Novel Approaches to the Synthesis of Quinoline Derivatives PDF Download
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Author: Phindile Jonathan Klaas
Publisher:
ISBN:
Category : Quinoline
Languages : en
Pages : 202
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Book Description
Author: Phindile Jonathan Klaas
Publisher:
ISBN:
Category : Quinoline
Languages : en
Pages : 202
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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![Rearrangements in the Indolo[2,3-b]quinoline System PDF](https://books.google.com/books/content/images/frontcover/eESC0AEACAAJ?fife=w80-h100)
Author: Nicholas Voûte
Publisher:
ISBN:
Category : Claisen rearrangement
Languages : en
Pages : 0
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Author: B. P. Nandeshwarappa
Publisher:
ISBN: 9781839690037
Category :
Languages : en
Pages : 202
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Author: S'busiso Mfan'vele Nkosi
Publisher:
ISBN:
Category : Cell-mediated cytotoxicity
Languages : en
Pages : 308
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Author: Rajesh Y B R D
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
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Book Description
Among heterocyclic compounds, quinoline is a privileged scaffold that appears as an important construction motif for the development of new drugs. Quinoline nucleus is endowed with a variety of therapeutic activities, and new quinolone derivatives are known to be biologically active compounds possessing several pharmacological activities. Many new therapeutic agents have been developed by using quinoline nucleus. Hence, quinoline and its derivatives form an important class of heterocyclic compounds for the new drug development. Numerous synthetic routes have been developed for the synthesis of quinoline and its derivatives due to its wide range of biological and pharmacological activities. The article covers the synthesis as well as biological activities of quinoline derivatives such as antimalarial, anticancer, antibacterial, anthelmintic, antiviral, antifungal, anti-inflammatory, analgesic, cardiovascular, central nervous system, hypoglycemic, and miscellaneous activities.
Author: Luisa Savini
Publisher:
ISBN:
Category :
Languages : en
Pages : 21
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Author: V. Vijayakumar
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659202148
Category :
Languages : en
Pages : 248
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Book Description
Quinoline heterocycles found to have diverse biological activities and 3-functionalised quinolines are important intermediates for the synthesis of various quinoline derivatives. 3-acetyl-4-hydroxy-quinolin-2(1H)-one and 6-chloro-3-acetyl-4-phenyl-2-methyl quinoline were chosen as intermediates for the synthesis of some novel quinoline derivatives. In particular, only a few methods are available for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-one, which involve either two step or multistep reaction protocols. In the present work, a rapid, efficient and one pot procedure for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-ones has been developed both by conventional and microwave assisted synthesis. The 3-acetyl quinolines were converted into chalcones which in turn converted to quinoline-3-yl pyrazolines and quinoline-3-yl isoxazolines and a few into 3-(2, 4-substitutedstyryl)isoxazolo[4,5-c]quinolin-4(5H)-ones. These compounds were explored for their anti-microbial and cyctotoxicity studies.
Author: Michael J. Davis
Publisher:
ISBN:
Category : Cubitene
Languages : en
Pages : 256
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Author: P. L. Loke
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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