Prescriptions hors autorisation de mise sur le marché en réanimation néonatale à l'Höpital Nord de Marseille PDF Download
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Author: Anne-Emmanuelle Fagour
Publisher:
ISBN:
Category :
Languages : fr
Pages : 242
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Book Description
Les progrès de la médecine actuelle impliquent aujourd'hui la prise en charge de prématurés de plus en plus précoces. Cependant les médicaments utilisés pour les traiter sont rarement évalués et adaptés. Les données de la littérature récente montrent que la prescription hors Autorisation de Mise sur le Marché (AMM)/ sans AMM est répandue en pédiatrie et que la population néonatale est la plus touchée par ce phénomène. L'objet de ce travail a été de réaliser une analyse descriptive de l'utilisation hors AMM/sans AMM des médicaments en réanimation néonatale à l'hôpital Nord de Marseille. Une étude prospective observationnelle de trois mois a été menée afin de quantifier la conformité des prescriptions de nouveau-nés admis en se référant au résumé des caractéristiques du produit (RCP). 107 nouveau-nés majoritairement prématurés, ont été inclus. Durant la période étudiée, 638 prescriptions ont été réalisées et analysées. Les traitements reçus étaient majoritairement hors AMM pour l'indication, puis pour la posologie et ensuite pour la catégorie d'âge. Les autres causes de prescriptions hors du cadre du RCP étaient le mode d'administration, la formulation et la voie d'administration. La plupart des nouveau-nés hospitalisés (94%), avait reçu au moins un traitement hors AMM. Cette étude montre que prescrire hors du cadre de l'AMM est un fait quotidien en réanimation néonatale. Les taux non négligeables des prescriptions hors AMM obtenus, essentiellement pour de smédicaments "hors brevets", soulignent le besoin de recherche clinique et d'approbation des données cliniques acquises validées au sein de la population néonatale.
Author: Anne-Emmanuelle Fagour
Publisher:
ISBN:
Category :
Languages : fr
Pages : 242
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Book Description
Les progrès de la médecine actuelle impliquent aujourd'hui la prise en charge de prématurés de plus en plus précoces. Cependant les médicaments utilisés pour les traiter sont rarement évalués et adaptés. Les données de la littérature récente montrent que la prescription hors Autorisation de Mise sur le Marché (AMM)/ sans AMM est répandue en pédiatrie et que la population néonatale est la plus touchée par ce phénomène. L'objet de ce travail a été de réaliser une analyse descriptive de l'utilisation hors AMM/sans AMM des médicaments en réanimation néonatale à l'hôpital Nord de Marseille. Une étude prospective observationnelle de trois mois a été menée afin de quantifier la conformité des prescriptions de nouveau-nés admis en se référant au résumé des caractéristiques du produit (RCP). 107 nouveau-nés majoritairement prématurés, ont été inclus. Durant la période étudiée, 638 prescriptions ont été réalisées et analysées. Les traitements reçus étaient majoritairement hors AMM pour l'indication, puis pour la posologie et ensuite pour la catégorie d'âge. Les autres causes de prescriptions hors du cadre du RCP étaient le mode d'administration, la formulation et la voie d'administration. La plupart des nouveau-nés hospitalisés (94%), avait reçu au moins un traitement hors AMM. Cette étude montre que prescrire hors du cadre de l'AMM est un fait quotidien en réanimation néonatale. Les taux non négligeables des prescriptions hors AMM obtenus, essentiellement pour de smédicaments "hors brevets", soulignent le besoin de recherche clinique et d'approbation des données cliniques acquises validées au sein de la population néonatale.
Author: Yasser Khazaal
Publisher: Frontiers Media SA
ISBN: 2889454967
Category : Video games in education
Languages : en
Pages : 311
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Book Description
Recent years have seen important developments in the computer and game industry, including the emergence of the concept of serious games. It is hypothesized that tools such as games, virtual reality, or applications for smartphones may foster learning, enhance motivation, promote behavioral change, support psychotherapy, favor empowerment, and improve some cognitive functions. Computers and games may create supports for training or help people with cognitive, emotional, or behavioral change. Games take various formats, from board games to informatics to games with interactive rules of play. Similarly, computer tools may vary widely in format, from self-help or assisted computerized training to virtual reality or applications for smartphones. Some tools that may be helpful for mental health were specifically designed for that goal, whereas others were not. Gamification of computer-related products and games with a numeric format tend to reduce the gap between games and computers tools and increase the conceptual synergy in such fields. Games and computer design share an opportunity for creativity and innovation to help create, specifically design, and assess preventive or therapeutic tools. Computers and games share a design conception that allows innovative approaches to overcome barriers of the real world by creating their own rules. Yet, despite the potential interest in such tools to improve treatment of mental disorders and to help prevent them, the field remains understudied and information is under-disseminated in clinical practice. Some studies have shown, however, that there is potential interest and acceptability of tools that support various vehicles, rationales, objectives, and formats. These tools include traditional games (e.g., chess games), popular electronic games, board games, computer-based interventions specifically designed for psychotherapy or cognitive training, virtual reality, apps for smartphones, and so forth. Computers and games may offer a true opportunity to develop, assess, and disseminate new prevention and treatment tools for mental health and well-being. Currently, there is a strong need for state-of-the-art information to answer questions such as the following: Why develop such tools for mental health and well-being? What are the potential additions to traditional treatments? What are the best strategies or formats to improve the possible impact of these tools? Are such tools useful as a first treatment step? What is the potential of a hybrid model of care that combines traditional approaches with games and/or computers as tools? What games and applications have already been designed and studied? What is the evidence from previous studies? How can such tools be successfully designed for mental health and well-being? What is rewarding or attractive for patients in using such treatments? What are the worldwide developments in the field? Are some protocols under development? What are the barriers and challenges related to such developments? How can these tools be assessed, and how can the way that they work, and for whom, be measured? Are the potential benefits of such products specific, or can these additions be attributed to nonspecific factors? What are the users’ views on such tools? What are the possible links between such tools and social networks? Is there a gap between evidence-based results and market development? Are there any quality challenges? What future developments and studies are needed in the field?
Author: Charles Normand
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 152
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Book Description
Author: David I. Kertzer
Publisher: Univ of California Press
ISBN: 9780520084667
Category : Social Science
Languages : en
Pages : 428
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Book Description
Thanks to improved food, medicine, and living conditions, the average age of the population is increasing throughout the modern industrialized world. Yet, despite the recent upsurge of scholarly interest in the lives of older people and the blossoming of historical demography, little historical demographic attention has been paid to the lives of the elderly. A landmark volume, Aging in the Past marks the emergence of the historical demographic study of aging. Following a masterly explication of the new field by Peter Laslett, leading scholars in family history and historical demography offer new research results and fresh analyses that greatly increase our understanding of aging, historically and across cultures. Focusing primarily on post-Industrial Europe and the United States, they explore a range of issues under the broad topics of living arrangements, widowhood, and retirement and mortality. This important work provides a much-needed historical perspective on and suggests possible alternative solutions to the problems of the aged. Thanks to improved food, medicine, and living conditions, the average age of the population is increasing throughout the modern industrialized world. Yet, despite the recent upsurge of scholarly interest in the lives of older people and the blossoming of historical demography, little historical demographic attention has been paid to the lives of the elderly. A landmark volume, Aging in the Past marks the emergence of the historical demographic study of aging. Following a masterly explication of the new field by Peter Laslett, leading scholars in family history and historical demography offer new research results and fresh analyses that greatly increase our understanding of aging, historically and across cultures. Focusing primarily on post-Industrial Europe and the United States, they explore a range of issues under the broad topics of living arrangements, widowhood, and retirement and mortality. This important work provides a much-needed historical perspective on and suggests possible alternative solutions to the problems of the aged.
Author: Marc G. Jeschke
Publisher: Springer Nature
ISBN: 3030391930
Category : Medical
Languages : en
Pages : 217
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Book Description
The second edition of this practical guide offers a comprehensive summary of the most important and most immediate therapeutic approaches in the assessment and treatment of burn injuries. Taking into account age-specific needs in pediatric, adult, and elderly burn patients, several chapters on key issues – such as pre-hospital treatment, wound care and infection control, burn nursing, critical care, burn reconstructive surgery and rehabilitation for burn victims – have now been updated. In addition, the book has been supplemented with the latest information on fluid resuscitation, organ support for burn patients, necrotizing soft tissue infections, and TEN/SJS. Written in a concise manner, the updated edition of this book provides essential guidelines for optimal care to improve patient outcomes, and thus will be a valuable reference resource for physicians, surgeons, residents, nurses, and other burn care providers.
Author: David Troyansky
Publisher: Cornell University Press
ISBN: 1501746367
Category : History
Languages : en
Pages : 281
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Book Description
This book explores a dramatic change in French attitudes toward aging and the aged in the eighteenth century from one extreme of ridicule and neglect to another of respect and care.
Author: Great Britain. Department of Health
Publisher: The Stationery Office
ISBN: 9780101626828
Category : Medical
Languages : en
Pages : 94
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Book Description
This document sets out the priorities for the NHS up to 2008 based on the process of reform set out in the NHS Plan (Cm. 4818-I ISBN 0101481829). It is in three sections. The first 'Laying the foundations' looks at the progress so far in NHS reform. The second section 'Offering a better service' sets out the objectives of the policy under the headings of personalised care, supporting people with long-term conditions, and a healthier and fitter population. One of the aims is to change the NHS from a sickness service to a service that gives a higher priority to the prevention of disease and a reduction of health inequalities. The third section is called 'Making it happen' and it covers investment and diversity of provision, staff and working practices and information systems.
Author: Colin Heywood
Publisher: John Wiley & Sons
ISBN: 1509525386
Category : History
Languages : en
Pages : 256
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Book Description
Colin Heywood's classic account of childhood from the early Middle Ages to the First World War combines a long-run historical perspective with a broad geographical spread. This new, comprehensively updated edition incorporates the findings of the most recent research, and in particular revises and expands the sections on theoretical developments in the 'new social studies of childhood', on medieval conceptions of the child, on parenting and on children’s literature. Rather than merely narrating their experiences from the perspectives of adults, Heywood incorporates children’s testimonies, 'looking up' as well as 'down'. Paying careful attention to elements of continuity as well as change, he tells a story of astonishing material improvement for the lives of children in advanced societies, while showing how the business of preparing for adulthood became more and more complicated and fraught with emotional difficulties. Rich with evocative details of everyday life, and providing the most concise and readable synthesis of the literature available, Heywood's book will be indispensable to all those interested in the study of childhood.
Author: Marc Ferro
Publisher: Wayne State University Press
ISBN: 9780814319055
Category : Performing Arts
Languages : en
Pages : 180
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Book Description
Ferro discusses how film reveals the conscious values of its creators, the dominant ideology of the society in which the film was created, and also unconscious or subverted meanings and values.
Author: Georges Minois
Publisher: University of Chicago Press
ISBN: 9780226530314
Category : History
Languages : en
Pages : 376
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Book Description
History of Old Age is the first major study of the ways in which old age has been perceived in western culture throughout history. Georges Minois paints a vast fresco, starting with the first old man to relate his own story—an Egyptian scribe some 4500 years ago—and ending with the deaths of Elizabeth I and Henry IV in the sixteenth century. Tracing the changing conceptions of the nature, value, and burden of the old, Minois argues that western history during this period is marked by great fluctuation in the social and political role of the aged. Minois shows how, in ancient Greece, the cult of youth and beauty on the one hand, and the reverence for the figure of the Homeric sage, on the other, created an ambivalent attitude toward the aged. This ambiguity appears again in the contrast between the active role that older citizens played in Roman politics and their depiction in satirical literature of the period. Christian literature in the Middle Ages also played a large part in defining society's perception of the old, both in the image of the revered holy sage and in the total condemnation of the aged sinner. Drawing on literary texts throughout, Minois considers the interrelation of literary, religious, medical, and political factors in determining the social fate of the elderly and their relationship to society. This book will be of great interest to social and cultural historians, as well as to general readers interested in the subject of the aged in society today.
