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Author: Giovanni Cugliari
Publisher: GRIN Verlag
ISBN: 365697375X
Category : Medical
Languages : en
Pages : 185
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Book Description
Research Paper (postgraduate) from the year 2015 in the subject Medicine - Other, grade: II Level Master, University of Pavia (Unit of Medical and Genomic Statistics), course: Medical and Genomic Statistics, language: English, abstract: Electroencephalography, commonly called 'EEG', estimates through the application of electrodes, the electrical activity of the brain (which is the sum of the electrical activity of each neuron). In recent years, with the goal of making more reliable the EEG, many researchers have turned their interest in the development of tools, methods and software. This thesis describes some best procedures for the experimental design, data visualization and descriptive or inferential statistical analysis. The application of statistical models to single or multiple subjects study-design are also described, including parametric and non-parametric approaches. Methods for processing multivariate data (PCA, ICA, clustering) were described. Re-sampling methods (bootstrap) using many randomly software-generated samples were also described. The aim of this work is to provide, with statistical concepts and examples, information on the qualitative and quantitative approaches related to the electroencephalographic signals. The work consists into three parts: INTRODUTION TO ELECTROENCEPHALOGRAPHY (GENERAL CHARACTERISTICS); DATA MINING AND STATISTICAL ANALYSIS; EXPERIMENTAL STUDY DESIGNS. The six works included in the section called “EXPERIMENTAL STUDY DESIGNS” analyze EEG alterations in the protocols: Electrocortical activity in dancers and non-dancers listening to different music genre and during imaginative dance motor activity; Electrocortical activity during monosynaptic reflex in athletes; Monitoring of electrocortical activity for evaluation of seasickness; Electrocortical activity in different body positions; Electrocortical activity in athletes and non-athletes during body balance tasks; Electrocortical responses in volunteers with and without specific experience watching movies including the execution of complex motor gestures. In the section called “OTHER INTERESTING THINGS” were included one work that analyze EMG (electromyography) alterations in pathological and healthy subjects in the protocol: Comparison between clinical diagnostic criteria of sleep bruxism and those provided by a validated portable holter. The described procedures can be used for clinical trials, although the studies proposed in this work do not refer to samples from pathological subjects. With its multi-specialist approach, through many theoretical and practical feedback, this work will be useful for specializing in neuroscience, statistics, engineering or physiology.
Author: Giovanni Cugliari
Publisher: GRIN Verlag
ISBN: 365697375X
Category : Medical
Languages : en
Pages : 185
Get Book
Book Description
Research Paper (postgraduate) from the year 2015 in the subject Medicine - Other, grade: II Level Master, University of Pavia (Unit of Medical and Genomic Statistics), course: Medical and Genomic Statistics, language: English, abstract: Electroencephalography, commonly called 'EEG', estimates through the application of electrodes, the electrical activity of the brain (which is the sum of the electrical activity of each neuron). In recent years, with the goal of making more reliable the EEG, many researchers have turned their interest in the development of tools, methods and software. This thesis describes some best procedures for the experimental design, data visualization and descriptive or inferential statistical analysis. The application of statistical models to single or multiple subjects study-design are also described, including parametric and non-parametric approaches. Methods for processing multivariate data (PCA, ICA, clustering) were described. Re-sampling methods (bootstrap) using many randomly software-generated samples were also described. The aim of this work is to provide, with statistical concepts and examples, information on the qualitative and quantitative approaches related to the electroencephalographic signals. The work consists into three parts: INTRODUTION TO ELECTROENCEPHALOGRAPHY (GENERAL CHARACTERISTICS); DATA MINING AND STATISTICAL ANALYSIS; EXPERIMENTAL STUDY DESIGNS. The six works included in the section called “EXPERIMENTAL STUDY DESIGNS” analyze EEG alterations in the protocols: Electrocortical activity in dancers and non-dancers listening to different music genre and during imaginative dance motor activity; Electrocortical activity during monosynaptic reflex in athletes; Monitoring of electrocortical activity for evaluation of seasickness; Electrocortical activity in different body positions; Electrocortical activity in athletes and non-athletes during body balance tasks; Electrocortical responses in volunteers with and without specific experience watching movies including the execution of complex motor gestures. In the section called “OTHER INTERESTING THINGS” were included one work that analyze EMG (electromyography) alterations in pathological and healthy subjects in the protocol: Comparison between clinical diagnostic criteria of sleep bruxism and those provided by a validated portable holter. The described procedures can be used for clinical trials, although the studies proposed in this work do not refer to samples from pathological subjects. With its multi-specialist approach, through many theoretical and practical feedback, this work will be useful for specializing in neuroscience, statistics, engineering or physiology.
Author: Daniel Durstewitz
Publisher: Springer
ISBN: 3319599763
Category : Medical
Languages : en
Pages : 292
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Book Description
This book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanatory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function." Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego “This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. “ Bruno B. Averbeck
Author: Atsushi Kawaguchi
Publisher: CRC Press
ISBN: 9780367752217
Category : Brain
Languages : en
Pages : 0
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Book Description
This book enables us to analyze statistically brain imaging data. It is meant for a wide range of researchers interested in biostatistics, data science, and neuroscience. It is useful to understand the background theory of standard software for neuroimaging data analysis.
Author: Bruce L. Brown
Publisher: John Wiley & Sons
ISBN: 1118131614
Category : Mathematics
Languages : en
Pages : 404
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Book Description
An insightful guide to understanding and visualizing multivariate statistics using SAS®, STATA®, and SPSS® Multivariate Analysis for the Biobehavioral and Social Sciences: A Graphical Approach outlines the essential multivariate methods for understanding data in the social and biobehavioral sciences. Using real-world data and the latest software applications, the book addresses the topic in a comprehensible and hands-on manner, making complex mathematical concepts accessible to readers. The authors promote the importance of clear, well-designed graphics in the scientific process, with visual representations accompanying the presented classical multivariate statistical methods . The book begins with a preparatory review of univariate statistical methods recast in matrix notation, followed by an accessible introduction to matrix algebra. Subsequent chapters explore fundamental multivariate methods and related key concepts, including: Factor analysis and related methods Multivariate graphics Canonical correlation Hotelling's T-squared Multivariate analysis of variance (MANOVA) Multiple regression and the general linear model (GLM) Each topic is introduced with a research-publication case study that demonstrates its real-world value. Next, the question "how do you do that?" is addressed with a complete, yet simplified, demonstration of the mathematics and concepts of the method. Finally, the authors show how the analysis of the data is performed using Stata®, SAS®, and SPSS®. The discussed approaches are also applicable to a wide variety of modern extensions of multivariate methods as well as modern univariate regression methods. Chapters conclude with conceptual questions about the meaning of each method; computational questions that test the reader's ability to carry out the procedures on simple datasets; and data analysis questions for the use of the discussed software packages. Multivariate Analysis for the Biobehavioral and Social Sciences is an excellent book for behavioral, health, and social science courses on multivariate statistics at the graduate level. The book also serves as a valuable reference for professionals and researchers in the social, behavioral, and health sciences who would like to learn more about multivariate analysis and its relevant applications.
Author: Young K. Truong
Publisher: CRC Press
ISBN: 1315356759
Category : Mathematics
Languages : en
Pages : 349
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Book Description
Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein. The book examines current statistical methods for solving emerging problems in neuroscience. These methods have been applied to data involving multichannel neural spike train, spike sorting, blind source separation, functional and effective neural connectivity, spatiotemporal modeling, and multimodal neuroimaging techniques. The author provides an overview of various methods being applied to specific research areas of neuroscience, emphasizing statistical principles and their software. The book includes examples and experimental data so that readers can understand the principles and master the methods. The first part of the book deals with the traditional multivariate time series analysis applied to the context of multichannel spike trains and fMRI using respectively the probability structures or likelihood associated with time-to-fire and discrete Fourier transforms (DFT) of point processes. The second part introduces a relatively new form of statistical spatiotemporal modeling for fMRI and EEG data analysis. In addition to neural scientists and statisticians, anyone wishing to employ intense computing methods to extract important features and information directly from data rather than relying heavily on models built on leading cases such as linear regression or Gaussian processes will find this book extremely helpful.
Author: Atsushi Kawaguchi
Publisher: CRC Press
ISBN: 1000369870
Category : Mathematics
Languages : en
Pages : 214
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Book Description
This book describes methods for statistical brain imaging data analysis from both the perspective of methodology and from the standpoint of application for software implementation in neuroscience research. These include those both commonly used (traditional established) and state of the art methods. The former is easier to do due to the availability of appropriate software. To understand the methods it is necessary to have some mathematical knowledge which is explained in the book with the help of figures and descriptions of the theory behind the software. In addition, the book includes numerical examples to guide readers on the working of existing popular software. The use of mathematics is reduced and simplified for non-experts using established methods, which also helps in avoiding mistakes in application and interpretation. Finally, the book enables the reader to understand and conceptualize the overall flow of brain imaging data analysis, particularly for statisticians and data-scientists unfamiliar with this area. The state of the art method described in the book has a multivariate approach developed by the authors’ team. Since brain imaging data, generally, has a highly correlated and complex structure with large amounts of data, categorized into big data, the multivariate approach can be used as dimension reduction by following the application of statistical methods. The R package for most of the methods described is provided in the book. Understanding the background theory is helpful in implementing the software for original and creative applications and for an unbiased interpretation of the output. The book also explains new methods in a conceptual manner. These methodologies and packages are commonly applied in life science data analysis. Advanced methods to obtain novel insights are introduced, thereby encouraging the development of new methods and applications for research into medicine as a neuroscience.
Author: Nicole Lazar
Publisher: Springer Science & Business Media
ISBN: 0387781919
Category : Medical
Languages : en
Pages : 302
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Book Description
The study of brain function is one of the most fascinating pursuits of m- ern science. Functional neuroimaging is an important component of much of the current research in cognitive, clinical, and social psychology. The exci- ment of studying the brain is recognized in both the popular press and the scienti?c community. In the pages of mainstream publications, including The New York Times and Wired, readers can learn about cutting-edge research into topics such as understanding how customers react to products and - vertisements (“If your brain has a ‘buy button,’ what pushes it?”, The New York Times,October19,2004),howviewersrespondtocampaignads(“Using M. R. I. ’s to see politics on the brain,” The New York Times, April 20, 2004; “This is your brain on Hillary: Political neuroscience hits new low,” Wired, November 12,2007),howmen and womenreactto sexualstimulation (“Brain scans arouse researchers,”Wired, April 19, 2004), distinguishing lies from the truth (“Duped,” The New Yorker, July 2, 2007; “Woman convicted of child abuse hopes fMRI can prove her innocence,” Wired, November 5, 2007), and even what separates “cool” people from “nerds” (“If you secretly like Michael Bolton, we’ll know,” Wired, October 2004). Reports on pathologies such as autism, in which neuroimaging plays a large role, are also common (for - stance, a Time magazine cover story from May 6, 2002, entitled “Inside the world of autism”).
Author: Robert E. Kass
Publisher: Springer
ISBN: 1461496020
Category : Medical
Languages : en
Pages : 663
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Book Description
Continual improvements in data collection and processing have had a huge impact on brain research, producing data sets that are often large and complicated. By emphasizing a few fundamental principles, and a handful of ubiquitous techniques, Analysis of Neural Data provides a unified treatment of analytical methods that have become essential for contemporary researchers. Throughout the book ideas are illustrated with more than 100 examples drawn from the literature, ranging from electrophysiology, to neuroimaging, to behavior. By demonstrating the commonality among various statistical approaches the authors provide the crucial tools for gaining knowledge from diverse types of data. Aimed at experimentalists with only high-school level mathematics, as well as computationally-oriented neuroscientists who have limited familiarity with statistics, Analysis of Neural Data serves as both a self-contained introduction and a reference work.
Author: T. Naes
Publisher: Elsevier
ISBN: 0080537162
Category : Education
Languages : en
Pages : 365
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Book Description
The state-of-the-art of multivariate analysis in sensory science is described in this volume. Both methods for aggregated and individual sensory profiles are discussed. Processes and results are presented in such a way that they can be understood not only by statisticians but also by experienced sensory panel leaders and users of sensory analysis. The techniques presented are focused on examples and interpretation rather than on the technical aspects, with an emphasis on new and important methods which are possibly not so well known to scientists in the field. Important features of the book are discussions on the relationship among the methods with a strong accent on the connection between problems and methods. All procedures presented are described in relation to sensory data and not as completely general statistical techniques. Sensory scientists, applied statisticians, chemometricians, those working in consumer science, food scientists and agronomers will find this book of value.
Author: William D. Penny
Publisher: Elsevier
ISBN: 0080466508
Category : Psychology
Languages : en
Pages : 689
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Book Description
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. An essential reference and companion for users of the SPM software Provides a complete description of the concepts and procedures entailed by the analysis of brain images Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data Stands as a compendium of all the advances in neuroimaging data analysis over the past decade Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes Structured treatment of data analysis issues that links different modalities and models Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible
