Nora Virus Infection of Drosophila Melanogaster

Nora Virus Infection of Drosophila Melanogaster PDF Author: Ethan Cordes
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 138

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Nora Virus Infection of Drosophila Melanogaster

Nora Virus Infection of Drosophila Melanogaster PDF Author: Ethan Cordes
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 138

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The Role of Vago in Drosophila Melanogaster Nora Virus Infection

The Role of Vago in Drosophila Melanogaster Nora Virus Infection PDF Author: Wilfredo Lopez
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 176

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Drosophila Melanogaster Nora Virus Virus-like Particle

Drosophila Melanogaster Nora Virus Virus-like Particle PDF Author: Kellie D. Licking-Murray
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 166

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Nora Virus as a Model to Study Persistent Infections in Drosophila Melanogaster

Nora Virus as a Model to Study Persistent Infections in Drosophila Melanogaster PDF Author: Mazen Habayeb
Publisher:
ISBN: 9789172647817
Category :
Languages : en
Pages : 39

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Drosophila melanogaster

Drosophila melanogaster PDF Author: Farzana Khan Perveen
Publisher: BoD – Books on Demand
ISBN: 9535138537
Category : Technology & Engineering
Languages : en
Pages : 270

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Book Description
This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.

Using Drosophila Melanogaster as a Model for Viral Infection

Using Drosophila Melanogaster as a Model for Viral Infection PDF Author: Brennen Lee
Publisher:
ISBN:
Category :
Languages : en
Pages : 86

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Genetic Analyses of RNA Silencing as Innate Immunity Against Viruses in Drosophila Melanogaster

Genetic Analyses of RNA Silencing as Innate Immunity Against Viruses in Drosophila Melanogaster PDF Author: Xiaohong Wang
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 382

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Immunity in Insects

Immunity in Insects PDF Author: Federica Sandrelli
Publisher:
ISBN: 9781071602591
Category : Entomology
Languages : en
Pages : 246

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Book Description
This volume details methods and protocols necessary to further the study of insect immunity. Chapters guide readers through up-to-date genomic and transcriptomic approaches, insect samples for proteomic analysis, hemocytes in Drosophila, cellular response in Lepidoptera, insect AMPs, manipulate the composition of mosquito microbiota, viral infections in insects, infections by entomopathogenic nematodes, immune response following oral infections, and protocols to to monitor the effect of septic infections with human pathogens using B. mori as a model. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Immunity in Insects aims to ensure successful results in the further study of this vital field.Incl .

Regulation and Function of the Virus Induced Gene Vago in Drosophila

Regulation and Function of the Virus Induced Gene Vago in Drosophila PDF Author: Safia Deddouche
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
Viral infections continue to be a major cause of morbidity and mortality world-wide. In particular, the past three decades have witnessed the onset of some 25 new viral diseases. Moreover recent outbreaks such as Chikungunya fever in La Réunion demonstrate the enormous public health problem associated with arthropod-borne virus infections. At this stage, our understanding of how the vector responds to virus infection is very limited. The goal of my PhD studies was to use Drosophila melanogaster as a model to study the host response of insects to virus infection. In flies like in mammals, viral infection triggers the expression of a large number of genes. I have provided genetic evidence that the inducible gene Vago limits viral replication. This was the first demonstration that an inducible molecule controls viral replication in drosophila. Interestingly, I have shown that Vago induction is dependant of the Dicer-2 molecule. I also note that Dicer-2 belongs to the same DEXD/H-box helicase family as RIG-I like receptors, which sense viral infection and mediate interferon induction in mammals. I posit that this family represents an evolutionary conserved set of sensors, which detect viral nucleic acids and direct antiviral responses. My work points out that the well known RNaseIII enzyme Dicer-2 plays a dual role during infection: (i) a direct role counteracting viral replication by cutting viral RNA and (ii) a sensing role that triggers antiviral gene expression in Drosophila.

Immunopathology

Immunopathology PDF Author:
Publisher: Academic Press
ISBN: 0128215895
Category : Medical
Languages : en
Pages : 430

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Book Description
Immunopathology, Volume 107 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Viral Immunopathology will cover how the immune system, innate or adaptive, is often at the root of viral pathogenesis. This is true in diverse host systems including vertebrates, plants and insects. This volume will present the latest findings in this interesting and important area of research, and will include human, plant, fish, and insect viruses. Different kingdoms have evolved very diverse immune responses to virus infection but the common theme – namely, that effects of viruses on host immune systems can condition the induction of viral disease – will unify this concept across kingdoms. - The immune system is often responsible for virus pathology - Plants, animals and insects all mount immune responses to virus infection that can increase pathology - Both innate and adaptive immune responses can result in immunopathology