Portrait Of The Immune System, A: Scientific Publications Of N K Jerne PDF Download
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Author: Ivan Lefkovits
Publisher: World Scientific
ISBN: 981449920X
Category : Science
Languages : en
Pages : 900
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Book Description
Using the published work of Nobel Laureate Niels Kaj Jerne, this book shows how he developd his ideas. The book is a compilation of his published work, but in fact it is much more than that. Whether the reader wants to read the book systematically, or only browse, it opens a fascinating world of hypotheses, theories, facts and vistas. His selection theory, his view of how immunological diversity is created, and his concept of lymphocytes interacting as a network, reveals Jerne's revolutionary spirit. The book ought to be a rich source of inspiration for everyone interested in science and how science is made.
Author: Ivan Lefkovits
Publisher: World Scientific
ISBN: 981449920X
Category : Science
Languages : en
Pages : 900
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Book Description
Using the published work of Nobel Laureate Niels Kaj Jerne, this book shows how he developd his ideas. The book is a compilation of his published work, but in fact it is much more than that. Whether the reader wants to read the book systematically, or only browse, it opens a fascinating world of hypotheses, theories, facts and vistas. His selection theory, his view of how immunological diversity is created, and his concept of lymphocytes interacting as a network, reveals Jerne's revolutionary spirit. The book ought to be a rich source of inspiration for everyone interested in science and how science is made.
Author: Lara V. Marks
Publisher: Yale University Press
ISBN: 0300213522
Category : Medical
Languages : en
Pages : 345
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Book Description
This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.
Author: Thomas Soderqvist
Publisher: Yale University Press
ISBN: 0300128711
Category : Biography & Autobiography
Languages : en
Pages : 387
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Book Description
This biography probes the unusual mind, the dramatic life, and the outstanding scientific work of Danish-born immunologist Niels Jerne (1911–1994). Jerne’s Nobel Prize-winning achievements in the field of immunology place him in the pantheon of great twentieth-century biomedical theorists, yet his life is perhaps even more interesting than his science. Science as Autobiography tells Jerne’s story, weaving together a narrative of his life experiences, emotional life, and extraordinarily creative scientific work. A legendary figure who preferred an afternoon of conversation in a Paris wine bar to work in the laboratory, Jerne was renowned for his unparalleled powers of concentration and analytical keenness as well as his dissonant personal life. The book explores Jerne the man and scientist, making the fascinating argument that his life experience and view of himself became a metaphorical resource for the construction of his theories. The book also probes the moral issues that surrounded Jerne’s choice to sacrifice his family in favor of scientific goals and the pursuit of excellence.
Author: Gabriel Pareyón
Publisher: Gabriel Pareyon
ISBN: 9525431320
Category : Music
Languages : en
Pages : 568
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Book Description
Author: Gerald R. McMenamin
Publisher: CRC Press
ISBN: 1420041177
Category : Law
Languages : en
Pages : 358
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Book Description
Ted Kaczynski's manifesto. The ransom note for Jon Ben Ramsey. The anthrax letters threatening our government and media agencies. With the aid of forensic linguistics, the words criminals leave behind in their unsigned letters can be as distinctive as a signature or voice. Although the linguistic study of language is well established,
Author: Anca Ioviţă
Publisher: Anca Ioviţă
ISBN: 8822878795
Category : Science
Languages : en
Pages : 131
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Book Description
Aging is a puzzle to solve. This process is traditionally studied in a couple of biological models like fruit flies, worms and mice. What all these species have in common is their fast aging. This is excellent for lab budgets. It is a great short-term strategy. Who has time to study species that live for decades? But lifespan differences among species are magnitudes of order larger than any lifespan variation achieved in the lab. This is the reason for which I studied countless information resources in an attempt to gather highly specialized research into one easy-to-follow book. I wanted to see the forest among the trees. I wanted to expose the aging gap between species in an easy-to-follow and logical sequence. This book is my attempt at doing just that. What are the mechanisms underlying the aging gap between species? I intentionally chose to write the answer to this question in plain English. Aging research is too important to hide it behind the closed doors of formal scientific jargon. This book could not have existed if green tea, libraries and the Internet were not invented. The amount of data I had to browse in order to keep the essential patterns is huge. Yet this book is not exhaustive. This is not a dry academic textbook. I tried to instill life in a topic that is hugely important for the extension of human lifespan. Only you can decide if I achieved this. ********* TABLE OF CONTENTS *********** Finding the Forest Among the Trees Being Reliable Counts The Mathematics of Aging The Speed of Senescence Case Study: Aging in Fish How to Estimate Chronological Age Taking Life Slowly On Temperature and Aging Dormancy The Housekeeping Problem Case Study: Aging in Turtles Intracellular Junk Case Study: Aging in Crustaceans Extracellular Junk Case Study: Protein Quality Control The Sweet Poison Are Cell Membranes the Pacemakers of Metabolism? Could Reproduction Set up the Pacemaker of Senescence? The Segregation of Somatic and Germ Cells Clonal Senescence Versus Mechanical Senescence Same Species, Different Lifespans Case Study: Eusocial Species Case Study: Parasite/Free-Living Populations Case Study: Island Versus Inland Populations Hormones as Pacemakers of Senescence Case Study: Low Hormone Levels in Long-lived Rodents Is Aging a Form of Dehydration? The Immune Pacemaker of Senescence Innate Versus Adaptive Immunity Senescent Cells Case Study: Thymic Involution in Negligible Senescence Species Reverse Engineering the Body Case Study: Why Are Sponges Potentially Immortal? Modular Growth and Aging Case Study: Youth Is Forever Gone. Unless You Are a Hydra. Or an Immortal Jellyfish Down The Neoteny Lane Case Study: Neoteny in Amphibians Case Study: Neoteny in Mammals It's All About Neoteny Does Aging Start When Growth Stops? Case Study: Indeterminate Growth in Crustaceans The Rate of Growth Case Study: Aging in Bivalves Is Telomerase The New Fountain of Youth? Case Study: Same Species, Different Telomerase Expression Telomerase Gene Therapy Case Study: Sea Urchins Perennial Plants and Their Regenerating Roots Case Study: The Bristlecone Pine Unitary Versus Colonial Organisms Cancer The Paradox of Peto Case Study: Cancer in Long-Lived Species The End Acknowledgments Bibliography
Author: Basel Institute for Immunology
Publisher:
ISBN:
Category : Immunology
Languages : en
Pages : 304
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Book Description
Author: Robert Trappl
Publisher: World Scientific
ISBN: 9814555096
Category :
Languages : en
Pages : 1740
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Book Description
The 210 articles which are divided into 18 sections in this new reference work represent the most recent findings in cybernetics and systems research. It brings together contributions from leading scientists from all over the world — Europe, North America, South America, Asia, Africa and Australia. This volume therefore gives a broad spectrum of the ongoing research worldwide.Topics covered in the 18 sections are: General Systems Methodology; Mathematical Systems Theory; Computer Aided Process Interpretation; Fuzzy Sets, Approximate Reasoning and Knowledge-based Systems; Designing and Systems; Biocybernetics and Mathematical Biology; Cybernetics in Medicine; Cybernetics of Socioeconomic Systems; Systems, Management and Organization; Cybernetics of National Development; Communication and Computers; Connectionism and Cognitive Processing; Intelligent Autonomous Systems; Artificial Intelligence; Impacts of Artificial Intelligence.
Author: Ivan Maurice Roitt
Publisher:
ISBN:
Category : Immunity
Languages : en
Pages : 244
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Book Description
Author: Dipankar Dasgupta
Publisher: Springer Science & Business Media
ISBN: 364259901X
Category : Computers
Languages : en
Pages : 318
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Book Description
This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new information and recall previously learned information. This book provides an overview of artificial immune systems, explaining its applications in areas such as immunological memory, anomaly detection algorithms, and modeling the effects of prior infection on vaccine efficacy.
