Principles and Processes for Evaluating Endocrine Disruption in Wildlife

Principles and Processes for Evaluating Endocrine Disruption in Wildlife PDF Author: Ronald J. Kendall
Publisher: Setac Press
ISBN:
Category : Science
Languages : en
Pages : 528

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Principles and Processes for Evaluating Endocrine Disruption in Wildlife

Principles and Processes for Evaluating Endocrine Disruption in Wildlife PDF Author: Ronald J. Kendall
Publisher: Setac Press
ISBN:
Category : Science
Languages : en
Pages : 528

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Environmental Toxicology and Risk Assessment

Environmental Toxicology and Risk Assessment PDF Author: Diane Susan Henshel
Publisher: ASTM International
ISBN: 0803126182
Category : Biochemical markers
Languages : en
Pages : 500

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Physiology of the Cladocera

Physiology of the Cladocera PDF Author: Nikolai N. Smirnov
Publisher: Academic Press
ISBN: 0128052813
Category : Science
Languages : en
Pages : 420

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Book Description
Physiology of the Cladocera, Second Edition, is a much-needed summary of foundational information on these increasingly important model organisms. This unique and valuable review is based on the world's literature, including Russian research not previously widely available, and offers systematically arranged data on the physiology of Cladocera, assisting with explanation of their life and distribution. It features the addition of new sections and a vast amount of new information, such as the latest data on feeding, nutrition, pathological physiology, chemical composition, neurosecretion, and behavior, as well as hormonal regulation, antioxidants, and the biochemical background of effects of natural and anthropogenic factors. Additional expertly updated contributions in genetics and cytology, and a new chapter in embryology, round out the physiological chapters, and provide comprehensive insight into the state of knowledge of Cladocera and their underlying mechanisms. Cladocera crustaceans have become globally studied for many purposes, including genetic, molecular, ecological, environmental, water quality, systematics, and evolutionary biology research. Since the genome of Daphnia was sequenced and published, that system has gained much wider exposure, also leading to a rapidly growing awareness of the importance of understanding physiological processes as they relate to evolutionary and ecological genomics as well as ecogenomic toxicology. However, the physiological background on Cladocera has been fragmentary (including on the other 700 known species besides Daphnia), despite the extensive literature on species identification and morphology. This work addresses this issue by collecting and synthesizing from the literature the state of knowledge of cladoceran physiology, including discussion on both adequately and inadequately investigated fields, and thus directions of future research. - Summarizes fundamental information obtained in recent years, including on steroids, antioxidants, hormones, nanoparticles, and impact of wastewater of pharmaceutical industries - Provides the foundational information needed for scientists and practitioners from a variety of fields, including conservation and evolutionary biology, genomics, ecology, ecotoxicology, comparative physiology, limnology, zoology–carcinology, and water quality assessment - Features coverage of both Daphniids and representatives of other families, with attention drawn to little-studied aspects of their physiology, especially of those living in the litt oral zone - Includes guidance to the literature on cladoceran physiology in four languages - Discusses advantages and shortcomings of Cladocera as experimental animals and indicators of water quality

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264076247
Category :
Languages : en
Pages : 33

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Book Description
This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...

Endocrine Disruption and Human Health

Endocrine Disruption and Human Health PDF Author: Philippa D. Darbre
Publisher: Academic Press
ISBN: 0128011203
Category : Medical
Languages : en
Pages : 390

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Book Description
Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Endocrine Disruptors

Endocrine Disruptors PDF Author: M. Metzler
Publisher: Springer Science & Business Media
ISBN: 9783540422808
Category : Medical
Languages : en
Pages : 330

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Book Description
The field of endocrine disruption or endocrine active compounds (EACs), which is just emerging and still controversial, is comprehensively covered by leading experts in Volume 3, Subvolumes L (Part I) and M (the present volume, Part II). The major classes of endocrine active chemicals are discussed, as well as methods for their detection and their association with health disturbances in humans and wildlife. The etiology of several of the human diseases associated with endocrine disruptors, e.g. breast and prostate cancer, decreased fertility and malformations, is still poorly understood, and the current state of knowledge is presented. Since hormonally active agents appear to have the potential of both adverse and beneficial effects, the evidence of health benefits associated with endocrine active compounds in humans is also presented. Basic chapters on the mode of action of EACs and on the etiology of the associated diseases facilitate the understanding of this complex subject for non-medical readers.

Hormonally Active Agents in the Environment

Hormonally Active Agents in the Environment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309064198
Category : Science
Languages : en
Pages : 453

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Book Description
Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Endocrine Toxicology

Endocrine Toxicology PDF Author: J. Charles Eldridge
Publisher: CRC Press
ISBN: 142009310X
Category : Medical
Languages : en
Pages : 424

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Book Description
With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology's increased importance in environmental safety issues

Endocrine Disruption

Endocrine Disruption PDF Author: David O. Norris
Publisher: Oxford University Press
ISBN: 0195137493
Category : Medical
Languages : en
Pages : 492

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Book Description
Addresses the biological effects of the large number of compounds that have been recognized as endocrine disrupters. This book presents the relevant fundamentals of the endocrine systems of animals and humans, the toxicology, developmental toxicology, ecology, and risk assessment methods, and lays out the state of understanding for the field.

Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1576

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Book Description