental question that is seldom addressed by these studies, however, is why the brain uses the types of representations it does and what evolutionary advantage, if any, these representations confer. It is difficult to address such questions directly via animal experiments. A promising alternative is to use probabilistic principles such as maximum likelihood and Bayesian inference to derive models of brain function. This book surveys some of the current probabilistic approaches to modeling and understanding brain function. Although most of the examples focus on vision, many of the models and techniques are applicable to other modalities as well. The book presents top-down computational models as well as bottom-up neurally motivated models of brain function. The topics covered include Bayesian and information-theoretic models of perception, probabilistic theories of neural coding and spike timing, computational models of lateral and cortico-cortical feedback connections, and the development of receptive field properties from natural signals.

Probabilistic Models of the Brain

Probabilistic Models of the Brain PDF Author: Rajesh P.N. Rao
Publisher: MIT Press
ISBN: 9780262264327
Category : Medical
Languages : en
Pages : 348

Get Book

Book Description
A survey of probabilistic approaches to modeling and understanding brain function. Neurophysiological, neuroanatomical, and brain imaging studies have helped to shed light on how the brain transforms raw sensory information into a form that is useful for goal-directed behavior. A fundamental question that is seldom addressed by these studies, however, is why the brain uses the types of representations it does and what evolutionary advantage, if any, these representations confer. It is difficult to address such questions directly via animal experiments. A promising alternative is to use probabilistic principles such as maximum likelihood and Bayesian inference to derive models of brain function. This book surveys some of the current probabilistic approaches to modeling and understanding brain function. Although most of the examples focus on vision, many of the models and techniques are applicable to other modalities as well. The book presents top-down computational models as well as bottom-up neurally motivated models of brain function. The topics covered include Bayesian and information-theoretic models of perception, probabilistic theories of neural coding and spike timing, computational models of lateral and cortico-cortical feedback connections, and the development of receptive field properties from natural signals.

Bayesian Brain

Bayesian Brain PDF Author: Kenji Doya
Publisher: MIT Press
ISBN: 026204238X
Category : Bayesian statistical decision theory
Languages : en
Pages : 341

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Book Description
Experimental and theoretical neuroscientists use Bayesian approaches to analyze the brain mechanisms of perception, decision-making, and motor control.

Computational Models of Brain and Behavior

Computational Models of Brain and Behavior PDF Author: Ahmed A. Moustafa
Publisher: John Wiley & Sons
ISBN: 1119159067
Category : Psychology
Languages : en
Pages : 586

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Book Description
A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Goal-Directed Decision Making

Goal-Directed Decision Making PDF Author: Richard W. Morris
Publisher: Academic Press
ISBN: 0128120991
Category : Science
Languages : en
Pages : 484

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Book Description
Goal-Directed Decision Making: Computations and Neural Circuits examines the role of goal-directed choice. It begins with an examination of the computations performed by associated circuits, but then moves on to in-depth examinations on how goal-directed learning interacts with other forms of choice and response selection. This is the only book that embraces the multidisciplinary nature of this area of decision-making, integrating our knowledge of goal-directed decision-making from basic, computational, clinical, and ethology research into a single resource that is invaluable for neuroscientists, psychologists and computer scientists alike. The book presents discussions on the broader field of decision-making and how it has expanded to incorporate ideas related to flexible behaviors, such as cognitive control, economic choice, and Bayesian inference, as well as the influences that motivation, context and cues have on behavior and decision-making. Details the neural circuits functionally involved in goal-directed decision-making and the computations these circuits perform Discusses changes in goal-directed decision-making spurred by development and disorders, and within real-world applications, including social contexts and addiction Synthesizes neuroscience, psychology and computer science research to offer a unique perspective on the central and emerging issues in goal-directed decision-making

Graphical Models

Graphical Models PDF Author: Michael Irwin Jordan
Publisher: MIT Press
ISBN: 9780262600422
Category : Artificial intelligence
Languages : en
Pages : 450

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Book Description
This book exemplifies the interplay between the general formal framework of graphical models and the exploration of new algorithm and architectures. The selections range from foundational papers of historical importance to results at the cutting edge of research. Graphical models use graphs to represent and manipulate joint probability distributions. They have their roots in artificial intelligence, statistics, and neural networks. The clean mathematical formalism of the graphical models framework makes it possible to understand a wide variety of network-based approaches to computation, and in particular to understand many neural network algorithms and architectures as instances of a broader probabilistic methodology. It also makes it possible to identify novel features of neural network algorithms and architectures and to extend them to more general graphical models.This book exemplifies the interplay between the general formal framework of graphical models and the exploration of new algorithms and architectures. The selections range from foundational papers of historical importance to results at the cutting edge of research. Contributors H. Attias, C. M. Bishop, B. J. Frey, Z. Ghahramani, D. Heckerman, G. E. Hinton, R. Hofmann, R. A. Jacobs, Michael I. Jordan, H. J. Kappen, A. Krogh, R. Neal, S. K. Riis, F. B. Rodríguez, L. K. Saul, Terrence J. Sejnowski, P. Smyth, M. E. Tipping, V. Tresp, Y. Weiss

Decisions, Uncertainty, and the Brain

Decisions, Uncertainty, and the Brain PDF Author: Paul W. Glimcher
Publisher: MIT Press
ISBN: 9780262572279
Category : Medical
Languages : en
Pages : 404

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Book Description
In this provocative book, Paul Glimcher argues that economic theory may provide an alternative to the classical Cartesian model of the brain and behavior. Glimcher argues that Cartesian dualism operates from the false premise that the reflex is able to describe behavior in the real world that animals inhabit. A mathematically rich cognitive theory, he claims, could solve the most difficult problems that any environment could present, eliminating the need for dualism by eliminating the need for a reflex theory. Such a mathematically rigorous description of the neural processes that connect sensation and action, he explains, will have its roots in microeconomic theory. Economic theory allows physiologists to define both the optimal course of action that an animal might select and a mathematical route by which that optimal solution can be derived. Glimcher outlines what an economics-based cognitive model might look like and how one would begin to test it empirically. Along the way, he presents a fascinating history of neuroscience. He also discusses related questions about determinism, free will, and the stochastic nature of complex behavior.

Magnetic Resonance Scanning and Epilepsy

Magnetic Resonance Scanning and Epilepsy PDF Author: Simon D. Shorvon
Publisher: Springer Science & Business Media
ISBN: 1461525462
Category : Medical
Languages : en
Pages : 297

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Book Description
It was only in 1980 that the first recognisable magnetic resonance images of the human brain were published, by Moore and Holland from Nottingham University in England. There then followed a number of clinical trials of brain imaging, the most notable from the Hammersmith Hospital in London using a system designed by EMI, the original manufacturers of the first CT machines. A true revolution in medicine has ensued; in only a few years there are thousands of scanning units, and magnetic resonance imaging (MRI) has assumed a central importance in medical investigation. It is an extraordinary fact that within a few years of development, the esoteric physics of nuclear spin, angular momentum, and magnetic vector precession were harnessed to provide exquisite images of living anatomy; modem science has no greater tribute. That indisputable king of neurology and the oldest of recorded conditions, epilepsy, has not been untouched by the new technology; indeed, it is our view that the introduction of MRI of electroencephalography (EEG) in the late has been as important to epilepsy as was that 1930s. Now, for the first time, the structural and aetiological basis of the condition is susceptible to thorough investigation, and MRI can provide structural detail to parallel the functional detail of EEG. MRI has the same potential as had EEG over 50 years ago, to provide a new level of understanding of the basic mechanisms, the clinical features and the treatment of epilepsy.

Probabilistic Perspectives on Brain (dys)Function

Probabilistic Perspectives on Brain (dys)Function PDF Author: Karl Friston
Publisher: Frontiers Media SA
ISBN: 2889711285
Category : Science
Languages : en
Pages : 172

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Book Description


Data-Driven Computational Neuroscience

Data-Driven Computational Neuroscience PDF Author: Concha Bielza
Publisher: Cambridge University Press
ISBN: 110849370X
Category : Computers
Languages : en
Pages : 709

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Book Description
Trains researchers and graduate students in state-of-the-art statistical and machine learning methods to build models with real-world data.

Information Processing in Medical Imaging

Information Processing in Medical Imaging PDF Author: Chris Taylor
Publisher: Springer Science & Business Media
ISBN: 3540405607
Category : Computers
Languages : en
Pages : 714

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Book Description
This book constitutes the refeered proceedings of the 18th Interational Conference on Information Processing in Medical Imaging, IPMI 2003, held in UK, in July 2003. The 57 revised full papers presented were carefully reviewed and selected from submissions. The papers are organized in topical sections shape modeling, shape analysis, segmentation, color, performance characterization, registration and modeling similarity, registration and modeling deformation, cardiac motion, fMRI analysis, and diffusion imaging and tractography.