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Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
Get Book Here
Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author: Pere Ginès
Publisher: Springer Science & Business Media
ISBN: 1607618664
Category : Medical
Languages : en
Pages : 583
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Book Description
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Author: Lanjuan Li
Publisher: Springer Nature
ISBN: 9811559848
Category : Medical
Languages : en
Pages : 571
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Book Description
This book introduces the clinical application of artificial liver system (ALS) in hepatic failure. It has been widely used in clinics aiming to provide temporary support of liver function while maintaining extra-hepatic function in patients with liver failure. This work comprehensively summarizes the progress of livers and artificial liver, for example, the principle and implementation of Li-ALS, cell transplantation and the combined application of artificial liver and liver transplantation. It will be helpful for clinicians to implement artificial liver treatment to save the lives of patients with hepatic failure.
Author: D. Keppler
Publisher: Springer Science & Business Media
ISBN: 9401166188
Category : Medical
Languages : en
Pages : 316
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Book Description
The pathogenesis of cell death and necrosis in the liver is a central topic of research in liver disease. A molecular understanding of events and sequences leading to cellular death provides the basis for preventive and therapeutic efforts. This volume originates from a "Workshop on Experimental Liver Injury" held on November 9 and 10, 1974, in Freiburg, Germany. Recent progress in the elucidation of the mode of action includes agents inducing liver cell necrosis by a primary dis turbance of nucleotide and nucleic acid metabolism as well as hepa totoxins characterized by a primary attack on cellular membranes. I hope that this book will contribute to an increasing understanding of disease mechanisms. Freiburg im Breisgau Dietrich Keppler June 1975 Acknowledgments The generous support from Dr. H. Falk, Freiburg, has been a prereqUIsite for the organisation and publication of the meeting on "Pathogenesis and Mechanisms of Liver Cell Necrosis". I wish to express my sincere thanks for this sponsorship. I am indebted to those who acted as chairmen during the meeting: Professors H. Remmer (Tilbingen), M. Frimmer (Giessen), W. Gerok (Freiburg), H. Popper (New York), H. Schimassek (Heidelberg), and K. Decker (Freiburg).
Author: Peter Joseph Scheuer
Publisher:
ISBN:
Category : Biopsy
Languages : en
Pages : 208
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Book Description
Author: M. Eric Gershwin
Publisher: Springer Science & Business Media
ISBN: 331902096X
Category : Medical
Languages : en
Pages : 482
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Book Description
Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.
Author: Frederick J. Suchy
Publisher: Cambridge University Press
ISBN: 1139464035
Category : Medical
Languages : en
Pages : 995
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Book Description
Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.
Author: Alastair D. Burt
Publisher: Elsevier Health Sciences
ISBN: 0323508693
Category : Medical
Languages : en
Pages : 1067
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Book Description
Since its first publication more than 35 years ago, MacSween’s Pathology of the Liver, by Drs. Alastair D. Burt, Linda D. Ferrell, and Stefan G. Hübscher, has established itself as the definitive reference on liver pathology. The 7th Edition continues the tradition of excellence with more than 1,000 high-quality illustrations, coverage of the new and emerging diagnostic applications and techniques that pathologists must be familiar with, an up-to-date review of drug-induced injury, and much more. A must-have for every surgical pathologist, MacSween’s remains the most authoritative and comprehensive book in its field. Provides comprehensive, state-of-the-art coverage of all malignant and benign hepatobiliary disorders from an international "who’s who" in the field. Helps you quickly recognize the wide variety of liver appearances that result from infections, tumors, and tumor-like lesions, as well as organ damage caused by drugs and toxins. Features 1,000+ full-color illustrations that provide a complete visual guide to each tumor or tumor-like lesion and assist in the recognition and diagnosis of any tissue sample you’re likely to encounter. Incorporates relevant data from ancillary techniques (immunohistochemistry, cytogenetics, and molecular genetics), giving you the tools required to master the latest breakthroughs in diagnostic technology. Includes an updated chapter on mechanisms of liver disease, including coverage of regression and remodeling of disease and new information on next generation sequencing; an up-to-date review of drug-induced injury, including the effects of herbal and alternative medicines. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Author: John L. Atlee
Publisher: Elsevier Health Sciences
ISBN: 1416022155
Category : Medical
Languages : en
Pages : 1030
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Book Description
Practical text focuses on complications in the practice of anesthesia. Divided into sections similar to the thought processes involved in decision-making. Thumb indexing and cross-references are also included. All chapters have a case synopsis, problem analysis, and discussion of management and prevention.
Author: Han-Ming Shen
Publisher: Springer Science & Business Media
ISBN: 1461482208
Category : Science
Languages : en
Pages : 402
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Book Description
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
