Novel Antipsychotic Drugs PDF Download
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Author: Herbert Y. Meltzer
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 296
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Book Description
Contains highlights of an American College of Neuropsychopharmacology conference on new directions in the development of atypical and other novel antipsychotic drugs. Presents new theories and preclinical and clinical data on various drugs and classes of drugs including amperozide and other drugs.
Author: Herbert Y. Meltzer
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 296
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Book Description
Contains highlights of an American College of Neuropsychopharmacology conference on new directions in the development of atypical and other novel antipsychotic drugs. Presents new theories and preclinical and clinical data on various drugs and classes of drugs including amperozide and other drugs.
Author: Thomas R.E. Barnes
Publisher: Academic Press
ISBN: 1483288102
Category : Medical
Languages : en
Pages : 304
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Book Description
In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547693
Category : Medical
Languages : en
Pages : 80
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Book Description
This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Author: Kathleen Degen
Publisher: Jason Aronson
ISBN:
Category : Medical
Languages : en
Pages : 266
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Book Description
Shedding the lifelong identity of a mental patient, they no longer need case management but require help adjusting to major changes in their thinking and functioning. Kathleen Degen and Ellen Nasper describe group therapy that helps patients identify and cope with unexpected, intense feelings such as sadness or painful memories of childhood trauma, increase their interpersonal skills, and advance their sense of self beyond that of their label as mental patients.
Author: Katherine J. Aitchison
Publisher: CRC Press
ISBN: 9781853174353
Category : Medical
Languages : en
Pages : 152
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Book Description
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.
Author: Stephen M. Stahl
Publisher: Cambridge University Press
ISBN: 0521149053
Category : Medical
Languages : en
Pages : 203
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Book Description
Concepts are illustrated by full-color images that will be familiar to all readers of Stahl's Essential Psychopharmacology, 3rd Edition and The Prescriber's Guide.
Author: Vijay K. Shukla
Publisher:
ISBN: 9781894620055
Category : Antipsychotic drugs
Languages : en
Pages : 33
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Book Description
The purpose of this assessment is to assess the efficacy of the novel antipsychotic drugs (olanzapine, risperidone, quetiapine and clozapine) both as monotherapy and as add-on therapy for acute and maintenance treatment of bipolar disorder. A systematic review was performed of clinical trials in which a novel antipsychotic drug was compared prospectively with placebo or with another agent for treatment of patients with bipolar disorder. Too little information is currcntly available to draw any meaningful conclusions concerning the use of novel antipsychotics in the treatment of bipolar disorder. Given the high cost of these agents, and the lack of conclusive evidence concerning their benefit over traditional therapies, a cautious approach is warranted when considering their use. This is a rapidly changing field and other trials with new information will soon be completed.
Author: Peter Haddad
Publisher: Oxford University Press
ISBN: 0191045780
Category : Medical
Languages : en
Pages : 266
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Book Description
Antipsychotic Long-acting Injections (LAIs) were introduced in the 1960s to improve treatment adherence in schizophrenia. Subsequently, first-generation antipsychotic LAIs became widely used in many countries. Since the initial publication of Antipsychotic Long-acting Injections in 2010, new trial data have been published on long-acting injection (LAI) preparations of the drugs Risperidone, Paliperidone, and Olanzapine. Furthermore, a new LAI preparation of the drug Aripiprazole has recently been approved for clinical use in the United States and is likely to be approved in Europe soon. The second edition of this successful book has been fully updated to include this new data, with reference to both observational studies and randomized controlled trials, as well as other new developments in the clinical use of antipsychotic LAIs. New chapters have been added covering the comparison between oral and injectable antipsychotics, Olanzapine LAI, Aripiprazole LAI, and the practicalities of organizing a specialized clinic for long-acting injectable antipsychotics. Existing chapters have also been thoroughly updated to take into account the most recently published research. Antipsychotic Long-acting Injections, Second edition brings together clinical and research findings on LAIs in a comprehensive volume, with chapters written by international experts.
Author: Bart A. Ellenbroek
Publisher: Birkhäuser
ISBN: 3034884486
Category : Medical
Languages : en
Pages : 239
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Book Description
The introduction of chlorpromazine in 1953, and haloperidol in 1958, into clinical practice dramatically altered the therapy of schizophrenic patients. Although representing by no means a cure for this severe psychiatric ill ness, it allowed, for the first time, to adequately control the severe hallu cinations and delusional beliefs which prevent these patients from leading a more or less independent life. Indeed these antipsychotics (and the many congeners that were to follow) significantly reduced the number ofchronic schizophrenic inpatients in psychiatric clinics all over the world. However soon after their introduction it became clear that, like all other available drugs, antipsychotics were by no means miracle drugs. In fact, two major problems appeared. First, the antipsychotics had very little effect on the so-called negative or defect symptoms, like social isolation, apathy and anhedonia, and secondly virtually all antipsychotics produced a number of side-effects, of which the neurological (often called extra pyramidal) side-effects were the most troublesome. Especially the tardive dyskinesia, which occurred in about 15 to 20% of the patients after pro longed treatment, represented a major problem in the treatment of schizo phrenic patients.
Author: Peter Manu
Publisher: Academic Press
ISBN: 0128033908
Category : Medical
Languages : en
Pages : 396
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Book Description
Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations
