Phenothiazines and 1,4-benzothiazines

Phenothiazines and 1,4-benzothiazines PDF Author: Radha Raman Gupta
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 1024

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Phenothiazines and 1,4-benzothiazines

Phenothiazines and 1,4-benzothiazines PDF Author: Radha Raman Gupta
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 1024

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Phenothiazines and 1,4- Benzothiazines

Phenothiazines and 1,4- Benzothiazines PDF Author: Radha Raman Gupta
Publisher:
ISBN: 9780444426338
Category : Phenothiazine
Languages : en
Pages : 1000

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Thiophene Analogues of Phenothiazine Neuroleptics

Thiophene Analogues of Phenothiazine Neuroleptics PDF Author: Harm Rollema
Publisher:
ISBN:
Category : Antipsychotic drugs
Languages : en
Pages : 110

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Ring Systems Handbook

Ring Systems Handbook PDF Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 2100

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Host-Guest-Systems Based on Nanoporous Crystals

Host-Guest-Systems Based on Nanoporous Crystals PDF Author: Franco Laeri
Publisher: John Wiley & Sons
ISBN: 3527605223
Category : Science
Languages : en
Pages : 687

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Book Description
Interest in nanoporous crystals as host-guest systems has risen dramatically over the past few years, such that this fascinating class of substances now plays an important role not only in material sciences, but also in numerous other disciplines, such as organic or supramolecular chemistry. With their unique characteristics, nanoporous crystals offer a wide range of possible applications: They are used as molecular sieves or membranes as well as catalytic converters. This work presents the very first overview of this exciting field. Readers will find everything they need to know about these unusual materials, with all their many attributes: · Synthesis of host-guest systems · Description of the structural and dynamic aspects · Electronic and optical characteristics of the materials · Possible applications. An indispensable reference for materials scientists as well as for catalytic and inorganic chemists, and all those working in the field.

Key Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules PDF Author: Om Silakari
Publisher: Elsevier
ISBN: 0081021054
Category : Science
Languages : en
Pages : 438

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Book Description
Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. - Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules - Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents - Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

The Essence of Analgesia and Analgesics

The Essence of Analgesia and Analgesics PDF Author: Raymond S. Sinatra
Publisher: Cambridge University Press
ISBN: 1139491989
Category : Medical
Languages : en
Pages : 551

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Book Description
The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Parent Compound Handbook

Parent Compound Handbook PDF Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 772

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Synthesis of Essential Drugs

Synthesis of Essential Drugs PDF Author: Ruben Vardanyan
Publisher: Elsevier
ISBN: 008046212X
Category : Medical
Languages : en
Pages : 635

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Book Description
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

Bioactive Heterocyclic Compound Classes

Bioactive Heterocyclic Compound Classes PDF Author: Clemens Lamberth
Publisher: John Wiley & Sons
ISBN: 3527664475
Category : Science
Languages : en
Pages : 367

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Book Description
The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures. Often, these compounds show beneficial properties and are therefore applied as pharmaceuticals to treat diseases or as insecticides, herbicides or fungicides in crop protection. This volume presents important pharmaceuticals. Each of the 20 chapters covers in a concise manner one class of heterocycles, clearly structuredas follows: * Structural formulas of most important examples (market products) * Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References. A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the pharmaceutical chemistry.