Mutations - Episode 1

Mutations - Episode 1 PDF Author: Leo
Publisher: Cinebook
ISBN: 1800449674
Category : Comics & Graphic Novels
Languages : en
Pages : 66

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Book Description
After a global environmental disaster, mankind has rebuilt, but its demons are still there. Greed, arrogance ... Romane Pennac fights those who would abuse nature once again. Volume 1 of 2 of this sequel to Mermaid Project. Two years have passed since the event of Mermaid Project, and Romane and Brahim have paid the price of their courage and integrity. Ignored, even censored, by their superiors, they’re now reduced to taking lousy private eye jobs to earn a living. Meanwhile, though, the same cetaceans whose advanced intelligence the UN had refused to believe in are attacking fishing trawlers ... with rockets! Before long, the authorities ask our two investigators to take their old jobs back ...

Mutations - Episode 1

Mutations - Episode 1 PDF Author: Leo
Publisher: Cinebook
ISBN: 1800449674
Category : Comics & Graphic Novels
Languages : en
Pages : 66

Get Book Here

Book Description
After a global environmental disaster, mankind has rebuilt, but its demons are still there. Greed, arrogance ... Romane Pennac fights those who would abuse nature once again. Volume 1 of 2 of this sequel to Mermaid Project. Two years have passed since the event of Mermaid Project, and Romane and Brahim have paid the price of their courage and integrity. Ignored, even censored, by their superiors, they’re now reduced to taking lousy private eye jobs to earn a living. Meanwhile, though, the same cetaceans whose advanced intelligence the UN had refused to believe in are attacking fishing trawlers ... with rockets! Before long, the authorities ask our two investigators to take their old jobs back ...

Selection

Selection PDF Author: Graham Bell
Publisher: OUP Oxford
ISBN: 0191546895
Category : Science
Languages : en
Pages : 568

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Book Description
This book adopts an experimental approach to understanding the mechanisms of evolution and the nature of evolutionary processes, with examples drawn from microbial, plant and animal systems. It incorporates insights from remarkable recent advances in theoretical modelling, and the fields of molecular genetics and environmental genomics. Adaptation is caused by selection continually winnowing the genetic variation created by mutation. In the last decade, our knowledge of how selection operates on populations in the field and in the laboratory has increased enormously, and the principal aim of this book is to provide an up-to-date account of selection as the principal agent of evolution. In the classical Fisherian model, weak selection acting on many genes of small effect over long periods of time is responsible for driving slow and gradual change. However, it is now clear that adaptation in laboratory populations often involves strong selection acting on a few genes of large effect, while in the wild selection is often strong and highly variable in space and time. Indeed these results are changing our perception of how evolutionary change takes place. This book summarizes our current understanding of the causes and consequences of selection, with an emphasis on quantitative and experimental studies. It includes the latest research into experimental evolution, natural selection in the wild, artificial selection, selfish genetic elements, selection in social contexts, sexual selection, and speciation.

The Basics of Selection

The Basics of Selection PDF Author: Graham Bell
Publisher: Springer Science & Business Media
ISBN: 0412055317
Category : Medical
Languages : en
Pages : 404

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Book Description
Graham Bell, an internationally recognized evolutionary biologist, has written a simple text that avoids mathematical arguments or technical details, while giving a rigorous introduction to the field. The book is organized as a series of short sections, each designed to make a particular point, and illustrated whenever possible by experimental results.

Goldman-Cecil Medicine E-Book

Goldman-Cecil Medicine E-Book PDF Author: Lee Goldman
Publisher: Elsevier Health Sciences
ISBN: 0323322859
Category : Medical
Languages : en
Pages : 4123

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Book Description
Since 1927, Goldman-Cecil Medicine has been the world’s most influential internal medicine resource. In the ground-breaking 25th edition, your original purchase ensures you will be up-to-date without the need for a subscription. Through the new, more powerful Expert Consult eBook platform, this "living text" provides continuous updates that will integrate the latest research, guidelines, and treatments into each chapter, ensuring that the content is as current as the day this edition was first published. Goldman-Cecil Medicine offers definitive, unbiased guidance on the evaluation and management of every medical condition, presented by a veritable "Who's Who" of modern medicine. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this dynamic resource quite simply the fastest and best place to find all of the authoritative, state-of-the-art clinical answers you need. Expert Consult eBook version included with print purchase: Access continuous updates from Editor Lee Goldman, MD, who thoroughly reviews internal medicine and specialty journals, updating online content to reflect the latest guidelines and translating that evidence into treatment. Interactive Q&A section features over 1,500 board-style questions and answers to aid in preparing for certification or recertification exams. Outstanding supplementary tools include figures, tables, videos, heart and lung sounds, treatment and management algorithms, fully integrated references, and thousands of illustrations and full-color photos. Search all of the text, figures, supplementary material, and references from the book on a variety of devices and at no additional cost — Expert Consult access is included with this title! Practical, bulleted, highly templated text with easy-to-use features including flow charts and treatment boxes. New chapters on global health, cancer biology and genetics, and the human microbiome in health and disease keep you on the cutting edge of medicine. Today's most current evidence-based medicine guidelines help you form a definitive diagnosis and create the best treatment plans possible. Focused coverage of the latest developments in biology includes the specifics of current diagnosis, therapy, and medication doses. The reference of choice for every stage of your career! Goldman-Cecil Medicine is an ideal learning tool for residents, physicians, and students as well as a valuable go-to resource for experienced healthcare professionals.

Clinical Immunology,Principles and Practice (Expert Consult - Online and Print),4

Clinical Immunology,Principles and Practice (Expert Consult - Online and Print),4 PDF Author: Thomas A. Fleisher
Publisher: Elsevier Health Sciences
ISBN: 0723436916
Category : Medical
Languages : en
Pages : 1325

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Book Description
Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely current. Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems. A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice. Cutting-edge coverage of the human genome project, immune-modifier drugs, and many other vital updates keeps you at the forefront of your field. A new organization places scientific and clinical material side by side, to simplify your research and highlight the clinical relevance of the topics covered. A multimedia format allows you to find information conveniently, both inside the exceptionally user-friendly book and at the fully searchable companion web site. Regular updates online ensure that you'll always have the latest knowledge at your fingertips. Includes many new and improved illustrations and four color design. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Voltage-Gated Calcium Channels

Voltage-Gated Calcium Channels PDF Author: Gerald Werner Zamponi
Publisher: Springer Science & Business Media
ISBN: 0387275266
Category : Science
Languages : en
Pages : 392

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Book Description
oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar macological targets in the treatment of a variety of disorders, such as epi lepsy, hypertension, and pain. Voltage-gated calcium channels have there fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac tivity, the book delves into a provocative overview of the history of the cal cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat ing, permeation, modulation and interactions with members of the exo- totic machinery—contributed by both established leaders and rising stars in the field.

Bioimaging in Neurodegeneration

Bioimaging in Neurodegeneration PDF Author: Patricia A. Broderick
Publisher: Springer Science & Business Media
ISBN: 1592598889
Category : Medical
Languages : en
Pages : 313

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Book Description
Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.

Cardiac Electrophysiology

Cardiac Electrophysiology PDF Author: Andrea Natale
Publisher: Springer Nature
ISBN: 3030285332
Category : Medical
Languages : en
Pages : 648

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Book Description
While there are many outstanding resources providing in-depth review of electrophysiology topics, this extensively updated book is one of the few case-based books that comprehensively cover clinical electrophysiology, devices and ablation. Case review offers a simple, yet effective way in teaching important concepts, offering insight into both the basic pathophysiology of a problem as well as the clinical reasoning that leads to a solution. As the field of cardiac electrophysiology evolves, the challenge remains to educate new generations of cardiac electrophysiologists with the basics as well as the latest advances in the field. Cardiac Electrophysiology: Clinical Case Review collates the most comprehensive case-based reviews of electrophysiology designed to appeal to all students of the field whether they are fellows, allied professionals or practicing electrophysiologists. The Editors have recruited some of the true experts in the field to contribute cases that they have encountered and summarizing the important learning objectives in a succinct way. Covering clinical electrophysiology, device troubleshooting and analysis as well as intracardiac electrogram analysis and ablation, readers will find the cases useful as a review of electrophysiology or in their day to day interactions with patients.

Swaiman's Pediatric Neurology - E-Book

Swaiman's Pediatric Neurology - E-Book PDF Author: Stephen Ashwal
Publisher: Elsevier Health Sciences
ISBN: 0443111065
Category : Medical
Languages : en
Pages : 1432

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Book Description
For fifty years, experienced clinicians and physicians in training have relied on Swaiman's cornerstone text as their #1 source for authoritative guidance in pediatric neurology. Swaiman's Pediatric Neurology: Principles and Practice, 7th Edition, continues this tradition of excellence under the expert editorial direction of Drs. Stephen Ashwal and Phillip L. Pearl, along with a team of key leaders in the field who serve as associate and section editors in their areas of expertise. Thorough revisions—including new chapters, new videos, new editors, and expanded content—bring you up to date with this dynamic field. - Contains new sections on global child neurology and environment and brain development and a greatly expanded section on neurogenetics, in addition to new chapters on autoimmune epilepsies, immune-mediated movement disorders, and more. - Offers expanded online content, including additional figures, tables, and text, as well as new personal introductory videos by many chapter authors. - Covers new, emerging, or controversial topics such as COVID-19, teleneurology, environment and brain development, immune-mediated disorders of the nervous system, functional neurological disorders in children, nonverbal learning disorders, and the pharmacological and future genetic treatment of neurodevelopmental disabilities. - Provides authoritative coverage of perinatal acquired and congenital disorders, neurodevelopmental disabilities, extensive sections on pediatric epilepsy and movement disorders, nonepileptiform paroxysmal disorders, and disorders of sleep. - Features nearly 3,000 line drawings, photographs, tables, and boxes that highlight the text, clarify key concepts, and make it easy to find information quickly.

Mendelian Inheritance in Man

Mendelian Inheritance in Man PDF Author: Victor A. McKusick
Publisher: JHU Press
ISBN: 9780801857423
Category : Health & Fitness
Languages : en
Pages : 1726

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Book Description
The twelfth edition of this classic reference work includes: - More than 2,000 new entries - A total of more than 9,000 entries - New features and enhancement of the familiar old features - Mapping information on more than 4,000 genes of known function - Information on specific point mutations responsible for more than 700 genetic disorders or neoplasms Mendelian Inheritance in Man (MIM) is a genetic knowledgebase that serves clinical medicine and biomedical research, including the Human Genome Project. It aims to be comprehensive (not only complete, but also collated, integrated, and interpreted), authoritative (not only accurate but also sound in its interpretations and judgements), and timely (not only up-to-date but also historically dimensioned). From a review of the eleventh edition, Reproductive Toxicology: "Even the convenience of computer-based forms of MIM cannot eliminate the need for MIM in book form. The preface provides a wonderful synopsis of human genetics. The information contained in this text serves as a concise review for those with a genetics background." From a review of the tenth edition, New England Journal of Medicine: " Victor McKusick] has been for all these years the shepherd of the development of the field of clinical genetics]. Perhaps his most important pragmatic achievement has been the 10 editions of Mendelian Inheritance in Man, which rapidly became and has remained the principal source of information on inherited diseases for all clinical geneticists. "In addition to the erudite entries in the books, the references given with each description represent a magnificent bibliography of clinical genetics. With McKusick's leadership and continued interest in gene mapping, the book also rep-resents an important compen-dium of the location of genes on specific chromosomes. "The book is a magnificent security blanket for the clinical geneticist and should be in the libraries not only of these specialists, but also of all others who see patients with diseases that have genetic components."