Part I. The Intramolecular Nitrile Oxide Cycloaddition Route to Spirocyclic Alkaloids. A Total Synthesis of Isonitramine and Sibirine PDF Download
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Author: Po-wai Yuen
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 356
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Book Description
Author: Po-wai Yuen
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 356
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Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 468
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Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 754
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Book Description
Author: Kocvosky
Publisher: CRC Press
ISBN:
Category : Science
Languages : en
Pages : 300
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Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 606
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Author: American Chemical Society, Committee on Professional Training Staff
Publisher:
ISBN: 9780841214187
Category : Science
Languages : en
Pages : 1390
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Author:
Publisher:
ISBN:
Category : Heterocyclic compounds
Languages : en
Pages : 420
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Author: Orazio A. Attanasi
Publisher:
ISBN: 9788886208567
Category : Science
Languages : en
Pages : 0
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Book Description
Volume 11 keeps the international standard of the THS series, covering the synthesis, reactivity, activity (including medicinal) and mass spectrometry of different systems.
Author: B.E. Maryanoff
Publisher: Elsevier
ISBN: 0080526373
Category : Science
Languages : en
Pages : 338
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Book Description
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
