OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070729
Category :
Languages : en
Pages : 9

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Book Description
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070729
Category :
Languages : en
Pages : 9

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Book Description
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070702
Category :
Languages : en
Pages : 16

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Book Description
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...

OECD Guidelines for the Testing of Chemicals

OECD Guidelines for the Testing of Chemicals PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070680
Category :
Languages : en
Pages : 13

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Book Description
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071202
Category :
Languages : en
Pages : 18

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Book Description
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure PDF Author: OECD
Publisher: OECD Publishing
ISBN: 926407094X
Category :
Languages : en
Pages : 14

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Book Description
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071229
Category :
Languages : en
Pages : 20

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Book Description
The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071180
Category :
Languages : en
Pages : 15

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Book Description
The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071008
Category :
Languages : en
Pages : 14

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Book Description
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070923
Category :
Languages : en
Pages : 7

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Book Description
This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic ...