Author: Murray R. Selwyn
Publisher: CRC Press
ISBN: 9780849394614
Category : Science
Languages : en
Pages : 176
Book Description
Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!
Principles of Experimental Design for the Life Sciences
Author: Murray R. Selwyn
Publisher: CRC Press
ISBN: 9780849394614
Category : Science
Languages : en
Pages : 176
Book Description
Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!
Publisher: CRC Press
ISBN: 9780849394614
Category : Science
Languages : en
Pages : 176
Book Description
Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!
Experimental Design for the Life Sciences
Author: Graeme D. Ruxton
Publisher:
ISBN: 9780191975202
Category : Experimental design
Languages : en
Pages : 0
Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Publisher:
ISBN: 9780191975202
Category : Experimental design
Languages : en
Pages : 0
Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
The Design of Experiments in Neuroscience
Author: Mary E. Harrington
Publisher: Cambridge University Press
ISBN: 1108656331
Category : Psychology
Languages : en
Pages : 201
Book Description
Using engaging prose, Mary E. Harrington introduces neuroscience students to the principles of scientific research including selecting a topic, designing an experiment, analyzing data, and presenting research. This new third edition updates and clarifies the book's wealth of examples while maintaining the clear and effective practical advice of the previous editions. New and expanded topics in this edition include techniques such as optogenetics and conditional transgenes as well as a discussion of rigor and reproducibility in neuroscience research. Extended coverage of descriptive and inferential statistics arms readers with the analytical tools needed to interpret data. Throughout, practical guidelines are provided on avoiding experimental design problems, presenting research including creating posters and giving talks, and using a '12-step guide' to reading scientific journal articles.
Publisher: Cambridge University Press
ISBN: 1108656331
Category : Psychology
Languages : en
Pages : 201
Book Description
Using engaging prose, Mary E. Harrington introduces neuroscience students to the principles of scientific research including selecting a topic, designing an experiment, analyzing data, and presenting research. This new third edition updates and clarifies the book's wealth of examples while maintaining the clear and effective practical advice of the previous editions. New and expanded topics in this edition include techniques such as optogenetics and conditional transgenes as well as a discussion of rigor and reproducibility in neuroscience research. Extended coverage of descriptive and inferential statistics arms readers with the analytical tools needed to interpret data. Throughout, practical guidelines are provided on avoiding experimental design problems, presenting research including creating posters and giving talks, and using a '12-step guide' to reading scientific journal articles.
Design of Experiments for Agriculture and the Natural Sciences
Author: Reza Hoshmand
Publisher: CRC Press
ISBN: 1420010646
Category : Technology & Engineering
Languages : en
Pages : 452
Book Description
Written to meet the needs of both students and applied researchers, Design of Experiments for Agriculture and the Natural Sciences, Second Edition serves as an introductory guide to experimental design and analysis. Like the popular original, this thorough text provides an understanding of the logical underpinnings of design and analysis by selecting and discussing only those carefully chosen designs that offer the greatest utility. However, it improves on the first edition by adhering to a step-by-step process that greatly improves accessibility and understanding. Real problems from different areas of agriculture and science are presented throughout to show how practical issues of design and analysis are best handled. Completely revised to greatly enhance readability, this new edition includes: A new chapter on covariance analysis to help readers reduce errors, while enhancing their ability to examine covariances among selected variables Expanded material on multiple regression and variance analysis Additional examples, problems, and case studies A step-by-step MinitabĀ® guide to help with data analysis Intended for those in the agriculture, environmental, and natural science fields as well as statisticians, this text requires no previous exposure to analysis of variance, although some familiarity with basic statistical fundamentals is assumed. In keeping with the book's practical orientation, numerous workable problems are presented throughout to reinforce the reader's ability to creatively apply the principles and concepts in any given situation.
Publisher: CRC Press
ISBN: 1420010646
Category : Technology & Engineering
Languages : en
Pages : 452
Book Description
Written to meet the needs of both students and applied researchers, Design of Experiments for Agriculture and the Natural Sciences, Second Edition serves as an introductory guide to experimental design and analysis. Like the popular original, this thorough text provides an understanding of the logical underpinnings of design and analysis by selecting and discussing only those carefully chosen designs that offer the greatest utility. However, it improves on the first edition by adhering to a step-by-step process that greatly improves accessibility and understanding. Real problems from different areas of agriculture and science are presented throughout to show how practical issues of design and analysis are best handled. Completely revised to greatly enhance readability, this new edition includes: A new chapter on covariance analysis to help readers reduce errors, while enhancing their ability to examine covariances among selected variables Expanded material on multiple regression and variance analysis Additional examples, problems, and case studies A step-by-step MinitabĀ® guide to help with data analysis Intended for those in the agriculture, environmental, and natural science fields as well as statisticians, this text requires no previous exposure to analysis of variance, although some familiarity with basic statistical fundamentals is assumed. In keeping with the book's practical orientation, numerous workable problems are presented throughout to reinforce the reader's ability to creatively apply the principles and concepts in any given situation.
Experimental Design for Laboratory Biologists
Author: Stanley E. Lazic
Publisher: Cambridge University Press
ISBN: 1316810674
Category : Medical
Languages : en
Pages : 429
Book Description
Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.
Publisher: Cambridge University Press
ISBN: 1316810674
Category : Medical
Languages : en
Pages : 429
Book Description
Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.
Experimental Design for the Life Sciences
Author: Graeme Ruxton
Publisher: Oxford University Press, USA
ISBN: 0199569126
Category : Education
Languages : en
Pages : 197
Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Publisher: Oxford University Press, USA
ISBN: 0199569126
Category : Education
Languages : en
Pages : 197
Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Understanding Statistics and Experimental Design
Author: Michael H. Herzog
Publisher: Springer
ISBN: 3030034992
Category : Science
Languages : en
Pages : 146
Book Description
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.
Publisher: Springer
ISBN: 3030034992
Category : Science
Languages : en
Pages : 146
Book Description
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.
Practical Statistics and Experimental Design for Plant and Crop Science
Author: Alan G. Clewer
Publisher: John Wiley & Sons
ISBN: 1118685660
Category : Science
Languages : en
Pages : 315
Book Description
Presents readers with a user-friendly, non-technical introductionto statistics and the principles of plant and crop experimentation.Avoiding mathematical jargon, it explains how to plan and design anexperiment, analyse results, interpret computer output and presentfindings. Using specific crop and plant case studies, this guidepresents: * The reasoning behind each statistical method is explained beforegiving relevant, practical examples * Step-by-step calculations with examples linked to three computerpackages (MINITAB, GENSTAT and SAS) * Exercises at the end of many chapters * Advice on presenting results and report writing Written by experienced lecturers, this text will be invaluable toundergraduate and postgraduate students studying plant sciences,including plant and crop physiology, biotechnology, plant pathologyand agronomy, plus ecology and environmental science students andthose wanting a refresher or reference book in statistics.
Publisher: John Wiley & Sons
ISBN: 1118685660
Category : Science
Languages : en
Pages : 315
Book Description
Presents readers with a user-friendly, non-technical introductionto statistics and the principles of plant and crop experimentation.Avoiding mathematical jargon, it explains how to plan and design anexperiment, analyse results, interpret computer output and presentfindings. Using specific crop and plant case studies, this guidepresents: * The reasoning behind each statistical method is explained beforegiving relevant, practical examples * Step-by-step calculations with examples linked to three computerpackages (MINITAB, GENSTAT and SAS) * Exercises at the end of many chapters * Advice on presenting results and report writing Written by experienced lecturers, this text will be invaluable toundergraduate and postgraduate students studying plant sciences,including plant and crop physiology, biotechnology, plant pathologyand agronomy, plus ecology and environmental science students andthose wanting a refresher or reference book in statistics.
Reproducibility and Replicability in Science
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486165
Category : Science
Languages : en
Pages : 257
Book Description
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.
Publisher: National Academies Press
ISBN: 0309486165
Category : Science
Languages : en
Pages : 257
Book Description
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.
Encyclopedia of Research Design
Author: Neil J. Salkind
Publisher: SAGE
ISBN: 1412961270
Category : Philosophy
Languages : en
Pages : 1779
Book Description
"Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.
Publisher: SAGE
ISBN: 1412961270
Category : Philosophy
Languages : en
Pages : 1779
Book Description
"Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.