Neutrophil Death Regulation in Critical Illness

Neutrophil Death Regulation in Critical Illness PDF Author: Jia-feng Wang
Publisher: Frontiers Media SA
ISBN: 2832520413
Category : Medical
Languages : en
Pages : 150

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Book Description

Neutrophil Death Regulation in Critical Illness

Neutrophil Death Regulation in Critical Illness PDF Author: Jia-feng Wang
Publisher: Frontiers Media SA
ISBN: 2832520413
Category : Medical
Languages : en
Pages : 150

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Book Description


The Neutrophil

The Neutrophil PDF Author: Jon S. Abramson
Publisher: Oxford University Press, USA
ISBN:
Category : Art
Languages : en
Pages : 348

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Book Description
The third book in the group devoted to the "natural" immune system, this volume provides the ideal detailed, up-to-date overview of neutrophil function. Distilling new information alongside observations of the past, the book focuses on some of the most critical developments in currentneutrophil research. Specific examples of diseases resulting from neutrophil dysfunction and deficiency are brought to life by clinical case studies. An essential source of current research into this exciting field, this volume will be invaluable for advanced students and researchers in immunology,cell biology, and medicine.

Vitamin C

Vitamin C PDF Author: Qi Chen
Publisher: CRC Press
ISBN: 0429807813
Category : Medical
Languages : en
Pages : 269

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Book Description
Vitamin C holds a unique place in scientific and cultural history. In this book, a group of leading scientific researchers describe new insights into the myriad ways vitamin C is employed during normal physiological functioning. In addition, the text provides an extensive overview of the following: the rationale for utilizing vitamin C in the clinic, updates on recent uses of vitamin C in cancer treatment through high-dose intravenous therapies, the role vitamin C plays in the treatment of sepsis and infectious disease, management of the ways vitamin C can improve stem cell differentiation, as well as vitamin C use in other important health situations. Features Includes chapters from a team of leading international scholars Reviews the history and recent research on the functions, benefits, and uses of vitamin C Focuses special attention on the way vitamin C can be used in the treatment of cancers Discusses how vitamin C can be employed against infectious disease

Brain Disorders in Critical Illness

Brain Disorders in Critical Illness PDF Author: Robert D. Stevens
Publisher: Cambridge University Press
ISBN: 1107434424
Category : Medical
Languages : en
Pages : 457

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Book Description
Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

NETosis

NETosis PDF Author: Geeta Rai
Publisher: Academic Press
ISBN: 0128163798
Category : Medical
Languages : en
Pages : 202

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Book Description
NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved. - Presents an up-to-date and detailed analysis of NETosis - Brings together critical findings on NETosis as a comparatively novel immune mechanism - Focuses on the clinical aspects of NETosis that lead to drug development - Covers the topic with a cogency and passion that is based on years of scientific research

Mechanisms of Organ Dysfunction in Critical Illness

Mechanisms of Organ Dysfunction in Critical Illness PDF Author: Timothy W. Evans
Publisher: Springer Science & Business Media
ISBN: 3642561071
Category : Medical
Languages : en
Pages : 434

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Book Description
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ dysfunction under these conditions. Nevertheless, efforts by both clinical and laboratory scientists are leading to new knowledge in this area. The chapters in this volume provide a state-of-the-art overview of many aspects of the pathophysiology of organ dysfunction in critical illness.

Intensive Care Medicine

Intensive Care Medicine PDF Author: Jean-Louis Vincent
Publisher: Springer Science & Business Media
ISBN: 0387773835
Category : Medical
Languages : en
Pages : 913

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Book Description
Intensive Care Medicine compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Yearbook of Intensive Care and Emergency Medicine 2008

Yearbook of Intensive Care and Emergency Medicine 2008 PDF Author: Jean-Louis Vincent
Publisher: Springer Science & Business Media
ISBN: 3540772901
Category : Medical
Languages : en
Pages : 913

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Book Description
The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

NLRP3 Inflammasome: Regulatory Mechanisms, Role in Health and Disease and Therapeutic Potential

NLRP3 Inflammasome: Regulatory Mechanisms, Role in Health and Disease and Therapeutic Potential PDF Author: Kuo-Feng Hua
Publisher: Frontiers Media SA
ISBN: 2889716023
Category : Medical
Languages : en
Pages : 376

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Book Description


Apoptosis and Beyond

Apoptosis and Beyond PDF Author: James A. Radosevich
Publisher: John Wiley & Sons
ISBN: 1119432359
Category : Science
Languages : en
Pages : 768

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Book Description
These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.