Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition PDF Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117

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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition PDF Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117

Get Book Here

Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Oxygen Transport to Tissue-V

Oxygen Transport to Tissue-V PDF Author: D. W. Lubbers
Publisher: Springer Science & Business Media
ISBN: 1468411888
Category : Nature
Languages : en
Pages : 893

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Book Description
On the understanding that few people ever read the preface to any book and also on the understanding that even those few people who do read the preface realize that virtually nothing of any substance is ever said, I shall write at such length as will be proportional to my expected readership. The meetings of the International Society on Oxygen Transport to Tissue provide a forum for discussion amongst scientists who, although being from very diverse and specialized backgrounds, have tissue oxygenation as a unifying theme of interest. The wide variety of research material presented in this volume and the multiplicity of the experimental techniques described, should serve as an adequate gauge to the range of expertise and knowledge of the society's members. Such diversity should also stress the importance of the need for multidisciplinary approaches to complex biological problems. In attempting a fundamental characterization of a biological process such as tissue oxygenation, the application of very many separate research skills are necessary, such as mathematics, engi neering, biophysics, biochemistry, physiology, histology and clini cal medicine. The success of the ISOTT has - and we hope - will con tinue to be causing a combination of individuals to direct their specialized knowledge to the many facets of a single proces- tissue oxygenation.

Oxygen Transport to Tissue-V

Oxygen Transport to Tissue-V PDF Author: D W Lubbers
Publisher: Springer
ISBN: 9781468411898
Category :
Languages : en
Pages : 960

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Book Description


Oxygen Transport to Tissue—VI

Oxygen Transport to Tissue—VI PDF Author: Duane F. Bruley
Publisher: Springer Science & Business Media
ISBN: 1468448951
Category : Nature
Languages : en
Pages : 903

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Book Description
The theme of the 1983 annual ISOTT meeting emphasizes a dual scientific approach, utilizing interdisciplinary theoretical and experimental methodology, to unravel the secrets of oxygen transport to tissue. ISOTT is leading the way in the development and application of forefront techniques to allow a more basic understanding of this important physiological phenomena. The Society can be proud of its contributions in helping to advance the gross analysis techniques of the past to the synergistic study of tissue micro areas by sophisticated mathematical and experimental means. There is a tremendous need to continue the pursuit of basic knowledge at the regional tissue level and to move rapidly to the examination of fundamental biochemical reactions at the cellular level. To accomplish this, it will be necessary to take advantage of the most powerful computing machinery presently available and to apply state-of-the-art experimental methodology, such as polarographic, autoradiographic and nuclear magnetic resonance techniques in our studies. Our Society must continue to work hard to push back barriers to enhance our understanding of mechanisms that lead to pathology. Hopefully, our efforts will be significant in helping science to overcome the many dreadful diseases that mankind faces in today's world. Duane Bruley Haim Bicher Daniel Reneau v ACKNOWLEDGEMENT We are forever indebted to Connie Staggs and Ellie Topakoglu for their energy and sacrifice in preparing for and managing the 1983 ISOTT meeting.

Oxygen Transport to Tissue XXV

Oxygen Transport to Tissue XXV PDF Author: Maureen S. Thorniley
Publisher: Springer Science & Business Media
ISBN: 1475761252
Category : Science
Languages : en
Pages : 325

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Book Description
The 30th scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) was held at the Western Conference Centre, UMIST, Manchester, in August 2002. It was attended by some 96 delegates and accompanying persons and there were 128 presentations.

Oxygen Transport to Tissue XXIV

Oxygen Transport to Tissue XXIV PDF Author: Jeffrey Dunn
Publisher: Springer Science & Business Media
ISBN: 1461500753
Category : Science
Languages : en
Pages : 728

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Book Description
This volume contains refereed manuscripts prepared from presentations made at the 2ih annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT). The meeting was held in Hanover, NH, USA, at Dartmouth Medical School, the 3rd oldest medical school in the USA. ISOTT attempts to produce high quality pUblications on cutting edge topics relating to oxygen in living systerns. The goal is to allow contributors to contribute original data, as with a main-stream journal article, but also to voice individual opinions and ideas in a more relaxed scientific forum. The meeting brought together an international group of scientists who share a common interest in the measurement and role of oxygen in living systems. The organizers of ISOTT99 made a special effort to bring together people from industry, medicine, and basic sciences in order to improve the links in the chain of discovery through to application. As a result, this volume contains publications on a range of subjects. There are contributions from companies on modifiers of oxygen carrying capacity (allosteric modifiers of hemoglobin and infusible oxygen carriers or blood substitutes); technical reports on oxygen measurement devices including advances in near-infrared spectroscopy and imaging, oxygen electrodes, magnetic resonance spectroscopy and imaging, and fluorescence based measurements. There are medically related sections on modifying and measuring tumor oxygenation in order to improve therapy, assessment and interpretation of oxygenation in the central nervous system, and general issues relating oxygen to pathological conditions.

Oxygen Transport to Tissue XXXI

Oxygen Transport to Tissue XXXI PDF Author: Eiji Takahashi
Publisher: Springer Science & Business Media
ISBN: 144191241X
Category : Science
Languages : en
Pages : 555

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Book Description
The International Society on Oxygen Transport to Tissue (ISOTT, www. isott. info) is an interdisciplinary society comprising about 250 members worldwide. Its purpose is to further the understanding of all aspects of the processes involved in the transport of oxygen from the air to its ultimate consumption in the cells of the various organs of the body. The annual meeting brings together scientists, engineers, clinicians and mathematicians in a unique int- national forum for the exchange of information and knowledge, the updating of participants on latest developments and techniques, and the discussion of controversial issues within the field of oxygen transport to tissue. Founded in 1973, the society has been the leading platform for the presentation of many of the technological and conceptual developments within the field both at the meetings themselves and in the proceedings of the society. These have been published first by Plenum Publishing (1973), then by Kluwer Academic/Plenum Publishers and presently by Springer Publishing, all in the Advances In Expe- mental Medicine and Biology Series. The 36th Annual ISOTT conference was held in Sapporo, Japan during August 3–7, 2008. It was the second occasion that the ISOTT meeting was held in Japan; the first one was held in the same place in 1987 organized by Professor Masaji Mochizuki.

Oxygen Transport to Tissue XL

Oxygen Transport to Tissue XL PDF Author: Oliver Thews
Publisher: Springer
ISBN: 3319912879
Category : Medical
Languages : en
Pages : 452

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Book Description
The book contains the refereed contributions from the 45th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) 2017. This volume covers cross-disciplinary work on a broad range of topics related to the dynamics of oxygen transport: microcirculation and vascular medicine; O2 deficiency and its impact on molecular processes in cells and tissues; cellular metabolism and mitochondrial function; multimodal functional imaging; mathematical modeling; the clinical relevance of oxygen supply as well as therapeutic interventions (e.g. in oncology or critical care medicine). The annual meetings of ISOTT bring together scientists from diverse fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. The book includes sections on brain oxygenation and function, NIRS oxygenation measurements, tumor oxygenation, cell metabolism, tissue oxygenation and treatment, methodical aspects of O2 measurements and physicochemical aspects of oxygen diffusion. Chapters 3, 24, 49 and 51 of this book are open access under a CC BY 4.0 license.

Oxygen transport to tissue

Oxygen transport to tissue PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Oxygen Transport to Tissue XXVII

Oxygen Transport to Tissue XXVII PDF Author: Giuseppe Cicco
Publisher: Springer Science & Business Media
ISBN: 0387295402
Category : Science
Languages : en
Pages : 393

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Book Description
This book covers the proceedings of the 32nd scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) in Bari, Italy, August 21-26, 2004. It covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special emphasis is placed on methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. The event hosted was a multidisciplinary meeting designed to bring together experts and students from a range of research fields.