Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders

Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders PDF Author: Aasef G. Shaikh
Publisher: Frontiers Media SA
ISBN: 2889455637
Category :
Languages : en
Pages : 247

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Book Description
Eye movements provide rich source of information about brain functioning for neurologists and neuroscientists. They provide diagnostic clues, define, and localize motor and cognitive disorders. Objective eye movement assessments associated with clinical observation and genetic testing in neurodegenerative, neurometabolic, and neurogenetic diseases provide insight into their pathophysiology and disease mechanism. Finally the eye movements may be used for testing and following the response to therapies. The concrete value of studying eye movement stems from a number of advantages compared to the study of movements of axial or limb muscles. The eye movements are accessible to clinical inspection, they can be measured precisely, their interpretation is clear and therefore ocular motility examination has high localization value. There are several standardized tasks to study of each subclass of eye movements that are recognized for motor or cognitive behavior. Indeed the studies of eye movement had allowed test of motor and cognitive functions of the brain in a vast range of neurological disease. Both cortical and subcortical dysfunctions may be detected with the analysis of subclasses of eye movements and interpreted in association with other clinical, laboratory and neuroimaging features. The goal of this topic-focused volume of Frontiers in Neurology is to gather seminal studies, from well-known scientists and laboratories from across the world, delineating the features of eye movements and vestibular system in neurogenetic, neurometabolic, and neurodegenerative disorders. Such collection of articles, to our knowledge, is unique and never done in the past. The topics and the compilation will be of interest to broad groups of neuroscientists and neurologists for the reasons as follows: 1) Neurodegenerative diseases represent a large portion of neurological diseases encountered in neurological clinical practice. Eye movement changes may occur early in their course and may be specific, thus orienting the diagnosis. 2) Neurometabolic and neurogenetic conditions, although rare, show specific and characteristic eye movements that represent the hallmark of the disease. Such disorders often represent a pathologic model that helps to understand the normal functioning of specific brain regions and networks.

Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders

Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders PDF Author: Aasef G. Shaikh
Publisher: Frontiers Media SA
ISBN: 2889455637
Category :
Languages : en
Pages : 247

Get Book Here

Book Description
Eye movements provide rich source of information about brain functioning for neurologists and neuroscientists. They provide diagnostic clues, define, and localize motor and cognitive disorders. Objective eye movement assessments associated with clinical observation and genetic testing in neurodegenerative, neurometabolic, and neurogenetic diseases provide insight into their pathophysiology and disease mechanism. Finally the eye movements may be used for testing and following the response to therapies. The concrete value of studying eye movement stems from a number of advantages compared to the study of movements of axial or limb muscles. The eye movements are accessible to clinical inspection, they can be measured precisely, their interpretation is clear and therefore ocular motility examination has high localization value. There are several standardized tasks to study of each subclass of eye movements that are recognized for motor or cognitive behavior. Indeed the studies of eye movement had allowed test of motor and cognitive functions of the brain in a vast range of neurological disease. Both cortical and subcortical dysfunctions may be detected with the analysis of subclasses of eye movements and interpreted in association with other clinical, laboratory and neuroimaging features. The goal of this topic-focused volume of Frontiers in Neurology is to gather seminal studies, from well-known scientists and laboratories from across the world, delineating the features of eye movements and vestibular system in neurogenetic, neurometabolic, and neurodegenerative disorders. Such collection of articles, to our knowledge, is unique and never done in the past. The topics and the compilation will be of interest to broad groups of neuroscientists and neurologists for the reasons as follows: 1) Neurodegenerative diseases represent a large portion of neurological diseases encountered in neurological clinical practice. Eye movement changes may occur early in their course and may be specific, thus orienting the diagnosis. 2) Neurometabolic and neurogenetic conditions, although rare, show specific and characteristic eye movements that represent the hallmark of the disease. Such disorders often represent a pathologic model that helps to understand the normal functioning of specific brain regions and networks.

Advances in Translational Neuroscience of Eye Movement Disorders

Advances in Translational Neuroscience of Eye Movement Disorders PDF Author: Aasef Shaikh
Publisher: Springer Nature
ISBN: 3030314073
Category : Medical
Languages : en
Pages : 513

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Book Description
A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson - one of the pioneers of contemporary ocular motor and vestibular neuroscience.

Eye Movement Disorders

Eye Movement Disorders PDF Author: E.A.C.M. Sanders
Publisher: Springer Science & Business Media
ISBN: 9400933177
Category : Medical
Languages : en
Pages : 276

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Book Description
There is perhaps no area of neuro-ophthalmology that is advancing more rapidly with respect to an understanding of its anatomy and physiology than the ocular motor system. For this reason, it is difficult not only to keep up with the latest information concerning the basic mechanisms involved in the control of eye movements but also to remain up to date regarding the pathophysiology of specific disorders of eye movement. The material in this book is derived from a two-day course on eye movements held in The Netherlands in 1986. The course was designed as an introduction to the normal ocular motor system and to disorders of eye movements and was aimed toward orthoptists, ophthalmolo gists, optometrists, neurologists, and neurosurgeons. The chapters in this book were compiled by a trio of experts in the field of eye movements and contain discussions of anatomy and physiology of the ocular motor system, techniques of examination of patients with diplopia, and pathophysiology of specific disorders of ocular motility. Many of the authors of these chapters are among the most active investigators of eye movements in the world today, and their comments thus reflect the latest information in the field. This text is both basic and com prehensive and thus has something for everyone, from the student just beginning a study of the ocular motor system to the seasoned 'veteran' who wishes to know the latest information regarding central ocular motor control mechanisms. Neil R.

Pediatric Neuro-Ophthalmology

Pediatric Neuro-Ophthalmology PDF Author: Michael C. Brodsky
Publisher: Springer Science & Business Media
ISBN: 1461384575
Category : Medical
Languages : en
Pages : 692

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Book Description
Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.

Neuroanatomy Text and Atlas, Fifth Edition

Neuroanatomy Text and Atlas, Fifth Edition PDF Author: John D. Martin
Publisher: McGraw Hill Professional
ISBN: 1259642496
Category : Medical
Languages : en
Pages : 542

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Book Description
A regional and functional approach to learning human neuroanatomy – enhanced by additional full-color illustrations and PowerPoint® slides of all images in the text for instructors! Neuroanatomy: Text and Atlas covers neuroanatomy from both a functional and regional perspective to provide an understanding of how the components of the central nervous system work together to sense the world around us, regulate body systems, and produce behavior. This trusted text thoroughly covers the sensory, motor, and integrative skills of the brains and presents an overview of the function in relation to structure and the locations of the major pathways and neuronal integrative regions. Neuroanatomy: Text and Atlas also teaches readers how to interpret the new wealth of human brain images by developing an understanding of the anatomical localization of brain function. The authoritative core content of myelin-stained histological sections is enhanced by informative line illustrations, angiography, and brain views produced by MRI, and other imaging technologies. • Revised and updated to reflect advances in clinical neuroanatomy and neural science • Full-color illustrations enrich the text, including many new to this edition • Chapters begin with a clinical case to illustrate the connections and functions of the key material • Chapters end with a series of multiple-choice review questions • NEW Online learning center will display brain views produced by MRI and PET • Increases knowledge of the regional and functional organization of the spinal cord and brain, one system at a time • Provides thorough coverage of the sensory, motor, and integrative systems of the brain, together with cerebral vasculature • Promotes understanding of the complex details of neuroanatomy needed for accurate interpretation of radiological image • Comprehensive atlas provides key views of the surface anatomy of the central nervous systems and photographs of myelin-stained sections in three anatomical planes • Includes learning aids such as clinical topics, boxes, chapter summaries, and a Glossary of key terms and structures

Eye Tracking Methodology

Eye Tracking Methodology PDF Author: Andrew Duchowski
Publisher: Springer Science & Business Media
ISBN: 1846286093
Category : Computers
Languages : en
Pages : 336

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Book Description
Despite the availability of cheap, fast, accurate and usable eye trackers, there is little information available on how to develop, implement and use these systems. This 2nd edition of the successful guide contains significant additional material on the topic and aims to fill that gap in the market by providing an accessible and comprehensive introduction. Additional key features of the 2nd edition include: Technical description of new (state-of-the-art) eye tracking technology; a complete whole new section describing experimental methodology including experimental design, empirical guidelines, and five case studies; and survey material regarding recent research publications.

The 5-Minute Neurology Consult

The 5-Minute Neurology Consult PDF Author: D. Joanne Lynn
Publisher: Lippincott Williams & Wilkins
ISBN: 1451100124
Category : Medical
Languages : en
Pages : 485

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Book Description
This volume in the 5-Minute Consult series focuses on neurological diseaes and disorders, as well as key symptoms, signs, and tests. Dozens of noted authorities provide tightly organized, practical guidance. Using the famous two-page layout and outline format of The 5-Minute Consult Series, the book provides instant access to clinically-oriented, must-have information on all disorders of the nervous system. Each disease is covered in a consistent, easy-to-follow format: basics (including signs and symptoms), diagnosis, treatment, medications, follow-up, and miscellaneous considerations (including diseases with similar characteristics, pregnancy, synonyms, and ICD coding).

Clinical Neurology, 3Ed

Clinical Neurology, 3Ed PDF Author: T.J. Fowler
Publisher: CRC Press
ISBN: 0340807989
Category : Medical
Languages : en
Pages : 597

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Book Description
The third edition of this concise but comprehensive textbook follows on from the highly-regarded earlier editions in providing the trainee and general physician with a better understanding of the principles of neurology. Retaining an emphasis on the core clinical skills of history taking and careful neurological examination, the new edition has been thoroughly revised and updated to take into account new developments in investigation and treatment. Particular areas of enhanced coverage include headache, expanded beyond migraine to cover other presentations, and multiple sclerosis. Completely new chapters discuss the increasing role of neurogenetics in the understanding and treatment of neurological disease, the importance of pain and its management and neurological complications associated with respiratory intensive care. Following the sad death of Dr. David Marsden, Dr John Scadding has joined the editorial team retaining the 'Queen Square' connection of earlier editions.

Traumatic Brain and Spinal Cord Injury

Traumatic Brain and Spinal Cord Injury PDF Author: Cristina Morganti-Kossmann
Publisher: Cambridge University Press
ISBN: 1107007437
Category : Medical
Languages : en
Pages : 361

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Book Description
Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

The Neuronal Ceroid Lipofuscinoses (Batten Disease)

The Neuronal Ceroid Lipofuscinoses (Batten Disease) PDF Author: Sara Mole
Publisher: OUP Oxford
ISBN: 019101558X
Category : Medical
Languages : en
Pages : 772

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Book Description
The neuronal ceroid lipofuscinoses are an extremely rare group of inherited neurodegenerative diseases that primarily affect children. Core symptoms of these conditions typically include epilepsy, cognitive decline and visual failure. These diseases are so rare that professionals who come into contact with them need a consultative reference work that enables them to become expert, or identify who to contact for more details. Fully updated and revised, this second edition continues to be the definitive volume on this devastating group of disorders. Written by an international collection of authorities in the field, it provides invaluable advice on their diagnosis, patient care, and new treatments that are available. This new edition of the definitive reference text on the neuronal ceroid lipofuscinoses will prove useful for clinicians, family physicians, research scientists, diagnostic laboratories, families affected by the disease as well as by workers in industry planning translational research.