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Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 488
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Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 488
Get Book Here
Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 012398467X
Category : Science
Languages : en
Pages : 1504
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Book Description
Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. - Explores neuronal protection by polyphenol metabolites and their application to medical care - Defines modulation of enzyme actions to help researchers see and study polyphenols' mechanisms of action, leading to clinical applications - Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases
Author: Jianxun Liu
Publisher: Frontiers Media SA
ISBN: 2889717984
Category : Science
Languages : en
Pages : 227
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Book Description
Cardiovascular diseases include ischemic and hemorrhagic diseases involving the heart, brain, whole body tissue, and includes coronary heart disease, heart failure, arrhythmia, atherosclerosis and stroke. This particular group of diseases continue to be a leading cause of death throughout the world with mortality rate remaining high. Currently, drugs administered orally and intravenously and surgical treatments are used to treat such diseases. Traditional Chinese medicine (TCM) refers to natural herbal medicines and their processed products used for preventing and treating disease under the guidance of traditional Chinese medicine’s theory. The implementation of prevention and treatment programs of ischemic cardiovascular diseases with the use of TCM have been associated with positive outcomes; in terms of a reduction in the disability and mortality rate of some patients. Other studies have also shown that specific multi-component TCM preparations have therapeutic benefits based on multi-target and multi-pathway mechanisms, which may have advantages over the current single-component and single-target therapy. Based these characteristics, approved pharmaceutical drugs based in TCM, such as Compound Danshen Dripping Pills, Naoxintong Capsules, Tonxinluo Capsules, and Danhong Injection, are currently used to treat cardiovascular diseases. However, there are a number of areas that still need further investigation. For example, the identification of effective components in herbal medicine is essential in furthering our understanding of what occurs at a pharmacological level; the metabolizing pharmacological pathways of such components; the cellular target of the components; and the lack of standardized guidelines to enhance clinical research.
Author: Salah Abdel-aleem
Publisher: Springer Science & Business Media
ISBN: 1461556872
Category : Science
Languages : en
Pages : 192
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Book Description
This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.
Author: Qingren Wang
Publisher: Blue Poppy Enterprises, Inc.
ISBN: 9781891845390
Category : Medical
Languages : en
Pages : 546
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Book Description
Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
ISBN: 3540898905
Category : Medical
Languages : en
Pages : 576
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Book Description
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Author: Xijun Wang
Publisher: Academic Press
ISBN: 0128031182
Category : Science
Languages : en
Pages : 408
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Book Description
Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. - Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method - Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications - Edited by the leading experts of research related to Chinmedomics
Author: Jehrod Brenneman
Publisher: Royal Society of Chemistry
ISBN: 1839160519
Category : Medical
Languages : en
Pages : 364
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Book Description
Fibrosis is a condition with globally high unmet medical need, and as such is a highly active area of academic and pharmaceutical research covering multiple treatment targets, organs, tissues and therapeutic approaches. Anti-fibrotic Drug Discovery is a single source reference for the latest drug-discovery approaches to tackle fibrosis in various tissues, comprehensively covering recent success and future perspectives on emerging therapeutic intervention points. The book highlights significant pre-clinical and clinical drugs currently being developed globally for this disorder. This book is ideal for postgraduate students and researchers with an interest in anti-fibrotic drug discovery as well as clinicians specialising in liver, kidney, heart and lung disease, in which fibrosis plays a key role in pathology.
Author: Ying Xia
Publisher: Springer Science & Business Media
ISBN: 3642108571
Category : Medical
Languages : en
Pages : 490
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Book Description
Acupuncture therapy has been practiced in China and other Asian countries for more than two thousand years. Modern clinical research has confirmed the impressive therapeutic effect of acupuncture on numerous human ailments, such as controlling pain, nausea, and vomiting. However, the biological mechanisms of acupuncture are still under debate. In Traditional Chinese Medicine (TCM), the mechanism of acupuncture therapy is explained by a meridian model. According to this model, acupuncture is believed to treat the diseased organs by modulating two conditions known as Yin and Yang, which represent all the opposite principles that people find in the universe, both inside and outside the human body. Yin and Yang complement each other, and are subjected to changes between each other. The balance of Yin and Yang is thought to be maintained by Qi, an energy substance flowing constantly through the meridian, a network connecting all the organs of the body. The illness, according to this theory, is the temporary dominance of one principle over the other, owing to the blockade of the Qi from flowing through the meridian under certain circumstance. The axiom of “No stagnation, No pain” in TCM summarizes this concept. Thus, the goal of acupuncture treatment is to restore the balance of Yin and Yang conditions in the diseased organ(s). This theory has been considered to be useful to guide this ancient therapy, such as carrying out diagnosis, deciding on the principle, and selecting the acupoints.
Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 0821361805
Category : Medical
Languages : en
Pages : 1449
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Book Description
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
