Molecular Mechanisms of Lymphocyte-mediated Cytotoxicity

Molecular Mechanisms of Lymphocyte-mediated Cytotoxicity PDF Author: Chau-Ching Liu
Publisher:
ISBN:
Category :
Languages : en
Pages : 163

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Book Description

Molecular Mechanisms of Lymphocyte-mediated Cytotoxicity

Molecular Mechanisms of Lymphocyte-mediated Cytotoxicity PDF Author: Chau-Ching Liu
Publisher:
ISBN:
Category :
Languages : en
Pages : 163

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Book Description


Mechanisms of Cell-Mediated Cytotoxicity II

Mechanisms of Cell-Mediated Cytotoxicity II PDF Author: Pierre Henkart
Publisher: Springer Science & Business Media
ISBN: 1468483269
Category : Medical
Languages : en
Pages : 560

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Book Description
This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, June 10-13, 1984. This workshop was organized by an international committee of immunologists interested in lymphocyte cytotoxic mechanisms (G. Berke, W.R. Clark, P. Golstein, M. Hanna, P. Henkart, R. Herberman, H.R. MacDonald, E. Martz, and C. Nathan), who strove to invite participants who have made major contributions to this field. The Workshop was a follow-up to the highly successful 1981 Workshop, whose proceedings Workshop were published by Plenum as Mechanisms in Cell-Mediated Cytotoxicity, edited by W.R. Clark and P. Golstein. That volume has been much appreciated by researchers and students since it contains accounts of most of the current approaches to understanding cytotoxic lymphocyte mechanisms all in one volume. The present book may be viewed as a follow-up to the first one, and in our opinion fairly summarizes the varying current viewpoints on lymphocyte cytotoxic mechanism. It should be noted that the discussions have been transcribed directly by us, and the participants have not had an opportunity to edit their remarks. We have tried to maintain some of the style of the actual discussion in these transcripts. In some cases technical problems prevented usable transcriptions from being made, and hence not all of the actual discussion at the workshop is reproduced here.

Mechanisms of Cell-Mediated Cytotoxicity

Mechanisms of Cell-Mediated Cytotoxicity PDF Author: William R. Clark
Publisher: Springer Science & Business Media
ISBN: 1468489593
Category : Medical
Languages : en
Pages : 577

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Book Description
The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.

Mechanisms of lymphocyte mediated cytotoxicity in health and disease

Mechanisms of lymphocyte mediated cytotoxicity in health and disease PDF Author: Cosima T. Baldari
Publisher: Frontiers Media SA
ISBN: 2832527019
Category : Medical
Languages : en
Pages : 224

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Book Description


Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases

Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases PDF Author: Konrad Krzewski
Publisher: Frontiers Media SA
ISBN: 2889192792
Category : Cell-mediated cytotoxicity
Languages : en
Pages : 164

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Nothing provided

An Investigation of the Molecular Mechanisms of Lymphocyte Cytotoxicity

An Investigation of the Molecular Mechanisms of Lymphocyte Cytotoxicity PDF Author: R. H. R. Ward
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods

Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods PDF Author: SITKOVSKY
Publisher: Springer Science & Business Media
ISBN: 1468468146
Category : Medical
Languages : en
Pages : 528

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Book Description
Our motivation for putting together this book was the need for a single source reference that could be used as an introduction to cell-mediated cytotoxicity for newcomers to this field, such as students and fellows beginning work in our laboratories. At present no such book is available, and we felt that it would be useful as a teaching tool and as a way of conveying our enthusiasm about recent progress in the cytotoxicity field to our colleagues in allied areas. It was with some hesitation that we approached our colleagues with the proposal for this book, and we were pleased to find them very supportive of the idea and willing to participate. We thought it important to broaden the scope of the book to include historical, molecular, cell biological, and clinical aspects of cell-mediated cytotoxicity. To our knowledge this is the first book on cell-mediated cytotoxicity with such a broad scope. Historically, studies on cellular cytotoxicity were part of cellular immunology from its origin. One development of tremendous import was the advent of the 51 Cr assay, which allowed this arm of the immune response to be measured easily and quantitatively. Thus, a readout of this effector pathway is available within a few hours; other immune effector functions can take days or even longer to assay, and the assays are often less quantitative.

Mechanisms of Cell-Mediated Cytotoxicity II

Mechanisms of Cell-Mediated Cytotoxicity II PDF Author: Pierre Henkart
Publisher: Springer
ISBN: 9781468483277
Category : Medical
Languages : en
Pages : 568

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Book Description
This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, June 10-13, 1984. This workshop was organized by an international committee of immunologists interested in lymphocyte cytotoxic mechanisms (G. Berke, W.R. Clark, P. Golstein, M. Hanna, P. Henkart, R. Herberman, H.R. MacDonald, E. Martz, and C. Nathan), who strove to invite participants who have made major contributions to this field. The Workshop was a follow-up to the highly successful 1981 Workshop, whose proceedings Workshop were published by Plenum as Mechanisms in Cell-Mediated Cytotoxicity, edited by W.R. Clark and P. Golstein. That volume has been much appreciated by researchers and students since it contains accounts of most of the current approaches to understanding cytotoxic lymphocyte mechanisms all in one volume. The present book may be viewed as a follow-up to the first one, and in our opinion fairly summarizes the varying current viewpoints on lymphocyte cytotoxic mechanism. It should be noted that the discussions have been transcribed directly by us, and the participants have not had an opportunity to edit their remarks. We have tried to maintain some of the style of the actual discussion in these transcripts. In some cases technical problems prevented usable transcriptions from being made, and hence not all of the actual discussion at the workshop is reproduced here.

Cytotoxic Cells

Cytotoxic Cells PDF Author: M. V. Sitkovskii
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 508

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Book Description
This volume synthesizes recent groundbreaking advances in our knowledge of the molecular mechanisms, biological roles, and medical applications of cytotoxic lymphocytes. Leading investigators examine current concepts on the recognition of antigen by T-cell receptors; the molecules mediating target recognition by natural killer cells; the intracellular signalling cascades triggered by these molecules; and the effector molecules that damage target cells. The contributors present new insights into the roles of cytotoxic lymphocytes in vivo in immune regulation, autoimmunity, antiviral resistance, and tumor surveillance. Several chapters explore potential medical applications of cytotoxic lymphocytes, including vaccines, tumor therapy, and treatment of HIV infection.