OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 116: Fat Solubility of Solid and Liquid Substances

OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 116: Fat Solubility of Solid and Liquid Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264069801
Category :
Languages : en
Pages : 7

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Book Description
This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method ...

OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 116: Fat Solubility of Solid and Liquid Substances

OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 116: Fat Solubility of Solid and Liquid Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264069801
Category :
Languages : en
Pages : 7

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Book Description
This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method ...

OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices (GIVIMP)

OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices (GIVIMP) PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264304797
Category :
Languages : en
Pages : 206

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Book Description
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...

Test No. 109: Density of Liquids and Solids

Test No. 109: Density of Liquids and Solids PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264069666
Category :
Languages : en
Pages : 5

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Book Description
This Test Guideline lists methods for determining the density of liquids and solids, giving only a very succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in kg/m3. Several methods ...

Human and Ecological Risk Assessment

Human and Ecological Risk Assessment PDF Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
ISBN: 1119551102
Category : Technology & Engineering
Languages : en
Pages : 1319

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Book Description
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.

OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002

OECD Guidelines for the Testing of Chemicals OECD Guidelines for the Testing of Chemicals Fourteenth Addendum - May 2002 PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264170200
Category :
Languages : en
Pages : 79

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Book Description
The OECD Guidelines for the Testing of Chemicals provide a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as the standard methods for safety testing, the OECD Guidelines for ...

OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 114: Viscosity of Liquids

OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 114: Viscosity of Liquids PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264185186
Category :
Languages : en
Pages : 6

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Book Description
This Test Guideline describes methods to measure the viscosity of liquids. Most of the methods listed are appropriate for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is possible with the rotational viscometer ...

Introduction to Toxicological Screening Methods and Good Laboratory Practice

Introduction to Toxicological Screening Methods and Good Laboratory Practice PDF Author: Saravana Babu Chidambaram
Publisher: Springer Nature
ISBN: 9811660921
Category : Medical
Languages : en
Pages : 205

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Book Description
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.

OECD Guidelines for the Testing of Chemicals / Section 1: Physical-Chemical properties Test No. 102: Melting Point/ Melting Range

OECD Guidelines for the Testing of Chemicals / Section 1: Physical-Chemical properties Test No. 102: Melting Point/ Melting Range PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264069526
Category :
Languages : en
Pages : 9

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Book Description
This Test Guidelines describes several methods and devices to determine the temperature or temperature range of the phase transition from the solid to the liquid state or from the liquid to the solid state. The melting point is defined as the ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070761
Category :
Languages : en
Pages : 9

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Book Description
This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...

Test No. 114: Viscosity of Liquids

Test No. 114: Viscosity of Liquids PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264069763
Category :
Languages : en
Pages : 7

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Book Description
This Test Guideline describes methods to measure the viscosity of liquids. The methods listed are appropriate in principle for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is only possible with the rotational ...