Novel Methods for Nitrogen-Containing Heterocycles and Applications to Total Synthesis PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Novel Methods for Nitrogen-Containing Heterocycles and Applications to Total Synthesis PDF full book. Access full book title Novel Methods for Nitrogen-Containing Heterocycles and Applications to Total Synthesis by Patrick Daniel Parker. Download full books in PDF and EPUB format.
Author: Patrick Daniel Parker
Publisher:
ISBN:
Category :
Languages : en
Pages : 249
Get Book Here
Book Description
Author: Patrick Daniel Parker
Publisher:
ISBN:
Category :
Languages : en
Pages : 249
Get Book Here
Book Description
Author: Ana Maria Faisca Phillips
Publisher: John Wiley & Sons
ISBN: 1119708796
Category : Science
Languages : en
Pages : 1370
Get Book Here
Book Description
A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research. This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones. Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids Discusses how to synthesize rings of specific sizes Covers sustainable synthetic approaches for obtaining salts Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.
Author: Jacques Royer
Publisher: John Wiley & Sons
ISBN: 3527625518
Category : Science
Languages : en
Pages : 425
Get Book Here
Book Description
Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications. Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.
Author: Matthew Paul Brichacek
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
A single synthetic method rarely is sufficient to provide universal access to a chemical structure class. This realization forces organic chemists to devise and develop new methods. The copper catalyzed ring expansion of vinylaziridines produces nitrogen containing heterocycles commonly found in pharmaceuticals and natural products. This reaction is described from its initial discovery, through optimization, to application. Many substitution patterns and functional groups were tested and the reaction was found to be quite tolerant. By controlling the aziridine and olefin stereochemistry the selective synthesis of either cis or trans 2,5dihydropyrroles was achieved. Likewise, vinyloxiranes were stereoselectively converted to cis- or trans-2,5-dihydrofurans. Furthermore, the asymmetric synthesis of 2-substituted-2,5-dihydrofurans was achieved using chirality transfer characteristic of a [1,3]- sigmatropic rearrangement. This method was further tested by completing the total synthesis of natural products goniothalesdiol and varitriol.
Author: Gianfranco Favi
Publisher: MDPI
ISBN: 3036503404
Category : Medical
Languages : en
Pages : 372
Get Book Here
Book Description
Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.
Author: Ana Maria Faisca Phillips
Publisher: John Wiley & Sons
ISBN: 1119757126
Category : Science
Languages : en
Pages : 759
Get Book Here
Book Description
More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.
Author: Arife Yazici
Publisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 180
Get Book Here
Book Description
Author: Hyun-Joon Ha
Publisher: Frontiers Media SA
ISBN: 2832549187
Category : Science
Languages : en
Pages : 101
Get Book Here
Book Description
Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.
Author: Navjeet Kaur
Publisher: CRC Press
ISBN: 1000733416
Category : Science
Languages : en
Pages : 404
Get Book Here
Book Description
Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.
Author: Navjeet Kaur
Publisher: Elsevier
ISBN: 0128202831
Category : Science
Languages : en
Pages : 526
Get Book Here
Book Description
Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Highlights new methodologies for the synthesis of different six-membered heterocycles Provides an up-to-date overview of this fast-moving field with an easy-to-use structure Includes novel approaches used in the study and application of catalysts in synthetic organic reactions
