Molecular Imaging Through Magnetic Resonance for Clinical Oncology PDF Download
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Author: Karen Belkic
Publisher: Cambridge Int Science Publishing
ISBN: 1904602290
Category : Diagnostic imaging
Languages : en
Pages : 349
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Book Description
Author: Karen Belkic
Publisher: Cambridge Int Science Publishing
ISBN: 1904602290
Category : Diagnostic imaging
Languages : en
Pages : 349
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Book Description
Author: Elke Hattingen
Publisher: Springer
ISBN: 3642450407
Category : Medical
Languages : en
Pages : 166
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Book Description
This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.
Author: Nicole Seiberlich
Publisher: Academic Press
ISBN: 0128170581
Category : Computers
Languages : en
Pages : 1094
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Book Description
Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author: E. Edmund Kim
Publisher: Springer Science & Business Media
ISBN: 9780387950280
Category : Medical
Languages : en
Pages : 322
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Book Description
Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.
Author: Ralph Weissleder
Publisher: PMPH-USA
ISBN: 9781607950059
Category : Medical
Languages : en
Pages : 1384
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Book Description
The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.
Author: Shankar Vallabhajosula
Publisher: Springer Science & Business Media
ISBN: 3540767355
Category : Medical
Languages : en
Pages : 379
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Book Description
Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Author: Jie Tian
Publisher: Springer Science & Business Media
ISBN: 3642343031
Category : Science
Languages : en
Pages : 707
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Book Description
"Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.
Author: Christopher E. Comstock
Publisher: Thieme
ISBN: 162623194X
Category : Medical
Languages : en
Pages : 255
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Book Description
Although mammography is the primary method used for breast cancer screening, screening mammography is limited especially in women with dense breasts, which includes nearly 50% of all women in the United States. Despite improvements such as digital mammography, computed aided detection, and digital breast tomosynthesis, breast cancer continues to be a leading cause of cancer-related death in women. The recent proliferation of screening breast ultrasound has led to increased health care costs and false positives, with only a slight improvement in breast cancer detection. It is time for a better test. This is the first textbook dedicated to the subject of abbreviated breast MRI (AB-MR). The editors are principal investigators in the first multicenter trial evaluating AB-MR. Each chapter is authored by a leading expert in the field of breast MRI. AB-MR only takes 10 minutes or less to perform, has a comparable cost to screening breast ultrasound, and detects twice as many cancers compared to combined screening with mammography and ultrasound. The improved performance of AB-MR is irrespective of breast density, family history, overall breast cancer risk, and cancer characteristics (e.g. type, staging, invasive or intraductal, primary or recurrent). As such, it will likely become a routine screening tool in women with dense breasts. Key Features A background on breast MR imaging including a review of current research data Fundamental guidelines for implementing, performing, and interpreting AB-MR Technical approaches with proven efficacy, including biopsy methods Accurate interpretation presented in an easy-to-read flow chart format More than 250 high quality color illustrations AB-MR has the potential to help radiologists overcome breast cancer screening limitations and change current standards of practice. This book provides radiologists with the necessary tools to quickly incorporate AB-MR into clinical practice, with an ultimate goal of improved breast cancer detection rates and patient outcomes.
Author: Michel M.J. Modo
Publisher: CRC Press
ISBN: 1420004093
Category : Medical
Languages : en
Pages : 456
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Book Description
The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gene expression in living subjects is rapidly moving from the research laboratory into daily clinical settings. The interdisciplinary nature of the field mandates a constant dialogue among molecular and
Author: Habib Zaidi
Publisher: Saunders
ISBN: 9781416049883
Category : Medical
Languages : en
Pages : 240
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Book Description
Currently there is no shortage of challenges and opportunities for PET instrumentation and quantitative imaging techniques. Molecular imaging technologies are leading to a revolutionary paradigm shift in health care and clinical practice. This issue reviews recent advances in PET instrumentation as well as volume correction strategies and strategies for motion tracking and correction, scatter compensation techniques, and attenuation correction techniques.
