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Author: Sergej M. Ostojic
Publisher: Academic Press
ISBN: 0323984525
Category : Science
Languages : en
Pages : 714
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Book Description
Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction. - Describes the fundamentals of mitochondria physiology and considers the methods used to evaluate mitochondrial imbalance in clinical practice - Provides broad biochemical and metabolic background on nutritional deficits found in mitochondrial dysfunction - Explores the prevention and treatment of various inherited and acquired disorders associated with mitochondrial dysfunction - Discusses the link between the dosage for each nutrient (nutritional vs. pharmacological) and the clinical effect - Features a dedicated section on whole-diet interventions and mitochondrial function
Author: Sergej M. Ostojic
Publisher: Academic Press
ISBN: 0323984525
Category : Science
Languages : en
Pages : 714
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Book Description
Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction. - Describes the fundamentals of mitochondria physiology and considers the methods used to evaluate mitochondrial imbalance in clinical practice - Provides broad biochemical and metabolic background on nutritional deficits found in mitochondrial dysfunction - Explores the prevention and treatment of various inherited and acquired disorders associated with mitochondrial dysfunction - Discusses the link between the dosage for each nutrient (nutritional vs. pharmacological) and the clinical effect - Features a dedicated section on whole-diet interventions and mitochondrial function
Author: Manlio Vinciguerra
Publisher: Academic Press
ISBN: 0128138637
Category : Technology & Engineering
Languages : en
Pages : 452
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Book Description
Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcriptomics and micro RNA. This book will be a welcomed reference for research scientists and practitioners, including nutritionists and dieticians. - Addresses mother and infant nutrition and its critical impact on the well-being of humankind - Contains coverage from pre-conception to young offspring - Includes pedagogical features (e.g. a list of key facts, mini-dictionaries of terms and definitions, and summary points) to assist in its use as a reference - Contains coverage of emerging fields of molecular biology and important discoveries related to diet and nutritional health
Author: Vinood B. Patel
Publisher: Academic Press
ISBN: 0128119365
Category : Technology & Engineering
Languages : en
Pages : 793
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Book Description
Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book. - Summarizes molecular nutrition in health as related to vitamins - Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis - Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms - Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health - Covers Vitamins A, B, C, D, E, and K - Discusses their impact on health relating to cancer, diabetes, arthritis, and aging - Includes key facts, a mini dictionary of terms, and summary points
Author: Janos Zempleni
Publisher: CABI
ISBN: 0851996795
Category : Medical
Languages : en
Pages : 423
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Book Description
Molecular nutrition (the study of interactions between nutrients and various intracellular and extracellular molecules) is one of the most rapidly developing fields in nutritional science. Ultimately, molecular nutrition research will reveal how nutrients may affect fundamental processes such as DNA repair, cell proliferation, and apoptosis. This book is the only single complete volume available reviewing the field of molecular nutrition. It contains contributions from leading international experts, and reviews the most important and latest research from various areas of molecular nutrition.
Author: Didac Mauricio
Publisher: Academic Press
ISBN: 0128017619
Category : Medical
Languages : en
Pages : 400
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Book Description
Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. - Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus - Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications - Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition
Author: Clara Y. Lim-Sylianco
Publisher:
ISBN:
Category : Molecular biology
Languages : en
Pages : 592
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Book Description
Author: Dominique Dardevet
Publisher: Academic Press
ISBN: 0128023759
Category : Technology & Engineering
Languages : en
Pages : 369
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Book Description
The Molecular Nutrition of Amino Acids and Proteins provides an in-depth look at the involvement and role of amino acids and proteins in molecular nutrition. Editor Dominique Dardevet has assembled a collection of chapters written by leading researchers and top professors that provide the reader with a comprehensive understanding of amino acids and proteins. The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function. The Molecular Nutrition of Amino Acids and Proteins also features reference guides for terms and bullet-point summaries, making it readily accessible to novices while still providing the most up-to-date and detailed information that experienced researchers need. Provides a gentle introduction to the subject by first addressing nutritional information and then building in molecular aspects, clearly establishing fundamental information for the reader Facilitates reader comprehension by including succinct summary points in each chapter Contains a glossary of definitions that allows readers to easily reference terms Provides both a deep and broad understanding of the subject by containing overviews as well as detail-focused chapters
Author: Mark Lucock
Publisher: John Wiley & Sons
ISBN: 0470129379
Category : Medical
Languages : en
Pages : 154
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Book Description
This fascinating book draws it subject matter from a range of relevant disciplines that extend from molecular nutrition, nutritional sciences, and nutrition dietetics through to genetics, genomics, and anthropology. It presents a vital portrait of the absolutely fundamental role that nutrition has played and continues to play in shaping who and what human beings are, as well as where they evolved from, and where they may be heading as a species. Molecular Nutrition: Nutrition and the Evolution of Humankind: Blends coverage of the molecular mechanisms that underpin nutrient-gene interactions with evolutionary theory Takes a molecular biological approach to problem solving, and moves nutrition away from its dietetic and anthropological origins to the front lines of genomic research Covers key concepts in molecular biology; the –omics revolution and bioinformatics; recent human evolution; molecular mechanisms of gene-nutrient interactions; the importance of nutrients and genomics in disease; the evolution of micronutrient metabolism, protein structure, and human disease; nutrients and the human lifecycle; contemporary dietary patterns; leading-edge laboratory tools in nutrigenomics and human evolutionary studies Written by an internationally recognised expert in the field, Molecular Nutrition: Nutrition and the Evolution of Humankind is an invaluable text and reference book for a wide range of teachers, students, and researchers.
Author: Peter F. Surai
Publisher: BRILL
ISBN: 9086869440
Category : Technology & Engineering
Languages : en
Pages : 556
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Book Description
For the last 30 years, polyphenols were in the centre of research work worldwide. Silymarin, an extract from a medicinal plant Silybum marianum, also known as milk thistle, has a special place in this group, having been used in human medicine for the management of liver diseases since ancient times. Accumulating scientific evidence indicates that silymarin is characterised by a wide range of protective pharmacological activities and this topic has received tremendous attention in recent years. However, until now there has been no single monograph addressing major questions related to silymarin chemistry, biochemistry and practical applications. The goal of this book is to provide up to date information about silymarin chemistry, biochemistry and molecular mechanisms of protective actions of this phytochemical with a special emphasis to its vitagene- and transcription factor-modulating properties. Silymarin applications in human diseases, including hepatoprotection, neuroprotection, anti-diabetic, anti-arthritis and other protective activities are reviewed. Immunomodulating, anti-inflammatory, anti-toxic protective activities of silymarin are characterised in detail. Practical applications of silymarin in poultry and animal industry with a special emphasis on its protective roles in gut health maintenance are also presented. This book will be of practical importance to medical and pharmaceutical scientists, including medical doctors, pharmacists, consultants, etc. as well as to poultry/animal scientists, poultry producers, nutritionists and vets, as well as to students of medical, biological and agricultural backgrounds. It can also be of interest for researchers in areas related to physiology, biochemistry, nutrition and veterinary medicine.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
