Novel Therapies for CNS Injuries

Novel Therapies for CNS Injuries PDF Author: Patti L. Peterson
Publisher: CRC Press
ISBN: 9780849376528
Category : Medical
Languages : en
Pages : 426

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Book Description
This book provides reviews of the epidemiology, evaluation, and patient management of central nervous system (CNS) injuries. Internationally recognized clinicians and basic scientists discuss recent research that has significantly advanced the understanding of the pathophysiology of neuronal death and facilitated development of new therapeutic approaches. Novel therapeutic agents evaluated in animal models and currently in clinical trials include: calcium antagonists glutamate receptor antagonists inhibitors of glutamate release endothelial adhesion and nerve growth factors opioids antioxidants, gangliosides thrombolytic agents All of these options, as well as hypothermia as a potentially therapeutic approach, are discussed in this comprehensive volume. It will be invaluable to neurologists, neurosurgeons, intensivists, and emergency medicine physicians who care for CNS injured patients.

Novel Therapies for CNS Injuries

Novel Therapies for CNS Injuries PDF Author: Patti L. Peterson
Publisher: CRC Press
ISBN: 9780849376528
Category : Medical
Languages : en
Pages : 426

Get Book Here

Book Description
This book provides reviews of the epidemiology, evaluation, and patient management of central nervous system (CNS) injuries. Internationally recognized clinicians and basic scientists discuss recent research that has significantly advanced the understanding of the pathophysiology of neuronal death and facilitated development of new therapeutic approaches. Novel therapeutic agents evaluated in animal models and currently in clinical trials include: calcium antagonists glutamate receptor antagonists inhibitors of glutamate release endothelial adhesion and nerve growth factors opioids antioxidants, gangliosides thrombolytic agents All of these options, as well as hypothermia as a potentially therapeutic approach, are discussed in this comprehensive volume. It will be invaluable to neurologists, neurosurgeons, intensivists, and emergency medicine physicians who care for CNS injured patients.

Brain Neurotrauma

Brain Neurotrauma PDF Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine PDF Author: António Salgado
Publisher: Elsevier
ISBN: 0128180854
Category : Medical
Languages : en
Pages : 712

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Book Description
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury PDF Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388

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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Sports-Related Concussions in Youth

Sports-Related Concussions in Youth PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309288037
Category : Medical
Languages : en
Pages : 215

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Book Description
In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.

Experimental and Clinical Approaches in the Pursuit of Novel Therapeutic Strategies for Perinatal Brain Injury and its Neurological Sequelae

Experimental and Clinical Approaches in the Pursuit of Novel Therapeutic Strategies for Perinatal Brain Injury and its Neurological Sequelae PDF Author: Changlian Zhu
Publisher: Frontiers Media SA
ISBN: 2889718026
Category : Science
Languages : en
Pages : 213

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Book Description


Acquired Brain Injury

Acquired Brain Injury PDF Author: Jean Elbaum
Publisher: Springer
ISBN: 3030166139
Category : Psychology
Languages : en
Pages : 367

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Book Description
This book presents a comprehensive interdisciplinary team approach to the rehabilitation of acquired brain injury (ABI) survivors. Medical and clinical specialists will receive a deeper understanding of not only each other’s roles but of their complementary functions in this field. Many case examples are provided, illustrating a wide range of challenges and stages of recovery. This edition features 3 entirely new chapters and multiple updated chapters by new and returning authors. Featured in the coverage: The role of Robotics in acquired brain injury A comprehensive chapter on physical therapy in ABI Outstanding recoveries woven together by a video news producer who recovered from a meningioma State of the art updates on neurosurgery, neurology, physiatry, neuropsychiatry and neuro-optometry. Updated chapters on neuropsychology, speech-language and occupational therapies including new technology and approaches as well as evidence based practices Psychosocial challenges and treatment following ABI The importance of family as team members Post rehabilitation options and experiences Acquired Brain Injury: An Integrative Neuro-Rehabilitation Approach, 2nd edition provides clarity and context regarding the rehabilitation goals and processes for rehabilitation specialists, interdisciplinary students of neuro-rehabilitation as well as practicing clinicians interested in developing their knowledge in their field.

Over My Head

Over My Head PDF Author: Claudia L. Osborn
Publisher: Andrews McMeel Publishing
ISBN: 9780740705984
Category : Humor
Languages : en
Pages : 260

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Book Description
Hit by a car while bicycling Osborn, an internist at a Detroit hospital, suffered injuries. Recounts the struggles and frustrations of a gradually learning strategies to compensate for the lack of certain brain functions. An exceptionally well-written and engaging account. PW review.

Head Cases

Head Cases PDF Author: Michael Paul Mason
Publisher: Macmillan + ORM
ISBN: 1429953748
Category : Biography & Autobiography
Languages : en
Pages : 320

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Book Description
A case manager shares stories of patients’ and families’ journeys and “deftly conveys the frustrations and inequities of traumatic brain injury” (Mary Roach, The New York Times Book Review). Head Cases takes us into the dark side of the brain in an astonishing sequence of stories, at once true and strange, about the effects of brain damage. Michael Paul Mason is one of an elite group of experts who coordinate care in the complicated aftermath of tragic injuries that can last a lifetime. On the road with Mason, we encounter survivors of brain injuries as they struggle to map and make sense of the new worlds they inhabit. Underlying each of these survivors’ stories is an exploration of the brain and its mysteries. When injured—by a bad fall, a viral infection, or some other misfortune—the brain must figure out how to heal itself, reorganizing its physiology in order to do the job. Mason gives us a series of vivid glimpses into brain science, the last frontier of medicine, and we come away in awe of the miracles of the brain’s workings and astonished at the fragility of the brain and the sense of self, life, and order that resides there. Head Cases “[achieves] through sympathy and curiosity insight like that which pulses through genuine literature” (The New York Sun); it is at once illuminating and deeply affecting. “Vivid, heartbreaking [and] movingly written.” —The Seattle Times “Tells stories of tremendous courage and perseverance as survivors and their families work to re-establish the everyday skills they had before their injury. The strange effects of neurological damage will draw fans of Oliver Sacks, but Mason’s poignant and caring accounts of his clients’ lives are sure to touch the hearts of a wide range of readers.” —Publishers Weekly (starred review)

Rights Come to Mind

Rights Come to Mind PDF Author: Joseph Fins
Publisher: Cambridge University Press
ISBN: 052188750X
Category : Law
Languages : en
Pages : 395

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Book Description
Joseph J. Fins calls for a reconsideration of severe brain injury treatment, including discussion of public policy and physician advocacy.