Neurobiology of Hyperthermia

Neurobiology of Hyperthermia PDF Author: Hari Shanker Sharma
Publisher: Elsevier
ISBN: 0080549993
Category : Science
Languages : en
Pages : 610

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Book Description
The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1). These chapters are written in review style and embedded with the author’s new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. Describes the importance of brain temperature and hyperthermia in disease processes Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers

Neurobiology of Hyperthermia

Neurobiology of Hyperthermia PDF Author: Hari Shanker Sharma
Publisher: Elsevier
ISBN: 0080549993
Category : Science
Languages : en
Pages : 610

Get Book

Book Description
The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1). These chapters are written in review style and embedded with the author’s new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. Describes the importance of brain temperature and hyperthermia in disease processes Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers

Brain Function in Hot Environment

Brain Function in Hot Environment PDF Author: Hari Shanker Sharma
Publisher: Elsevier Science Limited
ISBN: 9780444823779
Category : Science
Languages : en
Pages : 516

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Book Description
Hardbound. Although problems relating to hyperthermia and heat stroke are well known since biblical times, until now the influence of heat or hyperthermia on the central nervous system has not been well documented. This book is the first to describe in detail the influences of hyperthermia on the CNS using the modern technology which has developed in the last 50 years in neuroscience. Hyperthermia is a common feature during fever, radiotherapy of tumours and exercise in hot environment. Statistically, hyperthermia and/or heat stroke is currently recognised as the third largest killer in America after head and spinal trauma and heart failure. However, studies on the mechanisms of heat-induced death or damage to the CNS are still lacking. This book aims to define the probable mechanisms of brain damage in hyperthermia which could be responsible for death of victims. Rational therapeutic measures based on the experimental findings are also described.The m

The Mystery of Yawning in Physiology and Disease

The Mystery of Yawning in Physiology and Disease PDF Author: Olivier Walusinski
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805594046
Category : Medical
Languages : en
Pages : 174

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Book Description
Yawning is a stereotyped phylogenetically ancient phenomenon that occurs in almost all vertebrates. As an emotional behavior and an expressive movement, yawning has many consequences; nevertheless, it has so far been poorly addressed in medical research and practice. Bringing together the latest research from many fields, this volume integrates current insights within embryology, ethology, neurophysiology, psychology, fMRI and pathology. The phylogenetic and ontogenetic aspects of yawning offer an interesting perspective on human development, and its occurrence in neurological diseases - an area explored by only a few investigators - may provide useful clinical information. This book will make valuable and fascinating reading to neurologists, sleep specialists, psychologists, ethologists and pharmacologists, as well as to anybody interested in uncovering the mystery of yawning.

Indwelling Neural Implants

Indwelling Neural Implants PDF Author: William M. Reichert
Publisher: CRC Press
ISBN: 1420009303
Category : Medical
Languages : en
Pages : 300

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Book Description
Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel

Thermoregulation Part I

Thermoregulation Part I PDF Author:
Publisher: Elsevier
ISBN: 0444639136
Category : Medical
Languages : en
Pages : 496

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Book Description
Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Oxford Textbook of Critical Care

Oxford Textbook of Critical Care PDF Author: Webb
Publisher: Oxford University Press
ISBN: 0198855435
Category : Medical
Languages : en
Pages : 1961

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Book Description
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Intracranial Pressure and Neuromonitoring XVII

Intracranial Pressure and Neuromonitoring XVII PDF Author: Bart Depreitere
Publisher: Springer Nature
ISBN: 303059436X
Category : Medical
Languages : en
Pages : 372

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Book Description
This book gathers the proceedings of the 17th International Conference on Intracranial Pressure and Neuromonitoring, held in Leuven, Belgium in September 2019. It provides an overview of the current understanding, underlying research and future perspectives concerning pathophysiology, biophysics, monitoring and management in traumatic and non-traumatic acute brain injury, hydrocephalus and spinal cord injury, including cerebrovascular autoregulation impairment in neurological as well as non-neurological diseases. The peer-reviewed contributions were prepared by specialists in neurosurgery, neurointensive care and neuroanesthesiology, as well as prominent experts from the fields of physiology, clinical and biomedical engineering, mathematics and informatics. The book continues the time-honored tradition of publishing key presentations from the ICP Conferences in order to facilitate their dissemination within the clinical and research community.

Blood-Spinal Cord and Brain Barriers in Health and Disease

Blood-Spinal Cord and Brain Barriers in Health and Disease PDF Author: Hari Shanker Sharma
Publisher: Elsevier
ISBN: 0080528228
Category : Science
Languages : en
Pages : 605

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Book Description
Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro

Autonomic Neurology

Autonomic Neurology PDF Author: Eduardo E. Benarroch
Publisher: Oxford University Press
ISBN: 0199920206
Category : Medical
Languages : en
Pages : 512

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Book Description
The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.

Questions for the Final FFICM Structured Oral Examination

Questions for the Final FFICM Structured Oral Examination PDF Author: Kate Flavin
Publisher: Cambridge University Press
ISBN: 1108245854
Category : Medical
Languages : en
Pages : 560

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Book Description
This is the first book developed specifically for the Final FFICM structured oral examination. It is written by two senior trainees who have recently passed the exam and is edited by a consultant intensivist with a special interest in education. The book is designed in the style of the SOE, and provides model answers which include summaries of the relevant evidence to guide trainees in their preparation for the exam. The 91 topics and questions therein are drawn from previous exam sittings, and are expanded further to ensure each topic is covered in detail. This text is a valuable revision aid to those studying for the Final FFICM, and will also prove useful to trainees revising for the Final FRCA, as it covers popular ICM topics that often come up in the anaesthetic fellowship exams.