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Author:
Publisher: Academic Press
ISBN: 0128161787
Category : Science
Languages : en
Pages : 452
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Book Description
Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology
Author:
Publisher: Academic Press
ISBN: 0128161787
Category : Science
Languages : en
Pages : 452
Get Book Here
Book Description
Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology
Author: Donald L. Riddle
Publisher: Firefly Books
ISBN: 9780879695323
Category : Medical
Languages : en
Pages : 1252
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Book Description
Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309070864
Category : Nature
Languages : en
Pages : 348
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Book Description
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author: Itamar Glazer
Publisher: CABI
ISBN: 1789248795
Category : Science
Languages : en
Pages : 386
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Book Description
Nematodes are small multicellular organisms that have been used as biological models since the 1960s. For example, Caenorhabditis elegans is a free-living nematode worm, about 1mm in length, that lives in temperate soil environments. It is made up of about 1000 cells, and has a short life cycle of only two weeks. It was the first multicellular organism to have its whole genome sequenced. The book summarizes the importance of nematodes as model organisms in the fields of genetics, developmental biology, neurobiology, pharmacology, nutrition, ecology and parasitology. Of interest to a broad audience across a wide spectrum of disciplines, this book is useful for biologists working on comparative studies to investigate biological processes across organisms; medical scientists and pharmacologists for exploration of drugs and medicine (including the use of genome editing to eliminate diseases); ecologists considering nematodes as indicators for environment changes; and parasitologists for host-parasite interactions. Many other researchers can use this book as a benchmark for the broad implications of nematology research on other aspects of science.
Author: William Barry Wood
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 694
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Book Description
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Daiana S. Avila
Publisher:
ISBN: 9781536149463
Category : Science
Languages : en
Pages : 0
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Book Description
Caenorhabditis elegans - An Overview and Emerging Roles in Studying Disease explores different disease models that have been successfully validated in this nematode, either to unravel disease mechanisms or to perform drug screenings. This nonpathogenic organism has helped to firstly identify genetic mechanisms important in cancer (Ras and Bcl oncogene signaling), aging (insulin signaling), and nervous system development (UNC-6/Netrin signaling). Human conditions such as aging/frailty (Chapter One), metabolic syndrome (Chapter Two), neurodegenerative diseases (Chapters Three and Four) and neurodegeneration induced by chemicals (Chapters Three and Five) are recapitulated in C. elegans. The construction of transgenic animals that mimic the diseases, the advances in understanding molecularly these conditions, potential new treatments and limitations of the models are reviewed in these chapters. Notably, the authors that contributed to this book are from different parts of the world due to the widespread use of this nematode in research.
Author: David B. Dusenbery
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 332
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Book Description
V. 1. Behavioral and developmental models.--v. 2. Aging and other model systems.
Author: George O. Poinar Jr.
Publisher: BRILL
ISBN: 9047428668
Category : Science
Languages : en
Pages : 436
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Book Description
Nematodes are one of the most abundant groups of invertebrates on the face of the earth. Their numbers are estimated to range from 1000 per cm2 in the sand-covered hydrogen sulphide ‘black zone’ beneath the ocean floors to 1.2 billion in a single hectare of soil. Estimates for their species diversity range from 100 000 to 10 million. The past history of nematodes is a mystery, since very few fossils have been discovered. This book establishes a solid base in palaeonematology with descriptions of 66 new fossil species and accounts of all previous fossil and subfossil nematodes from sedimentary deposits, coprolites, amber and mummies. It shows how nematode fossils can be used to establish lineages at various locations and time periods in the earth’s history and when nematodes entered into symbiotic and parasitic associations with plants and animals.
