Pharmacology for Chemists PDF Download
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Author: Joseph G. Cannon
Publisher: American Chemical Society
ISBN: 0841239274
Category : Language Arts & Disciplines
Languages : en
Pages : 335
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Book Description
The book is intended for chemists entering medicinal chemistry research who have no knowledge of pharmacology. Pharmacological principles and concepts are emphasized, rather than a survey of large numbers of specific drugs. It is intended to serve as a tool to prepare the reader for further in-depth study in many areas of pharmacology.
Author: Joseph G. Cannon
Publisher: American Chemical Society
ISBN: 0841239274
Category : Language Arts & Disciplines
Languages : en
Pages : 335
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Book Description
The book is intended for chemists entering medicinal chemistry research who have no knowledge of pharmacology. Pharmacological principles and concepts are emphasized, rather than a survey of large numbers of specific drugs. It is intended to serve as a tool to prepare the reader for further in-depth study in many areas of pharmacology.
Author: Raymond Hill
Publisher: Royal Society of Chemistry
ISBN: 1782621423
Category : Medical
Languages : en
Pages : 538
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Book Description
This textbook explains the key issues in pharmacology to chemists interested in or planning to work in drug discovery.
Author: David G. Watson
Publisher: Elsevier Health Sciences
ISBN: 0702069884
Category : Medical
Languages : en
Pages : 598
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Book Description
Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. - Worked calculation examples - Self-assessment - Additional problems (self tests) - Practical boxes - Key points boxes - New chapter on electrochemical biosensors. - New chapter on the quality control of biotechnologically produced drugs. - Extended chapter on molecular emission spectroscopy. - Now comes with an e-book on StudentConsult. - Self-assessment is interactive in the accompanying online e-book. - 65 online animations show concepts such as ionization partitioning of drug molecules etc. - ~
Author: Goutam Brahmachari
Publisher: CRC Press
ISBN: 1439891672
Category : Medical
Languages : en
Pages : 586
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Book Description
Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure–activity relationships.
Author: Camille Georges Wermuth
Publisher: Elsevier
ISBN: 0080497772
Category : Science
Languages : en
Pages : 792
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Book Description
The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. - The only book available dealing with the practical aspects of medicinal chemistry - Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production - Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry
Author: Francis Francis
Publisher:
ISBN:
Category : Pharmaceutical chemistry
Languages : en
Pages : 400
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Book Description
Author: Patrick Schnider
Publisher: Royal Society of Chemistry
ISBN: 1839160497
Category : Science
Languages : en
Pages : 541
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Book Description
The Medicinal Chemist’s Guide to Solving ADMET Challenges summarizes a series of design strategies and tactics that have been successfully employed across pharmaceutical and academic laboratories to solve common ADMET issues. These are exemplified with a curated collection of concrete examples displayed in a highly visual “table-of-contents” style format, allowing readers to rapidly identify the most promising approaches applicable to their own challenges. Each ADMET parameter is introduced in a concise yet comprehensive manner and includes background, relevance and screening strategies. Medicinal chemistry knowledge of how best to modify molecular structure to solve ADMET issues is challenging to retrieve from the literature, public databases and even corporate data warehouses. The Medicinal Chemist’s Guide to Solving ADMET Challenges addresses this gap by presenting state-of-the-art design strategies put together by a global group of experienced medicinal chemists and ADMET experts across academia and the pharmaceutical industry.
Author: Camille Georges Wermuth
Publisher: Elsevier
ISBN: 012417213X
Category : Science
Languages : en
Pages : 903
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Book Description
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com
Author: Lemont Kier
Publisher: Elsevier
ISBN: 0323158315
Category : Science
Languages : en
Pages : 272
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Book Description
Medicinal Chemistry, Volume 14: Molecular Connectivity in Chemistry and Drug Research is a 10-chapter text that focuses on the molecular connectivity approach for quantitative evaluation of molecular structure of drugs. Molecular connectivity is a nonempirical derivation of numerical value that encode within them sufficient information to relate to many physicochemical and biological properties. This book outlines first the development of molecular connectivity approach, followed by considerable chapters on its application to evaluation of physicochemical properties of drugs. Other chapters explore the application of molecular connectivity to structure-activity studies in medicinal chemistry. The final chapters provide some reflections, challenges, and potential areas of investigation of molecular connectivity. Advanced undergraduate or graduate students in medicinal chemistry or pharmacology, practicing scientists, and theoretical chemists will find this book invaluable.
Author: Katya Tsaioun
Publisher: John Wiley & Sons
ISBN: 0470922818
Category : Medical
Languages : en
Pages : 454
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Book Description
This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.
