Author: David Kessel
Publisher: Springer Science & Business Media
ISBN: 1468444069
Category : Medical
Languages : en
Pages : 296

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Book Description

Author: David Kessel
Publisher: Springer Science & Business Media
ISBN: 1461321654
Category : Science
Languages : en
Pages : 346

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Book Description
The use of porphyrins for localization and photodynamic therapy of neoplastic disease has been the topic of several international symposia, reviews and books during the preceeding five years. The literature on this topic has continued to grow, as have numbers of presentations at national and international meetings relating to photobiology, chemistry, and lasers. In this volume, it is the intention of the editor to provide both information on current research projects, and detailed methodology used in such investigations. A bibliography on the subjects of porphyrin localization and therapy is included. The manuscripts contained in this volume are based on reports given at a Porphyrin Photosensitization Workshop which was held in Philadel phia, July 6-7, 1984. This Workshop was supported by NIH grant CA 36746, together with funds from the Fogarty International Center. Authors were requested to update their contributions to provide a summary of progress to mid 1985. Manuscripts containing material not presented in Philadelphia are also included, notably a series of articles describ ing current clinical and pre-clinical results from China. Since the Philadelphia Workshop, a meeting was held in Alghero, Sardinia (May, 1985), and additional conferences are now being planned; this attests to the continued interest in photodynamic therapy involving porphyrin photo sensitization.

Author: Kendric C. Smith
Publisher: Springer Science & Business Media
ISBN: 1461580617
Category : Science
Languages : en
Pages : 429

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Book Description
The first edition of The Science of Photobiology was published in 1977, and was the first textbook to cover all of the major areas of photobiology. The science of photobiology is currently divided into 14 subspecialty areas by the American Society for Photobiology. In this edition, however, the topics of phototechnology and spectroscopy have been com bined in a new chapter entitled "Photophysics." The other subspecialty areas remain the same, i.e., Photochemistry, Photosensitization, UV Radiation Effects, Environmental Photobiology, Photomedicine, Circadian Rhythms, Extraretinal Photoreception, Vision, Photomorphogenesis, Photomovement, Photosynthesis, and Bioluminescence. This book has been written as a textbook to introduce the science of photobiology to advanced undergraduate and graduate students. The chapters are written to provide a broad overview of each topic. They are designed to contain the amount of information that might be presented in a one-to two-hour general lecture. The references are not meant to be exhaustive, but key references are included to give students an entry into the literature. Frequently a more recent reference that reviews the literature will be cited rather than the first paper by the author making the original discovery. The chapters are not meant to be a repository of facts for research workers in the field, but rather are concerned with demon strating the importance of each specialty area of photobiology, and documenting its relevance to current and/or future problems of man.

Author: Giuliana Moreno
Publisher: Springer Science & Business Media
ISBN: 3642731511
Category : Science
Languages : en
Pages : 500

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Book Description
Radiation induces a variety of chemical processes in biological tissues. This volume is a synthesis of up-to-the-minute reviews on such photochemical and photobiological sensitized reactions with particular relevance to photomedicine. The first part gives a description of experimental techniques for the study of the primary processes after radiation absorption by biological systems. It is followed by chapters on singlet oxygen and photomedicine, considering both phototherapy and photochemotherapy. These sections also discuss the next generation of potential photosensitizing drugs.

Author: David Kessel
Publisher: CRC Press
ISBN: 9780849358173
Category : Medical
Languages : en
Pages : 288

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Book Description
This two-volume text provides a summary of studies relating to the use of photosensitizing agents in the diagnosis and therapy of cancer. This interesting work describes synthesis of new sensitizers, photochemical and photobiological properties of dyes currently used for photodynamic therapy, plus those being examined with a view toward providing therapeutic advantages. It contains results and methodology from leading experts on the use of porphyrins and other photosensitizers for detection of neoplastic disease and for photodynamic therapy of neoplastic disease. The volumes focus on the major clinical and pre-clinical research groups. They also include an appended bibliography which lists all pertinent publications in this field. This easy-to-understand book is written for all workers in the field of photodynamic therapy and provides an introduction to those beginning research on some aspect of tumor photosensitization.

Author: Gregory R. Bock
Publisher: John Wiley & Sons
ISBN: 0470513853
Category : Science
Languages : en
Pages : 250

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Book Description
Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders.

Author: A. Goldberg
Publisher: Springer Science & Business Media
ISBN: 1468412779
Category : Medical
Languages : en
Pages : 382

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Book Description
Each of the four authors of this book has a particular interest in disorders of porphyrin metabolism and special experience in their management. Their individual involvement in the field varies from 12 to 52 years and, combined, represents more than a century of personal experience. Since it has been written by both basic scientists and practicing physicians, the book is intended to be of value to all those involved in porphyrin metab olism and the porphyrias. It is hoped that the fascination of porphyrin metabolism and the clinical challenge of the porphyrias experienced by each of the authors will be conveyed to the readers. Michael R. Moore Kenneth E. L. McColl Claude Rimington Abraham Goldberg vii CONTENTS Color Plates ............................................ xvii 1. The History, Classification, and Incidence of the Porphyrias 1 1.1. History ........................................ 1 1.1.1. Early Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1.2. Early Descriptions of Porphyria .............. 4 1.1.3. Biochemical Developments .................. 4 1.1.4. Acute Porphyria . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.5. A Complete Pathway ...................... 8 1.2. Classification of the Porphyrias . . . . . . . . . . . . . . . . . . . . . 9 1.2.1. The Current Classification. . . . . . . . . . . . . . . 12 . . . .

Author: R. Cubeddu
Publisher: Springer Science & Business Media
ISBN: 1468447211
Category : Science
Languages : en
Pages : 442

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Book Description
This book contains the contributions of the participants to the International Symposium on Porphyrins in Tumor Phototherapy held in Bruzzano (Milano), Italy on May 26-28, 1983. The contributions are written as extended papers to provide a broad and representative coverage of the use of porphyrins in tumor phototherapy and diagnosis. In the last few years, this technique has received increasing interest for its potential applications in clinical oncology. In fact, 1,500 patients have been already treated by this therapy which has been tested in more than 100 clinical centres. Among the reported cases, a significant therapeutic effectiveness was found in some early stage cancers of lung, esophagus and stomach. The development of ·this therapy requires interdisciplinary studies from such diverse fields as physics, chemistry, biology, pharmacology, and experimental and clinical oncology. The contents of the book reflect the character of this research and deal with all the problems, from fundamental to clinical, that still require to be analysed and understood for a better evaluation 'of the potential of this therapy. The first chapter of the book deals with photophysics ?;nd.

Author: Sangwan Lee
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 348

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Author: F. Hillenkamp
Publisher: Springer Science & Business Media
ISBN: 1468485504
Category : Technology & Engineering
Languages : en
Pages : 463

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Book Description
This volume contains the lectures and seminars presented at the NATO Advanced Study Institute on Lasers in Biology and Medicine organized by the International School of Quantum Electronics at the Villa Le Pianore, Camaiore, Italy, August 19-31, 1979. Most laser applications in biology and medicine are highly interdisciplinary in nature, drawing from and pertaining to such diverse fields as the physical sciences ( (bio)physics, (bio)chemi stry) , engineering, the biological sciences (cellular research, photobiology) and finally theoretical and clinical medicine. Indeed the group of participants of the summer school did reflect this diversity both in background and interest. The presentations con tained in this volume mainly fall into two categories: tutorial lectures on the most important general subjects, intended to lay a common base for all participants, and a number of more advanced con tributions, serving the purpose of exemplifying selected but typical applications in their current state of development. Intense inter communication, lively discussion, and here and there even future cooperation were the general aims more than a detailed in-depth discussion of one or the other aspect of this large field. In this sense it is the hope of the organizing committee that, despite the inevitable limitations, a broad and reasonably representative cov erage of the field has been achieved and that this volume may be a valuable aid for newcomers to get a good start into this complex subject area for some years to corne.