Cell & Molecular Biology of Prostate Cancer PDF Download
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Author: Heide Schatten
Publisher: Springer
ISBN: 3319956930
Category : Science
Languages : en
Pages : 135
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Book Description
This volume covers classic and modern cell and molecular biology of prostate cancer, as well as novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation and genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis and progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Cell & Molecular Biology of Prostate Cancer is one of two companion books comprehensively addressing the biology and clinical aspects of prostate cancer. Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, the companion volume, discusses both classic and the most recent imaging approaches including analysis of needle biopsies, applications of nanoparticle probes and peptide-based radiopharmaceuticals for detection, early diagnosis and treatment of prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.
Author: Heide Schatten
Publisher: Springer
ISBN: 3319956930
Category : Science
Languages : en
Pages : 135
Get Book Here
Book Description
This volume covers classic and modern cell and molecular biology of prostate cancer, as well as novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation and genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis and progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Cell & Molecular Biology of Prostate Cancer is one of two companion books comprehensively addressing the biology and clinical aspects of prostate cancer. Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, the companion volume, discusses both classic and the most recent imaging approaches including analysis of needle biopsies, applications of nanoparticle probes and peptide-based radiopharmaceuticals for detection, early diagnosis and treatment of prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.
Author: Gary Cook
Publisher: Springer
ISBN: 3319576240
Category : Medical
Languages : en
Pages : 73
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Book Description
This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, which presents contributions from professionals worldwide who share a common purpose in promoting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
Author: Brian D. Robinson
Publisher: Springer
ISBN: 3319640968
Category : Medical
Languages : en
Pages : 564
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Book Description
This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) and Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.
Author: Temel Tirkes
Publisher: Springer Nature
ISBN: 3030459357
Category : Medical
Languages : en
Pages : 234
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Book Description
This book is a basic, practical guide to performing and interpreting state-of-the-art prostate MRI, utilizing the latest guidelines in the field. Prostate MRI has become one of the fastest growing examinations in the radiology practice, and this demand has continuously increased within the past decade. Since it is relatively new, MRI of the prostate is predominantly being performed at academic institutions, however there is a growing demand within the lower-tier health care institutions to offer this examination to their patients. This is an ideal guide for radiologists who want to enhance or initiate prostate MRI service for their referring clinicians and as a manual for technologists and those who are in training. Prostate cancer is the second leading cause of cancer death in men, exceeded only by lung cancer. The best predictor of disease outcome lies with correct diagnosis, which requires precise imaging and diagnostic procedures aided by prostate MRI. Urologists, medical oncologists and radiation oncologists all agree that multi-parametric prostate MRI is essential for evaluation of prostate cancer. However, the technical aspects of prostate MR imaging are not as straightforward as for the other imaging modalities and constantly evolving. Its small size presents a real challenge to the radiologist, who needs to do the T2 and diffusion weighted images and perform a dynamic contrast enhanced sequence correctly. These images may also need to be analyzed on an independent workstation. Due to the absence of a current reference manual, when a radiologist wants to establish a prostate imaging service, he/she needs to attend dedicated prostate MR workshops or dive into the literature search alone, only to get more confused about what to do and how to do it. With this book, expert authors were asked to give clear guidance to those who want to enhance or initiate their prostate imaging service. With this much-needed, concise, practical guidance, radiologists can perform and interpret multi-parametric prostate MRI in a standardized fashion, in concordance with PI-RADS v2.1 that can be applicable to all available hardware platforms (GE, Philips, Siemens, Toshiba). Additionally, they can perform post-processing for possible targeted biopsy and interpret post-therapy and PET studies. The book discusses imaging protocols (planning and prescription) and sequence parameters with representative images for each MRI sequence. This handbook-style practical manual can be used in the radiology reading room by those interpreting the MR exam as a reference as well as at the MRI scanner by the technologists as a guide. Coverage of basic prostate anatomy, pathology, Urologists’ point of view, MRI guided radiation treatment planning and molecular imaging is also included. Throughout the book, authors will discuss basics, pitfalls, and provide tips in image acquisition and interpretation, alongside several case examples.
Author: Kamla Kant Shukla
Publisher: Springer
ISBN: 981135877X
Category : Medical
Languages : en
Pages : 339
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Book Description
This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.
Author: Andreas Maier
Publisher: Springer
ISBN: 3319965204
Category : Computers
Languages : en
Pages : 263
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Book Description
This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.
Author: Jason S. Lewis
Publisher: Springer
ISBN: 3319989472
Category : Medical
Languages : en
Pages : 648
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Book Description
This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.
Author: Habib Zaidi
Publisher: Saunders
ISBN: 9781416049883
Category : Medical
Languages : en
Pages : 240
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Book Description
Currently there is no shortage of challenges and opportunities for PET instrumentation and quantitative imaging techniques. Molecular imaging technologies are leading to a revolutionary paradigm shift in health care and clinical practice. This issue reviews recent advances in PET instrumentation as well as volume correction strategies and strategies for motion tracking and correction, scatter compensation techniques, and attenuation correction techniques.
Author: Manfred Wirth
Publisher: Walter de Gruyter
ISBN: 3110807270
Category : Medical
Languages : en
Pages : 220
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Book Description
Author: Duccio Volterrani
Publisher: Springer
ISBN: 3319955640
Category : Medical
Languages : en
Pages : 1331
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Book Description
Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or surgical procedures. Accordingly, today’s nuclear medicine specialists are actually specialists in multimodality imaging (in addition to their expertise in the diagnostic and therapeutic uses of radionuclides). This new role requires a new core curriculum for training nuclear medicine specialists. This textbook is designed to meet these new educational needs, and to prepare nuclear physicians and technologists for careers in this exciting specialty.
