Polarized Light in Biomedical Imaging and Sensing

Polarized Light in Biomedical Imaging and Sensing PDF Author: Jessica C. Ramella-Roman
Publisher: Springer Nature
ISBN: 3031047419
Category : Technology & Engineering
Languages : en
Pages : 362

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Book Description
This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.

Polarized Light in Biomedical Imaging and Sensing

Polarized Light in Biomedical Imaging and Sensing PDF Author: Jessica C. Ramella-Roman
Publisher: Springer Nature
ISBN: 3031047419
Category : Technology & Engineering
Languages : en
Pages : 362

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Book Description
This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.

Optical Polarization in Biomedical Applications

Optical Polarization in Biomedical Applications PDF Author: Valery V. Tuchin
Publisher: Springer Science & Business Media
ISBN: 3540453210
Category : Science
Languages : en
Pages : 281

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Book Description
Optical Polarization in Biomedical Applications introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues. This theory uses the modified transfer equation for Stokes parameters and predicts the polarization structure of multiple scattered optical fields. The backscattering polarization matrices (Jones matrix and Mueller matrix) important for noninvasive medical diagnostic are introduced. The text also describes a number of diagnostic techniques such as CW polarization imaging and spectroscopy, polarization microscopy and cytometry. As a new tool for medical diagnosis, optical coherent polarization tomography is analyzed. The monograph also covers a range of biomedical applications, among them cataract and glaucoma diagnostics, glucose sensing, and the detection of bacteria.

Bioimaging

Bioimaging PDF Author: Shoogo Ueno
Publisher: CRC Press
ISBN: 0429536569
Category : Medical
Languages : en
Pages : 273

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Book Description
Bioimaging: Imaging by Light and Electromagnetics in Medicine and Biology explores new horizons in biomedical imaging and sensing technologies, from the molecular level to the human brain. It explores the most up-to-date information on new medical imaging techniques, such as the detection and imaging of cancer and brain diseases. This book also provides new tools for brain research and cognitive neurosciences based on new imaging techniques. Edited by Professor Shoogo Ueno, who has been leading the field of biomedical imaging for 40 years, it is an ideal reference book for graduate and undergraduate students and researchers in medicine and medical physics who are looking for an authoritative treatise on this expanding discipline of imaging and sensing in medicine and biology. Features: Provides step-by-step explanations of biochemical and physical principles in biomedical imaging Covers state-of-the art equipment and cutting-edge methodologies used in biomedical imaging Serves a broad spectrum of readers due to the interdisciplinary topic and approach Shoogo Ueno, Ph.D, is a professor emeritus of the University of Tokyo, Tokyo, Japan. His research interests include biomedical imaging and bioelectromagnetics, particularly in brain mapping and neuroimaging, transcranial magnetic stimulation (TMS), and magnetic resonance imaging (MRI). He was the President of the Bioelectromagnetics Society, BEMS (2003-2004) and the Chairman of the Commission K on Electromagnetics in Biology and Medicine of the International Union of Radio Science, URSI (2000-2003). He was named the IEEE Magnetics Society Distinguished Lecturer during 2010 and received the d’Arsonval Medal from the Bioelectromagnetics Society in 2010.

Optical Polarimetric Modalities for Biomedical Research

Optical Polarimetric Modalities for Biomedical Research PDF Author: Nirmal Mazumder
Publisher: Springer Nature
ISBN: 3031318528
Category : Science
Languages : en
Pages : 455

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Book Description
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.

Biomedical Optical Sensors

Biomedical Optical Sensors PDF Author: Richard De La Rue
Publisher: Springer Nature
ISBN: 3030483878
Category : Technology & Engineering
Languages : en
Pages : 243

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Book Description
This book provides wide-ranging coverage of current developments in biomedical sensing based on photonic techniques. Biomedical sensing is a dynamic topic that promises to deliver much in the future evolution of medical diagnostics, delivering advanced tools for fundamental research in biology at the micrometre and nanometre scales. The book explores a variety of alternative physical and biological methodologies that have become available for application, such as plasmonic sensors and photonic crystal biosensors. At the same time, it addresses issues that potentially limit the capability of biomedical optical sensing techniques, while reviewing the state-of-the-art in biomedical optical sensing for the future work that will lead to near-universal applications of such techniques. Edited and written by leading experts in this domain, this book is ideal as a comprehensive manual for researchers and graduate students.

Coherent-Domain Optical Methods

Coherent-Domain Optical Methods PDF Author: Valery V. Tuchin
Publisher: Springer Science & Business Media
ISBN: 1402075766
Category : Technology & Engineering
Languages : en
Pages : 963

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Book Description
For the first time in one set of books, coherent-domain optical methods are discussed in the framework of various applications, which are characterized by a strong light scattering. A few chapters describe basic research containing the updated results on coherent and polarized light non-destructive interactions with a scattering medium, in particular, diffraction, interference, and speckle formation at multiple scattering. These chapters allow for understanding coherent-domain diagnostic techniques presented in later chapters. A large portion of Volume I is dedicated to analysis of various aspects of optical coherence tomography (OCT) - a very new and growing field of coherent optics. Two chapters on laser scanning confocal microscopy give insight to recent extraordinary results on in vivo imaging and compare the possibilities and achievements of confocol, excitation multiphoton, and OCT microscopy. This two volume reference contains descriptions of holography, interferometry and optical heterodyning techniques in their application for diagnostics of turbid materials. The most prospective methods of coherent and polarization optical imaging and spectroscopy, including polarization-sensitive optical coherent tomography, polarization diffusion wave spectroscopy, and elastic and quasi-elastic light scattering spectroscopies and image techniques, are presented.

Biophotonics

Biophotonics PDF Author: Gerd Keiser
Publisher: Springer Nature
ISBN: 9811934827
Category : Science
Languages : en
Pages : 409

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Book Description
This book introduces senior-level and postgraduate students to the principles and applications of biophotonics. It also serves as a valuable reference resource or as a short-course textbook for practicing physicians, clinicians, biomedical researchers, healthcare professionals, and biomedical engineers and technicians dealing with the design, development, and application of photonics components and instrumentation to biophotonics issues. The topics include the fundamentals of optics and photonics, the optical properties of biological tissues, light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of tissue, and optical biomedical imaging. It also describes tools and techniques such as laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), optical imaging modalities, photodynamic therapy (PDT), photobiostimulation or low-level light therapy (LLLT), diverse microscopic and spectroscopic techniques, tissue characterization, laser tissue ablation, optical trapping, and optogenetics. Worked examples further explain the material and how it can be applied to practical designs, and the homework problems help test readers’ understanding of the text. This second edition provides updates as follows: 1) Updated references in each chapter with recent review papers, tutorials, and generic research results. 2) New sections in Chap. 3 addressing tapered fibers for sensors, biocompatibility issues of optical fibers, and concepts of implantable fibers. 3) Updates in Chaps. 4 and 5 on optical sources and photodetectors discussing fiber-based sources, silicon photomultipliers, and high-speed cameras for biosensing. 4): Sections on improvements in microscopy, imaging, spectroscopy, and sensing in Chapters 7–10. 5) New biophotonic application techniques in Chap. 11 will include optogenetic advances, smart phones for imaging, wearable biophotonic sensors, and robotic surgery and light therapy.

Wavefront Shaping for Biomedical Imaging

Wavefront Shaping for Biomedical Imaging PDF Author: Joel A. Kubby
Publisher:
ISBN: 9781316403938
Category : HEALTH & FITNESS
Languages : en
Pages :

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Book Description
"The most common approach to adaptive optics (AO), as originally employed in astronomical telescopes, has been to use a wavefront sensor to measure directly aberrations. In situations where such sensing provides reliable measurement, this is clearly the ideal method (see Chapter 2), but this approach has limitations, and particularly so in the context of microscopy. In order to understand this, one should consider the constraints the use of a wavefront sensor places on the nature of the optical conguration. A wavefront is only well de ned in particular situations, for example when light is emitted by a small or distant, point-like object, such as a star for a telescope or a minuscule bead in a microscope. In these situations, a wavefront sensor provides a clear and reliable measurement and this phenomenon has been used to great effect, as explained in Chapter 2. However, not all sources of light have these necessary properties. For example, a large luminous object comprises an arrangement of individual emitters, each of which produces its associated wavefront. In this case, a wavefront sensor would respond to all of the light impinging upon it, thus giving potentially ambiguous measurements. In an extreme case, such as where light is emitted throughout the volume of the specimen, the sensor would be swamped with light and thus be un-able to provide sensible aberration measurement. For this reason, in microscopy, direct wavefront sensing has been e ective where point-like sources have been employed, either through the introduction of uorescent beads [1, 2], or using localised uorescent markers [3] and non-linear excited guide stars [4, 5, 6]"--Provided by publisher.

Biological Imaging and Sensing

Biological Imaging and Sensing PDF Author: Toshiyuki Furukawa
Publisher: Springer Science & Business Media
ISBN: 3662060817
Category : Medical
Languages : en
Pages : 312

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Book Description
An excellent survey of and introduction to new methods of biological imaging and sensing, particularly related to biomedical measurements and controls. The main topics discussed include: cell imaging, multiphoton microscopy for biomedical studies, molecular imaging, infrared imaging, biomedical magnetic imaging, and microscopy with laser-trapped particles. The book also deals with nanosurgery with light, the effects of ultrasound on tissue, diagnostics, near- and far-infrared transmission of biomedical information, and cell sensors. This book will be a valuable resource for both medical doctors and biophysicists.

Handbook of Coherent-Domain Optical Methods

Handbook of Coherent-Domain Optical Methods PDF Author: Valery V. Tuchin
Publisher: Springer
ISBN: 9781461451754
Category : Science
Languages : en
Pages : 1332

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Book Description
This Handbook provides comprehensive coverage of laser and coherent-domain methods as applied to biomedicine, environmental monitoring, and materials science. Worldwide leaders in these fields describe the fundamentals of light interaction with random media and present an overview of basic research. The latest results on coherent and polarization properties of light scattered by random media, including tissues and blood, speckles formation in multiple scattering media, and other non-destructive interactions of coherent light with rough surfaces and tissues, allow the reader to understand the principles and applications of coherent diagnostic techniques. The expanded second edition has been thoroughly updated with particular emphasis on novel coherent-domain techniques and their applications in medicine and environmental science. Volume 1 describes state-of-the-art methods of coherent and polarization optical imaging, tomography and spectroscopy; diffusion wave spectroscopy; elastic, quasi-elastic and inelastic light scattering spectroscopy and imaging; digital holographic microscopy, the Fourier transform light scattering method, and coherent diffractive imaging; wavefront sensing, aberration measurement and adaptive optics for ophthalmology; and laser remote sensing. Volume 2 presents the new and growing field of coherent optics in optical coherence tomography (OCT). Various applications of OCT and confocal microscopy, including biomedical endoscopy, are discussed. A special section covers Mueller matrix polarimetry, nonlinear laser fluorescence spectroscopy, and triplet-triplet annihilation assisted upconversion as optical tools for probing the physical parameters of materials and natural organic compounds.