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Category :
Languages : en
Pages : 834
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Author:
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ISBN:
Category :
Languages : en
Pages : 834
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Book Description
![Mr. De Witt, from the Committee on Claims, Submitted the Following Report: [To Accompany H. R. 1121.] PDF](https://books.google.com/books/content/images/frontcover/_wKRrUh5CBQC?fife=w80-h100)
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Languages : en
Pages : 2
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![Mr. De Witt, from the Committee on Claims, Submitted the Following Report: [To Accompany H. R. 596.] PDF](https://books.google.com/books/content/images/frontcover/51Vb94qNNi8C?fife=w80-h100)
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Category :
Languages : en
Pages : 2
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![Mr. De Witt, from the Committee on Claims, Submitted the Following Report: [To Accompany S. 758.] PDF](https://books.google.com/books/content/images/frontcover/_rHesxc3TuIC?fife=w80-h100)
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Category :
Languages : en
Pages : 4
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![Mr. De Witt, from the Committee on Claims, Submitted the Following Report: [To Accompany S. 517.] PDF](https://books.google.com/books/content/images/frontcover/Jmb9lfG8vCkC?fife=w80-h100)
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Category :
Languages : en
Pages : 4
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Author: Harold Abelson
Publisher: Addison-Wesley Professional
ISBN: 0137135599
Category : Computers
Languages : en
Pages : 389
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Book Description
'Blown to Bits' is about how the digital explosion is changing everything. The text explains the technology, why it creates so many surprises and why things often don't work the way we expect them to. It is also about things the information explosion is destroying: old assumptions about who is really in control of our lives.
Author: Richard Pike
Publisher:
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Category : Railroads
Languages : en
Pages : 318
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Category :
Languages : en
Pages : 114
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Author: United States. Congress. House. Committee on Merchant Marine and Fisheries
Publisher:
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Category : Electricians
Languages : en
Pages : 40
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Author: W. Schönfeld
Publisher: Springer Science & Business Media
ISBN: 9783764361860
Category : Medical
Languages : en
Pages : 344
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Book Description
There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery thraea (originally named Streptomyces erythreus). The success of erythromycin, based on its efficacy and tolerability, stimulated researchers throughout the world to undertake intense efforts to understand the biology and chemistry of macrolides and to use this experience to improve the properties of this compound class. The second generation of macrolides, based on chemical modifications of erythromy cin, is currently being in broad use, especially for treatment of respiratory tract infections. We presently foresee the introduction of a new generation of macro lides, i. e. the ketolides, which have the potential to overcome rising resistance problems. This monograph is intended to give the interested reader an overview on "macrolide experience", covering important areas from basic research to clinical use. Starting from a historic overview, the essential basic parameters - efficacy, pharmacokinetics, pharmacodynamics, and pharmacology - are highlighted in order to introduce the reader to the rationale for clinical use of macrolides. The following group of chapters cover the complex chemistry of the macro lactone structures, giving historic background, basic structure-activity relation ships of various derivatization strategies, and perspectives for future discovery of new semisynthetic macrolide antibiotics.
