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Author: Dario Giardina
Publisher: Elsevier
ISBN: 0080545017
Category : Science
Languages : en
Pages : 423
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Book Description
Perspectives in Receptor Research
Author: Dario Giardina
Publisher: Elsevier
ISBN: 0080545017
Category : Science
Languages : en
Pages : 423
Get Book Here
Book Description
Perspectives in Receptor Research
Author: Mostafa Z. Badr
Publisher: Springer Nature
ISBN: 3030783154
Category : Medical
Languages : en
Pages : 676
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Book Description
Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address the various means and consequences of modulating nuclear receptor activity will be presented and discussed. These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.
Author: David Blum
Publisher: Academic Press
ISBN: 9780128037249
Category : Science
Languages : en
Pages : 0
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Book Description
Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.
Author: Arthur N. Popper
Publisher: Springer Science & Business Media
ISBN: 1461491029
Category : Medical
Languages : en
Pages : 668
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Book Description
Perspectives on Auditory Research celebrates the last two decades of the Springer Handbook in Auditory Research. Contributions from the leading experts in the field examine the progress made in auditory research over the past twenty years, as well as the major questions for the future.
Author: Rongrong Fan
Publisher: Frontiers Media SA
ISBN: 2889743292
Category : Medical
Languages : en
Pages : 206
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Book Description
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1340
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Sylvia B. Smith
Publisher: Springer
ISBN: 3319501747
Category : Medical
Languages : en
Pages : 311
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Book Description
Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.
Author: Lee E. Limbird
Publisher: Springer Science & Business Media
ISBN: 9780792338390
Category : Medical
Languages : en
Pages : 260
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Book Description
Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.
Author: Peter Illes
Publisher: John Wiley & Sons
ISBN:
Category : Medical
Languages : en
Pages : 560
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Book Description
Author: Yi Ma
Publisher: Frontiers Media SA
ISBN: 288945973X
Category :
Languages : en
Pages : 192
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Book Description
