Naturally Occurring Benzodiazepines, Endozepines, and their Receptors

Naturally Occurring Benzodiazepines, Endozepines, and their Receptors PDF Author: Robert B. Raffa
Publisher: CRC Press
ISBN: 1000421279
Category : Medical
Languages : en
Pages : 216

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Book Description
Understanding and addressing the current opioid crisis requires knowledge of endogenous opioids (endorphins and enkephalins), but there is now evidence for a benzodiazepine crisis. Are there endogenous benzodiazepine-like substances—and what do they do? How do they affect antianxiety drugs and their adverse effects? Do they explain enigmatic prolonged benzodiazepine withdrawal syndrome? This book raises important questions about the clinical consequences of ignoring the existence of or understanding the potential influence of endogenous benzodiazepines on the therapeutic effect of benzodiazepines, their adverse effects, and the problems of withdrawal from them and other benzodiazepine receptor agonists. FEATURES Discusses endogenous benzodiazepine-like substances—what do they do, and do they affect antianxiety drugs and their adverse effects? Presents information on enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites, both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology, pathology, and pharmacology of the compounds acting at the BDZ binding sites Dr. Raffa is Adjunct Professor at the University of Arizona College of Pharmacy and Professor Emeritus at Temple University School of Pharmacy. He has co-authored or edited several books on pharmacology and thermodynamics, is a co-editor of two journals, is a past president of the Mid-Atlantic Pharmacology Society, and is the recipient of research and teaching awards. Dr. Amantea is Associate Professor of Pharmacology at the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria (Italy), where she is the leader of the Stroke Research Unit at the Section of Preclinical and Translational Pharmacology operating in the frame of the Italian Stroke Organization (ISO) Basic Science. She is a member of the Editorial Board and the Guest Editor of the 2016 Neuroscience section of Current Opinion in Pharmacology (Elsevier), and the founder and the editor of the CRC Press Frontiers in Neurotherapeutics series.

Naturally Occurring Benzodiazepines

Naturally Occurring Benzodiazepines PDF Author: Ivan Izquierdo
Publisher: CRC Press
ISBN: 9780130154880
Category : Medical
Languages : en
Pages : 146

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Book Description
An exploration of benzodiazepines (BZDs), including the widely-used drug Valium, which have been in wide circulation in clinical practice since the 1960s as sedatives, antidepressants, hypnotics and anticonvulsants. It reveals research results with naturally-occurring BZDs in plants and animals.

The Ashton Manual (Revised)

The Ashton Manual (Revised) PDF Author: Prof Ashton
Publisher: Blurb
ISBN:
Category : Education
Languages : en
Pages : 0

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Book Description
This publication presents insights into the impacts of benzodiazepines on both the mind and body, elucidating the mechanisms through which these effects manifest. It offers comprehensive guidance on safely discontinuing usage following extended periods, furnishing tailored tapering plans for various benzodiazepines. The text delves into withdrawal symptoms, both immediate and prolonged, elucidating their underlying causes and strategies for managing them. Ultimately, the overarching message underscores the potential for successful withdrawal among most long-term benzodiazepine users, leading to enhanced well-being and contentment.

Seminars in Clinical Psychopharmacology

Seminars in Clinical Psychopharmacology PDF Author: Peter M. Haddad
Publisher:
ISBN: 9781911623465
Category :
Languages : en
Pages :

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Book Description
"The 2nd edition of this book was edited by David King and published in 2004. Since then there have been major advances in psychopharmacology in terms of new medications coming to the market, increased understanding of the mechanisms of drug action and new data on the efficacy, tolerability, safety and clinical effectiveness of a range of medications. Partly as a result, clinical guidelines for many psychiatric disorders have altered. As such, a new edition of this textbook was essential and we were delighted when the College approached us to edit the 3rd edition. This was a major endeavor that was only possible with the commitment and expertise of the authors"--

Understanding the Behavioral and Medical Impact of Long COVID

Understanding the Behavioral and Medical Impact of Long COVID PDF Author: Leonard A. Jason
Publisher: Taylor & Francis
ISBN: 1000874737
Category : Health & Fitness
Languages : en
Pages : 298

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Book Description
Understanding the Behavioral and Medical Impact of Long COVID serves to expand the research around the illness in order to enable health care researchers and practitioners to address the questions that are imperative to individuals suffering from this condition. Through its multi-faceted approach, the book puts forth a maturation of research and interventions that are theoretically sound, empirically valid, innovative, and creative in the Long COVID area. As a scholarly and scientific compilation of Long COVID symptoms and related disorders, this book offers unparalleled insight into the critical developments across medical areas treating this illness. It helps to fill the space that the pandemic had created for knowledge of the condition, and contributes to the emerging emphasis on translational research blending the social sciences and biological fields. By putting forth the most optimal medical care practices in the treatment of complex Long COVID symptoms, this practical anthology will serve as a guide for practicing clinicians in assessment as well as treatment. It will also benefit researchers aiming to gain more understanding of Long COVID through its discussion around the critical developments in other medical areas treating the condition, and paves the way for the collaboration and future research needed to best support the global effort to mitigate the effects of this illness. This book will be essential reading for academics, practitioners, and researchers. It will appeal to individuals engaging with the fields of medicine, public policy, psychology, and for researchers looking to gain clarity about our current understanding of Long COVID. It will further be of interest to public/government agencies, nonprofit organizations, and the general public wanting to gain more information about these ambiguous and evasive symptoms.

Translocator Protein (TSPO)

Translocator Protein (TSPO) PDF Author: Giovanni Natile
Publisher: MDPI
ISBN: 3038427578
Category : Science
Languages : en
Pages : 177

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Book Description
This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS

Sleep Disorders Medicine

Sleep Disorders Medicine PDF Author: Sudhansu Chokroverty
Publisher: Saunders
ISBN:
Category : Health & Fitness
Languages : en
Pages : 710

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Book Description
Dr. Sudhansu Chokroverty-a world-recognized expert in sleep medicine-presents the third edition of Sleep Disorders Medicine for the latest developments in this rapidly expanding specialty, with coverage of neuroscience and clinical application. In addition to summarizing basic science and important technological aspects of diagnosis and treatment, this edition presents new chapters-on sleep and memory consolidation, neuroimaging, and more-in a color layout that makes it easy to access the latest advances in the field. The text's manageable size and logical, multi-disciplinary approach make it the right choice for newcomers and experienced clinicians alike. Covers all aspects of sleep medicine in a practical, logical format divided into three sections: the basic science of sleep physiology, neuroanatomy, and biochemistry; the technical methods of recording; and a clinical approach to patients with sleep complaints. Represents the breadth of knowledge across disciplines through the contributions of 50 prominent names in the field of sleep medicine. Provides a multidisciplinary approach to the diagnosis and management of sleep disorders with coverage of related fields such as pulmonology, otolaryngology, and psychiatry. Includes a Glossary of Terms adapted from the American Sleep Disorders Association for quick reference to the sleep terminology used throughout the text. Offers online access to the full text through Expert Consult functionality for convenient reference. Demonstrates how recent basic science advances affect clinical medicine through new chapters on Sleep Deprivation and Sleepiness; Sleep and Memory Consolidation; Neuroimaging in Sleep and Sleep Disorders; Nutrition and Sleep; Nature and Treatment of Insomnia; Evolution of Sleep from Birth through Adolescence; Sleep-Disordered Breathing in Children and Women's Sleep. Improves on the clarity and consistency of the text with a new, completely redrawn art program, including full-color illustrations in the clinical section that enhances diagnostic material. Presents the material in an even more readable and user-friendly two-color design and page layout.

Flavonoids

Flavonoids PDF Author: José Justino
Publisher: BoD – Books on Demand
ISBN: 953513423X
Category : Science
Languages : en
Pages : 486

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Book Description
Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.

Fundamentals of Psychopharmacology

Fundamentals of Psychopharmacology PDF Author: Brian E. Leonard
Publisher: John Wiley & Sons
ISBN: 0470842377
Category : Medical
Languages : en
Pages : 536

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Book Description
Treatment with drugs is fundamental to modern therapy of psychiatric disorders. The number of disorders responsive to drug treatment is increasing, reflecting the extensive synthesis of novel compounds and the greater understanding of the aetiology of the disorders. This third edition provides new and updated material, including an additional chapter on clinical trials and their importance in assessing the efficacy and safety of psychotropic drugs. As molecular biology and imaging techniques are of increasing importance to basic and clinical neuroscience, these areas have also been extended to illustrate their relevance to our understanding of psychopharmacology. This book is essential reading for undergraduates in pharmacology and the neurosciences, postgraduate neuropharmacologists, psychiatrists in training and in practice and medical researchers. Reviews of the Second Edition "...this text is eminently readable, well researched, and probably the best of its kind. The book is well worth buying and anyone who claims to know anything about psychopharmacology will be expected to have a heavily annotated copy." Irish Journal of Psychological Medicine "...[this is] a very good book, especially suited to those interested in psychopharmacologic research and psychiatric residency in training." Journal of Chemical Neuroanatomy

The Role of Glia in Neurotoxicity

The Role of Glia in Neurotoxicity PDF Author: Michael Aschner
Publisher: CRC Press
ISBN: 1420039741
Category : Medical
Languages : en
Pages : 477

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Book Description
Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.