Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: John Wiley & Sons
ISBN: 1119617154
Category : Science
Languages : en
Pages : 628

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Book Description
NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: John Wiley & Sons
ISBN: 1119617154
Category : Science
Languages : en
Pages : 628

Get Book Here

Book Description
NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Blockchain Technology in Healthcare - Concepts, Methodologies, and Applications

Blockchain Technology in Healthcare - Concepts, Methodologies, and Applications PDF Author: Nilayam Kumar Kamila
Publisher: Bentham Science Publishers
ISBN: 9815165208
Category : Computers
Languages : en
Pages : 286

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Book Description
This volume reviews cutting-edge innovations in blockchain technology that are propelling the healthcare industry into a new era of efficiency and security. It brings 14 reviews contributed by experts in blockchain and Web3 technologies into a single volume. Each contribution includes a summary for easy understanding and scientific references for advanced readers. Key Themes: Empowering Decentralized Healthcare: Learn about the future of decentralized healthcare, powered by blockchain, ensuring a seamless and patient-centric experience. Clinical Trials: Discover how blockchain is reshaping clinical trials, offering a glimpse into a future of optimized medical research. Data Security: Uncover the strategic use of blockchain in securing vital clinical trials data, ensuring confidentiality and integrity at every step. Blockchain-based Healthcare delivery: Delve into a comprehensive review of blockchain technology in the health sector, revealing its potential to transform healthcare systems with efficient and precise solutions. Predict, Prevent, and Protect: Understand how blockchain technology serves as a predictive tool, aiding in the prevention and control of the spread of COVID-19. This volume is a must-read for healthcare practitioners and administrators seeking to harness the power of blockchain in medicine and healthcare. It also provides information for researchers and business professionals who want to understand the innovative role of blockchain technology in the healthcare sector.

Phytochemistry, Computational Tools, and Databases in Drug Discovery

Phytochemistry, Computational Tools, and Databases in Drug Discovery PDF Author: Chukwuebuka Egbuna
Publisher: Elsevier
ISBN: 0323907164
Category : Science
Languages : en
Pages : 494

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Book Description
Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants. Various tools and databases for virtual screening and characterization of plant bioactive compounds and their subsequent predictions on biological targets for the discovery of new drugs against specific diseases are presented, along with computational tools for the prediction of the toxic effects of phytochemicals on living systems. The book also provides in-depth insight on the applications of these computational tools as well as the databases that describe the interactions of phytochemicals with diseases along with predictions for druggable bioactive compounds. Useful for drug developers, medicinal chemists, toxicologists, phytochemists, plant biochemists and analytical chemists, this book clearly presents the various computational techniques, tools and databases for phytochemical research. - Provides the various databases, methods and procedures for computational drug discovery in plants - Includes insights into the predictors for properties of phytochemicals against different diseases - Discusses the applications of computational tools and their databases

Sensing and Artificial Intelligence Solutions for Food Manufacturing

Sensing and Artificial Intelligence Solutions for Food Manufacturing PDF Author: Daniel Hefft
Publisher: CRC Press
ISBN: 1000844498
Category : Computers
Languages : en
Pages : 194

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Book Description
This book gives readers a practical introduction into machine learning and sensing techniques, their design and ultimately specific applications that could improve food production. It shows how these sensing and computing systems are suitable for process implementation in food factories. This book starts by giving the reader an overview of the historic structures of food manufacturing standards and how they defined today’s manufacturing. It is followed by a topical introduction for professionals in the food industries in topics such as AI, machine learning, and neural networks. It also includes an explanation of the different sensor systems and their basic principles. It shows how these sensing and computing systems are suitable for process implementation in food factories and what types of sensing systems have already been proven to deliver benefit to the food manufacturing industries. The authors also discuss issues around food safety, labelling, and traceability and how sensing and AI can help to resolve issues. They also use case studies and specific examples that can show the benefit of such technologies compared to current approaches. This book is a practical introduction and handbook for students, food engineers, technologists and process engineers on the benefits and challenges around modern manufacturing systems following Industry 4.0 approaches.

Health Technologies and Informatics

Health Technologies and Informatics PDF Author: Charles Oluwaseun Adetunji
Publisher: CRC Press
ISBN: 1040270255
Category : Technology & Engineering
Languages : en
Pages : 258

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Book Description
Health Technologies and Informatics: Research and Developments provides a comprehensive overview of mobile health applications, biodata management and analytics, medical imaging, personalized and public health systems, and biosignal processing. With a focus on medical informatics, which has been identified as a necessity relating to health challenges relevant to the current pandemic, this book highlights engineering applications and methodologies involved in data evaluations. Detailed information is provided on diseases which could be monitored and necessary intervention for the treatment of these diseases or medical conditions. Features: Provides recent advances on research and developments in the field of biomedical and health informatics Introduces topics such as mobile messaging, objectified information exchange, SmartCare, IoT-driven healthcare, cybersecurity issues, AI-enhanced healthcare, and so forth Covers novel engineering applications and methodologies involved in the pertinent data evaluations Includes dedicated chapters on machine learning in management and mitigation of COVID-19 Explores the role of extended reality in health care including virtual, augmented, and mixed reality This book is aimed at researchers and graduate students in biomedical and computer engineering.

Functional Foods and Nutraceuticals

Functional Foods and Nutraceuticals PDF Author: Chukwuebuka Egbuna
Publisher: Springer Nature
ISBN: 3030423190
Category : Technology & Engineering
Languages : en
Pages : 644

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Book Description
Functional foods and nutraceuticals are food products that naturally offer or have been modified to offer additional health benefits beyond basic nutrition. As such products have surged in popularity in recent years, it is crucial that researchers and manufacturers understand the concepts underpinning functional foods and the opportunity they represent to improve human health, reduce healthcare costs, and support economic development worldwide. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations presents a guide to functional foods from experienced professionals in key institutions around the world. The text provides background information on the health benefits, bioavailability, and safety measurements of functional foods and nutraceuticals. Subsequent chapters detail the bioactive components in functional foods responsible for these health benefits, as well as the different formulations of these products and recent innovations spurred by consumer demands. Authors emphasize product development for increased marketability, taking into account safety issues associated with functional food adulteration and solutions to be found in GMP adherence. Various food preservation methods aimed at enhancing the quality and shelf life of functional food are also highlighted. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations is the first of its kind, designed to be useful to students, teachers, nutritionists, food scientists, food technologists and public health regulators alike.

Tissue Culture Techniques and Medicinal Plants

Tissue Culture Techniques and Medicinal Plants PDF Author: Azamal Husen
Publisher: CRC Press
ISBN: 1040227406
Category : Science
Languages : en
Pages : 472

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Book Description
Nature is the most potent source of cure and care. With the advent of the ‘herbal renaissance,’ the dependence on medicinal plants has increased in all spheres ranging from their use as raw material for medicinal, nutraceutical, cosmetic preparations, and food. The tissue culture technique has proven to be extremely advantageous not only for large-scale propagation of medicinal plants in a limited space and time, but also for conservation, storage for prolonged use, genetic improvement, and metabolite production. This book describes in detail the different methods of plant tissue culture that have been employed for the mass production of medicinal plants. The chapters on methods of organogenesis, embryogenesis, haploid plant production, virus-free medicinal plant production, and so forth will be of interest to a wide range of readers. Dedicated chapters on the tissue culture of high-altitude medicinal plants, cannabis and so on are some of the book's highlights. The book also discusses the implementation of advanced biotechnological interventions such as the production of phytochemicals, cryopreservation, nanotechnology, and bioinformatics in medicinal plant studies. With contributions from world-leading specialists in plant tissue culture, the knowledge presented in this book will aid in the translation of plant tissue culture techniques for the production and improvement of medicinal plants. The information presented has the potential to be utilized for commercial production and formulations. Key features: Comprehensive guide for tissue culture systems as potential methods for the production of clones, new varieties, improved germplasms, haploids, and in vitro preservation of medicinal plants Elaborates on standardization of in vitro systems for propagation and transplantation of important medicinal plants and enhanced secondary metabolite production Enriches the understanding of advanced technologies like cryopreservation, bioinformatics, and nanotechnology in medicinal plants tissue culture

Recent Advances in Environmental Science from the Euro-Mediterranean and Surrounding Regions (4th Edition)

Recent Advances in Environmental Science from the Euro-Mediterranean and Surrounding Regions (4th Edition) PDF Author: Mohamed Ksibi
Publisher: Springer Nature
ISBN: 3031519043
Category :
Languages : en
Pages : 1050

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Book Description


Medicinal Plants: Biodiversity, Biotechnology and Conservation

Medicinal Plants: Biodiversity, Biotechnology and Conservation PDF Author: Sumita Jha
Publisher: Springer Nature
ISBN: 9811999368
Category : Science
Languages : en
Pages : 906

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Book Description
This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases PDF Author: Goutam Brahmachari
Publisher: Elsevier
ISBN: 0128157240
Category : Science
Languages : en
Pages : 461

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Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases