Neurobiology of Cerebrospinal Fluid 1 PDF Download
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Author: James H. Wood
Publisher: Springer Science & Business Media
ISBN: 1468410393
Category : Science
Languages : en
Pages : 771
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Book Description
Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu lation and in elimination of possible sources of error.
Author: James H. Wood
Publisher:
ISBN: 9781468410402
Category :
Languages : en
Pages : 800
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Book Description
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0128025964
Category : Medical
Languages : en
Pages : 778
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Book Description
Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment
Author: James H. Wood
Publisher:
ISBN:
Category : Central nervous sytem
Languages : en
Pages : 0
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Book Description
Author: Wei Zheng
Publisher: CRC Press
ISBN: 9781420023404
Category : Medical
Languages : en
Pages : 668
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Book Description
Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.
Author: Lennart Heimer
Publisher: Springer Science & Business Media
ISBN: 1468401505
Category : Medical
Languages : en
Pages : 396
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Book Description
This book was written to serve both as a guide for the dissection of the human brain and as an illustrated compendium of the functional anatomy of the brain and spinal cord. In this sense, the book represents an updated and expanded version of the book The Human Brain and Spinal Cord written by the author and published in Swedish by Scandinavian University Books in 1961. The complicated anatomy of the brain can often be more easily appreciated and understood in relation to its development. Some insight about the coverings of the brain will also make the brain dissections more meaningful. Introductory chapters on these subjects constitute Part I of the book. Part 2 is composed of the dissection guide, in which text and illustrations are juxtaposed as much as possible in order to facilitate the use of the book in the dissection room. The method of dissection is similar to dissection proce dures used in many medical schools throughout the world, and variations of the technique have been published by several authors including Ivar Broman in the "Manniskohjarnan" (The Human Brain) published by Gleerups F6rlag, Lund, 1926, and Laszlo Komaromy in "Dissection of the Brain," published by Akademiai Kiado, Budapest, 1947. The great popularity of the CT scanner justifies an extra laboratory session for the comparison of nearly horizontal brain sections with matching CT scans.
Author: Charles R. Noback
Publisher: Springer Science & Business Media
ISBN: 9781588290403
Category : Medical
Languages : en
Pages : 500
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Book Description
In this work, the authors integrate three major basic themes of neuroscience to serve as an introduction and review of the subject.
Author: Enrique Santamaría
Publisher: Humana
ISBN: 9781493997084
Category : Medical
Languages : en
Pages : 557
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Book Description
This volume focuses on protein analysis, including a wide range of the use of mass spectrometry and other protein methods within neurobiological disciplines. Chapters cover topics such as cerebrospinal fluid (CSF) processing and biobanking; label-free quantitative proteomics; SWATH; top-down proteomics; and experimental strategies based on other –omics applied to CSF metabolome, lipidome, and microRNAome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols is a valuable resource for graduate students and post-doctoral fellows interested in learning more about CSF proteotyping. It is also useful to established researchers seeking further insight into this growing field.
Author: E. E. Hewer
Publisher: Elsevier
ISBN: 1483195198
Category : Social Science
Languages : en
Pages : 181
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Book Description
An Introduction to the Study of the Nervous System covers topics about the minute structure and functions of the nervous system. The book discusses the minute and gross anatomy of the various parts of the nervous system; the degenerative and regenerative changes following section of the nerves; and the descending and ascending tracts of the spinal cord. The text then describes the cerebellar connections; the deep connections of the cranial nerves; and the microscopic structure of the cortex of the cerebellum and of the cerebrum. The distribution, source, circulation and absorption, pressure, and normal composition of the cerebrospinal fluid and the parts and functions of the autonomic nervous system are also considered. The book further tackles the normal physiology of the sensory and motor paths; the results of interference with the general sensory path at various levels; and the visual path and interference therewith. The text also discusses the cochlear and olfactory paths and the interference therewith and the levels of integration and mechanism of coordinated muscular movement. Students taking courses related to neurology will find the book useful.
Author: P. Michael Conn
Publisher: Springer Science & Business Media
ISBN: 1592593712
Category : Medical
Languages : en
Pages : 707
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Book Description
to it. Once the manuscripts were in hand, it was the The preface to the first edition of Neuroscience in Medicine began with a simple statement: “Neuro- editor’s job to make the writing uniform, remove science is a fascinating discipline.” The interest that duplicative materials except where essential for ease of understanding, and incorporate additional provoked the preparation of a second edition means that statement still rings true. The challenge remained critical material. Neuroscience in Medicine is designed to reveal the to define the core material. I have attempted to restrict certain peripheral topics—the generalities basic science underlying disease and treatments for of biosynthesis and gene expression, for example— neural disorders. Though the chapters are intended to interdigitate, each chapter can be read as a stand in order to allow the remaining topics to include new material and, in some cases, to showcase developing alone—that is, each contains a complete discussion of the topic. areas—neuroimmunology, for example—in the hope that this will pique the interests of the reader and I am pleased that the “Clinical Correlations,” a keep the volume fresh. popular feature of the first edition, are again included. We have also been aided in our task by the art and As in the first edition of Neuroscience in Me- cine, the authors are selected from leaders in editorial staff at Humana, whose help I gratefully acknowledge.
Author: Hugh Davson
Publisher: CRC Press
ISBN: 9780849344725
Category : Science
Languages : en
Pages : 832
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Book Description
This text/reference uses 574 figures and illustrations to help explain the relationships between blood and the cerebrospinal fluid (CSF) and central nervous system (CNS). The authors focus on the interaction of these fluids and the relative importance of the transport mechanisms of hormones from blood to nervous tissue. Carrier-mediated transport of many neuroactive peptides is discussed. Special aspects of the blood-brain barrier are covered in detail. An entire chapter is devoted to the comparative physiology of the CSF and the brain barriers. Physiologists in all fields will have an interest in the updated theories covered in this book.
