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Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470090820
Category : Science
Languages : en
Pages : 306
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Book Description
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, which requires the existence of photopigments sensitive to light. The exact identity of the molecules involved in circadian photoreception has remained elusive. The classical view of the circadian system is of diverse physiological rhythms regulated by a centralized clock structure. This book presents evidence that challenges this view. Experiments in both vertebrate and invertebrate systems demonstrate that the circadian timing system is dispersed throughout the animal and suggest that possibly every cell contains an autonomous clock mechanism. A variety of tissues and cells contain have been shown to maintain an oscillation when placed in vitro and removed from any external cues or signals that originate from the classical clock structures and/or the environment. This book draws together contributions from an international and interdisciplinary group of experts whose work is focused on all aspects of the topic. Coverage includes the mechanisms of light signalling to the vertebrate clock, the connections between central and peripheral clocks, circadian gene expression patterns and output pathways of clock mechanisms.
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470090820
Category : Science
Languages : en
Pages : 306
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Book Description
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, which requires the existence of photopigments sensitive to light. The exact identity of the molecules involved in circadian photoreception has remained elusive. The classical view of the circadian system is of diverse physiological rhythms regulated by a centralized clock structure. This book presents evidence that challenges this view. Experiments in both vertebrate and invertebrate systems demonstrate that the circadian timing system is dispersed throughout the animal and suggest that possibly every cell contains an autonomous clock mechanism. A variety of tissues and cells contain have been shown to maintain an oscillation when placed in vitro and removed from any external cues or signals that originate from the classical clock structures and/or the environment. This book draws together contributions from an international and interdisciplinary group of experts whose work is focused on all aspects of the topic. Coverage includes the mechanisms of light signalling to the vertebrate clock, the connections between central and peripheral clocks, circadian gene expression patterns and output pathways of clock mechanisms.
Author:
Publisher: Academic Press
ISBN: 0123876982
Category : Science
Languages : en
Pages : 269
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Book Description
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
Author: Urs Albrecht
Publisher: Springer Science & Business Media
ISBN: 1441912622
Category : Science
Languages : en
Pages : 306
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Book Description
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author: Pavol Svorc
Publisher: BoD – Books on Demand
ISBN: 1789849004
Category : Medical
Languages : en
Pages : 109
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Book Description
The regular alternation of light and dark affects not only human biological systems, but also the social organization of behavior. The effect of such light modes is manifested in periodic changes in physiological functions and biological rhythms exhibited at every level of life. The book discusses some of the specificities of the circadian rhythms in living organisms and mentions aspects of the control of circadian rhythms as well as experimental and clinical cases that are closely related to circadian disruption. This book can evoke interest in many researchers who want to use this information for the advancement of their research towards a better understanding of the biological time structure.
Author:
Publisher: Elsevier
ISBN: 0128114320
Category : Medical
Languages : en
Pages : 3421
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Book Description
Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases
Author: Eberhard Schäfer
Publisher: Springer Science & Business Media
ISBN: 9781402038105
Category : Nature
Languages : en
Pages : 724
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Book Description
Plants as sessile organisms have evolved fascinating capacities to adapt to changes in their natural environment. Arguably, light is by far the most important and variable environmental factor. The quality, quantity, direction and duration of light is monitored by a series of photoreceptors covering spectral information from UVB to near infrared. The response of the plants to light is called photomorphogenesis and it is regulated by the concerted action of photoreceptors. The combined techniques of action spectroscopy and biochemistry allowed one of the important photoreceptors – phytochrome – to be identified in the middle of the last century. An enormous number of physiological studies published in the last century describe the properties of phytochrome and its function and also the physiology of blue and UV-B photoreceptors, unidentified at the time. This knowledge was summarized in the advanced textbook “Photomorphogenesis in Plants” (Kendrick and Kronenberg, eds., 1986, 1994). With the advent of molecular biology, genetics and new molecular, cellular techniques, our knowledge in the field of photomorphogenesis has dramatically increased over the last 15 years.
Author: Angelos Tsipis
Publisher: BoD – Books on Demand
ISBN: 1789855551
Category : Medical
Languages : en
Pages : 132
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Book Description
In the field of cardiology, some of the most dramatic advances in recent years have come from understanding the molecular and cellular basis of cardiovascular disease. Knowledge of the pathological basis of disease in some cases allows the development of new strategies for prevention and treatment. This book was planned not only to convey new facts on cardiovascular diseases, but also to boost the excitement and challenges of research in the dynamic area of modern molecular and cellular biology of cardiology. The integration of multilevel biological data and the connection with clinical practice reveal the potential of personalized medicine, with future implications for prognosis, diagnosis, and management of cardiovascular diseases.
Author: Fabian-Xosé Fernandez
Publisher: Frontiers Media SA
ISBN: 2889714977
Category : Medical
Languages : en
Pages : 203
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Book Description
Author: Joseph Besharse
Publisher: Academic Press
ISBN: 012374203X
Category : Science
Languages : en
Pages : 2352
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Book Description
As the first comprehensive reference for the eye, its support structures, diseases, and treatments, Encyclopedia of the Eye is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues. This Encyclopedia is invaluable for graduate students and postdoctoral fellows who are seeking an introduction to an area of eye research. Each chapter explains the basic concepts and provides references to relevant chapters within the Encyclopedia and more detailed articles across the wider research literature. The Encyclopedia is also particularly useful for visual scientists and practitioners who are researching a new area, seeking deeper understanding of important research articles in fields adjacent to their own, or reviewing a grant outside their immediate area of expertise. Written by experts at a level that permits students to grasp key elements of a specific subject Provides an entryway into the major features of current eye research No other source puts this much information, so well-indexed and with so many helpful full color figures and graphics, in the hands of the ophthalmic scientist
Author: José A. Munoz-Cueto
Publisher: CRC Press
ISBN: 1498727840
Category : Nature
Languages : en
Pages : 405
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Book Description
This book reviews up-to-date knowledge on the biology of sole (Solea senegalensis and S. solea). These flatfish species are increasingly important in Europe both from the ecological and production point of view. This book is divided into two sections: A. general fisheries, aquaculture and engineering overviews; B. physiological, developmental, rhythmic, welfare and genetic aspects which will be of immense interest for the aquaculture industry. Experts, from both academia and research institutes, provide their expertise on sole biology.
